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A genome-wide association study to identify genetic markers associated with endometrial cancer grade
Autor:
O’Mara T, Duffy D, Thompson DJ, Ahmed S, Ferguson K, Healey CS, Montgomery G, Shah M, Morrison J, Pharoah PP, Dunning AM, Webb PM, Easton DF, Spurdle AB
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 10, Iss Suppl 2, p A47 (2012)
Externí odkaz:
https://doaj.org/article/a403fdcd90b94c30a32501d64a0d00aa
Autor:
Zhang, H. (Haoyu), Ahearn, T. U. (Thomas U.), Lecarpentier, J. (Julie), Barnes, D. (Daniel), Beesley, J. (Jonathan), Qi, G. (Guanghao), Hang, X. (Xia), O'Mara, T. A. (Tracy A.), Zhao, N. (Ni), Bolla, M. K. (Manjeet K.), Dunning, A. M. (Alison M.), Dennis, J. (Joe), Wang, Q. (Qin), Abu Ful, Z. (Zumuruda), Aittomaki, K. (Kristiina), Andrulis, I. L. (Irene L.), Anton-Culver, H. (Hoda), Arndt, V. (Volker), Aronson, K. J. (Kristan J.), Arun, B. K. (Banu K.), Auer, P. L. (Paul L.), Azzollini, J. (Jacopo), Barrowdale, D. (Daniel), Becher, H. (Heiko), Beckmann, M. W. (Matthias W.), Behrens, S. (Sabine), Benitez, J. (Javier), Bermisheva, M. (Marina), Bialkowska, K. (Katarzyna), Blanco, A. (Ana), Blomqvist, C. (Carl), Bogdanova, N. V. (Natalia, V), Bojesen, S. E. (Stig E.), Bonanni, B. (Bernardo), Bondavalli, D. (Davide), Borg, A. (Ake), Brauch, H. (Hiltrud), Brenner, H. (Hermann), Briceno, I. (Ignacio), Broeks, A. (Annegien), Brucker, S. Y. (Sara Y.), Bruening, T. (Thomas), Burwinkel, B. (Barbara), Buys, S. S. (Saundra S.), Byers, H. (Helen), Caldes, T. (Trinidad), Caligo, M. A. (Maria A.), Calvello, M. (Mariarosaria), Campa, D. (Daniele), Castelao, J. E. (Jose E.), Chang-Claude, J. (Jenny), Chanock, S. J. (Stephen J.), Christiaens, M. (Melissa), Christiansen, H. (Hans), Chung, W. K. (Wendy K.), Claes, K. B. (Kathleen B. M.), Clarke, C. L. (Christine L.), Cornelissen, S. (Sten), Couch, F. J. (Fergus J.), Cox, A. (Angela), Cross, S. S. (Simon S.), Czene, K. (Kamila), Daly, M. B. (Mary B.), Devilee, P. (Peter), Diez, O. (Orland), Domchek, S. M. (Susan M.), Doerk, T. (Thilo), Dwek, M. (Miriam), Eccles, D. M. (Diana M.), Ekici, A. B. (Arif B.), Evans, D. G. (D. Gareth), Fasching, P. A. (Peter A.), Figueroa, J. (Jonine), Foretova, L. (Lenka), Fostira, F. (Florentia), Friedman, E. (Eitan), Frost, D. (Debra), Gago-Dominguez, M. (Manuela), Gapstur, S. M. (Susan M.), Garber, J. (Judy), Garcia-Saenz, J. A. (Jose A.), Gaudet, M. M. (Mia M.), Gayther, S. A. (Simon A.), Giles, G. G. (Graham G.), Godwin, A. K. (Andrew K.), Goldberg, M. S. (Mark S.), Goldgar, D. E. (David E.), Gonzalez-Neira, A. (Anna), Greene, M. H. (Mark H.), Gronwald, J. (Jacek), Guenel, P. (Pascal), Haeberle, L. (Lothar), Hahnen, E. (Eric), Haiman, C. A. (Christopher A.), Hake, C. R. (Christopher R.), Hall, P. (Per), Hamann, U. (Ute), Harkness, E. F. (Elaine F.), Heemskerk-Gerritsen, B. A. (Bernadette A. M.), Hillemanns, P. (Peter), Hogervorst, F. B. (Frans B. L.), Holleczek, B. (Bernd), Hollestelle, A. (Antoinette), Hooning, M. J. (Maartje J.), Hoover, R. N. (Robert N.), Hopper, J. L. (John L.), Howell, A. (Anthony), Huebner, H. (Hanna), Hulick, P. J. (Peter J.), Imyanitov, E. N. (Evgeny N.), Isaacs, C. (Claudine), Izatt, L. (Louise), Jager, A. (Agnes), Jakimovska, M. (Milena), Jakubowska, A. (Anna), James, P. (Paul), Janavicius, R. (Ramunas), Janni, W. (Wolfgang), John, E. M. (Esther M.), Jones, M. E. (Michael E.), Jung, A. (Audrey), Kaaks, R. (Rudolf), Kapoor, P. M. (Pooja Middha), Karlan, B. Y. (Beth Y.), Keeman, R. (Renske), Khan, S. (Sofia), Khusnutdinova, E. (Elza), Kitahara, C. M. (Cari M.), Ko, Y.