Canonical NOTCH signaling controls the early progenitor state and emergence of the medullary epithelial lineage in fetal thymus development

Autor: Freddy Radtke, Popis M, Kousa Ai, Farley Am, O’Neill Ke, Liu D, Guillemot F, Tomlinson, Ute Koch, Svetlana Ulyanchenko, Philip A. Seymour, C. Clare Blackburn, Palle Serup

Thymus function depends on the epithelial compartment of the thymic stroma. Cortical thymic epithelial cells (cTECs) regulate T cell lineage commitment and positive selection, while medullary (m) TECs impose central tolerance on the T cell repertoire

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Classification of Human Ovarian Follicle Morphology: Recommendations of the NICHD-Sponsored Ovarian Nomenclature Workshop.

Autor: Yano Maher JC; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD,. Electronic address: maherjy@nih.gov., Zelinski MB; Oregon National Primate Research Center, Beaverton, OR, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR., Oktay KH; Laboratory of Molecular Reproduction and Fertility Preservation, Yale School of Medicine, New Haven, CT., Duncan FE; Department of Obstetrics & Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL., Segars JH; Division of Reproductive Science and Women's Health Research, Johns Hopkins University, Baltimore, MD., Lujan ME; Division of Nutritional Sciences, College of Human Ecology, Cornell University, Ithaca, NY., Lou H; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., Yun B; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., Hanfling SN; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., Schwartz LE; University of Pennsylvania, Division of Pathology and Laboratory Medicine., Laronda MM; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago,; Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL,; Department of Obstetrics & Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL., Halvorson LM; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., O'Neill KE; University of Pennsylvania, Division of Reproductive Endocrinology and Infertility., Gomez-Lobo V; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.

Publikováno v: Fertility and sterility [Fertil Steril] 2024 Nov 14. Date of Electronic Publication: 2024 Nov 14.

Open-source graphical user interface for the creation of synthetic skeletons for medical image analysis.

Autor: Herz C; Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, Philadelphia, Pennsylvania, United States., Vergnet N; University of Pennsylvania, Penn Image Computing and Science Laboratory, Department of Radiology, Philadelphia, Pennsylvania, United States., Tian S; University of Pennsylvania, Penn Image Computing and Science Laboratory, Department of Radiology, Philadelphia, Pennsylvania, United States., Aly AH; University of Pennsylvania, Penn Image Computing and Science Laboratory, Department of Radiology, Philadelphia, Pennsylvania, United States., Jolley MA; Children's Hospital of Philadelphia, Department of Anesthesiology and Critical Care Medicine, Philadelphia, Pennsylvania, United States.; Children's Hospital of Philadelphia, Division of Cardiology, Philadelphia, Pennsylvania, United States., Tran N; Jefferson Einstein Hospital, Division of Cardiovascular Diseases, Philadelphia, Pennsylvania, United States., Arenas G; University of Pennsylvania, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Philadelphia, Pennsylvania, United States., Lasso A; Queen's University, School of Computing, Laboratory for Percutaneous Surgery, Kingston, Ontario, Canada., Schwartz N; University of Pennsylvania, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Philadelphia, Pennsylvania, United States., O'Neill KE; University of Pennsylvania, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Philadelphia, Pennsylvania, United States., Yushkevich PA; University of Pennsylvania, Penn Image Computing and Science Laboratory, Department of Radiology, Philadelphia, Pennsylvania, United States., Pouch AM; University of Pennsylvania, Penn Image Computing and Science Laboratory, Department of Radiology, Philadelphia, Pennsylvania, United States.; University of Pennsylvania, Department of Bioengineering, Philadelphia, Pennsylvania, United States.

Publikováno v: Journal of medical imaging (Bellingham, Wash.) [J Med Imaging (Bellingham)] 2024 May; Vol. 11 (3), pp. 036001. Date of Electronic Publication: 2024 May 14.