Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.

Autor: Sharp, Fiona A., Ruane, Darren, Claass, Benjamin, Creagh, Emma, Harris, James, Malyala, Padma, Singh, Manomohan, O'Hagan, Derek T., Pétrilli, Virginie, Tschopp, Jurg, O'NeiII, Luke A. J., LaveII, Ed C.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 1/20/2009, Vol. 106 Issue 3, p870-875, 6p, 1 Color Photograph, 5 Graphs

TILRR, a Novel IL-1RI Co-receptor, Potentiates MyD88 Recruitment to Control Ras-dependent Amplification of NF-κB.

Autor: Xiao Zhang¹, Shephard, Freya¹, Kim, Hong B.¹, Palmer, Ian R.¹, McHarg, Selina¹, Fowler, Gregory J. S.¹, O'NeiII, Luke A. J.², Kiss-Toth, Endre³, Qwarnstrom, Eva E.^1,4 e.qwarnstrom@sheffield.ac.uk

Publikováno v: Journal of Biological Chemistry. 3/5/2010, Vol. 285 Issue 10, p7222-7232. 11p.