-D. (Yon-Dschun), Konstantopoulou, I. (Irene), Koppert, L. B. (Linetta B.), Koutros, S. (Stella), Kristensen, V. N. (Vessela N.), Laenkholm, A.-V. (Anne-Vibeke), Lambrechts, D. (Diether), Larsson, S. C. (Susanna C.), Laurent-Puig, P. (Pierre), Lazaro, C. (Conxi), Lazarova, E. (Emilija), Lejbkowicz, F. (Flavio), Leslie, G. (Goska), Lesueur, F. (Fabienne), Lindblom, A. (Annika), Lissowska, J. (Jolanta), Lo, W.-Y. (Wing-Yee), Loud, J. T. (Jennifer T.), Lubinski, J. (Jan), Lukomska, A. (Alicja), Maclnnis, R. J. (Robert J.), Mannermaa, A. (Arto), Manoochehri, M. (Mehdi), Manoukian, S. (Siranoush), Margolin, S. (Sara), Martinez, M. E. (Maria Elena), Matricardi, L. (Laura), McGuffog, L. (Lesley), McLean, C. (Catriona), Mebirouk, N. (Noura), Meindl, A. (Alfons), Menon, U. (Usha), Miller, A. (Austin), Mingazheva, E. (Elvira), Montagna, M. (Marco), Mulligan, A. M. (Anna Marie), Mulot, C. (Claire), Muranen, T. A. (Taru A.), Nathanson, K. L. (Katherine L.), Neuhausen, S. L. (Susan L.), Nevanlinna, H. (Heli), Neven, P. (Patrick), Newman, W. G. (William G.), Nielsens, F. C. (Finn C.), Nikitina-Zake, L. (Liene), Nodora, J. (Jesse), Offit, K. (Kenneth), Olah, E. (Edith), Olopade, O. I. (Olufunmilayo, I), Olsson, H. (Hakan), Orr, N. (Nick), Papi, L. (Laura), Papp, J. (Janos), Park-Simon, T.-W. (Tjoung-Won), Parsons, M. T. (Michael T.), Peissel, B. (Bernard), Peixoto, A. (Ana), Peshkin, B. (Beth), Peterlongo, P. (Paolo), Peto, J. (Julian), Phillips, K.-A. (Kelly-Anne), Piedmonte, M. (Marion), Plaseska-Karanfilska, D. (Dijana), Prajzendanc, K. (Karolina), Prentice, R. (Ross), Prokofyeva, D. (Darya), Rack, B. (Brigitte), Radice, P. (Paolo), Ramus, S. J. (Susan J.), Rantala, J. (Johanna), Rashid, M. U. (Muhammad U.), Rennert, G. (Gad), Rennert, H. S. (Hedy S.), Risch, H. A. (Harvey A.), Romero, A. (Atocha), Rookus, M. A. (Matti A.), Ruebner, M. (Matthias), Ruediger, T. (Thomas), Saloustros, E. (Emmanouil), Sampson, S. (Sarah), Sandler, D. P. (Dale P.), Sawyer, E. J. (Elinor J.), Scheuner, M. T. (Maren T.), Schmutzler, R. K. (Rita K.), Schneeweiss, A. (Andreas), Schoemaker, M. J. (Minouk J.), Schoettker, B. (Ben), Schuermann, P. (Peter), Senter, L. (Leigha), Sharma, P. (Priyanka), Sherman, M. E. (Mark E.), Shu, X.-O. (Xiao-Ou), Singer, C. F. (Christian F.), Smichkoska, S. (Snezhana), Soucy, P. (Penny), Southey, M. C. (Melissa C.), Spinelli, J. J. (John J.), Stone, J. (Jennifer), Stoppa-Lyonnet, D. (Dominique), Swerdlow, A. J. (Anthony J.), Szabo, C. I. (Csilla, I), Tamimi, R. M. (Rulla M.), Tapper, W. J. (William J.), Taylor, J. A. (Jack A.), Teixeira, M. R. (Manuel R.), Terry, M. (MaryBeth), Thomassen, M. (Mads), Thull, D. L. (Darcy L.), Tischkowitz, M. (Marc), Toland, A. E. (Amanda E.), Tollenaar, R. A. (Rob A. E. M.), Tomlinson, I. (Ian), Torres, D. (Diana), Troester, M. A. (Melissa A.), Truong, T. (Therese), Tung, N. (Nadine), Untch, M. (Michael), Vachon, C. M. (Celine M.), van den Ouweland, A. M. (Ans M. W.), van der Kolk, L. E. (Lizet E.), van Veen, E. M. (Elke M.), vanRensburg, E. J. (Elizabeth J.), Vega, A. (Ana), Wappenschmidt, B. (Barbara), Weinberg, C. R. (Clarice R.), Weitzel, J. N. (Jeffrey N.), Wildiers, H. (Hans), Winqvist, R. (Robert), Wolk, A. (Alicja), Yang, X. R. (Xiaohong R.), Yannoukakos, D. (Drakoulis), Zheng, W. (Wei), Zorn, K. K. (Kristin K.), Milne, R. L. (Roger L.), Kraft, P. (Peter), Simard, J. (Jacques), Pharoah, P. D. (Paul D. P.), Michailidou, K. (Kyriaki), Antoniou, A. C. (Antonis C.), Schmidt, M. K. (Marjanka K.), Chenevix-Trench, G. (Georgia), Easton, D. F. (Douglas F.), Chatterjee, N. (Nilanjan), Garcia-Closas, M. (Montserrat)
Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls, plus 18,908 BRCA1 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::82993b9cd994de5513c8fab7aae37821
http://urn.fi/urn:nbn:fi-fe2020070947186
http://urn.fi/urn:nbn:fi-fe2020070947186
Autor:
O'Mara, T, Glubb, D, Amant, F, Annibali, D, Ashton, K, Attia, J, Auer, P, Beckmann, M, Black, A, Humphreys, M, Brauch, H, Brenner, H, Brinton, L, Buchanan, D, Burwinkel, B, Chang-Claude, J, Chanock, S, Chen, C, Chen, M, Cheng, T, Clarke, C, Clendenning, M, Cook, L, Couch, F, Cox, A, Crous-Bou, M, Czene, K, Day, F, Dennis, J, Depreeuw, J, Doherty, JA, Dork, T, Dowdy, S, Dürst, M, Ekici, A, Fasching, P, Fridley, B, Friedenreich, C, Fritschi, L, Fung, J, Garcia-Closas, M, Gaudet, M, Giles, G, Goode, E, Gorman, M, Haiman, C, Hall, P, Hankinson, S, Healey, C, Hein, A, Hillemanns, P, Hodgson, S, Hoivik, E, Holliday, E, Hopper, J, Hunter, D, Jones, A, Krakstad, C, Kristensen, V, Lambrechts, D, Le Marchand, L, Liang, X, Lindblom, A, Lissowska, J, Long, J, Lu, L, Magliocco, A, Martin, L, McEvoy, M, Meindl, A, Michailidou, K, Milne, R, Mints, M, Montgomery, G, Nassir, R, Olsson, H, Orlow, I, Sacerdote, G, Sarto, G, Schumacher, F, Scott, R, Setiawan, VW, Shah, M, Sheng, M, Shu, X-O, Southey, M, Swerdlow, A, Tham, E, Trovik, J, Wolk, A, Xia, L, Xiang, YB, Yang, H, Yu, H, Zheng, W, Pharoah, P, Dunning, A, Kraft, P, De Vivo, I, Tomlinson, I, Easton, D, Spurdle, A, Thompson, D
Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial cancer. Here, we present a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1dfae1a85e0882274be821ef3eaf821d
https://openaccess.sgul.ac.uk/id/eprint/110042/1/s41467-018-05427-7.pdf
https://openaccess.sgul.ac.uk/id/eprint/110042/1/s41467-018-05427-7.pdf
Autor:
Collaboration, Telomeres Mendelian Randomization, Haycock, P, Burgess, S, Nounu, A, Zheng, J, Okoli, G, Bowden, J, Wade, K, Timpson, N, Evans, D, Willeit, P, Aviv, A, Gaunt, T, Hemani, G, Mangino, M, Ellis, H, Kurian, K, Pooley, K, Eeles, R, Lee, J, Fang, S, Chen, W, Law, M, Bowdler, L, Iles, M, Yang, Q, Worrall, B, Markus, H, Hung, R, Amos, C, Spurdle, A, Thompson, D, O'Mara, T, Wolpin, B, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N, Lund, E, Duell, E, Canzian, F, Severi, G, Overvad, K, Gunter, M, Tumino, R, Svenson, U, van Rij, A, Baas, A, Bown, M, Samani, N, van t'Hof, F, Tromp, G, Jones, G, Kuivaniemi, H, Elmore, J, Johansson, M, Mckay, J, Scelo, G, Carreras-Torres, R, Gaborieau, V, Brennan, P, Bracci, P, Neale, R, Olson, S, Gallinger, S, Li, D, Petersen, G, Risch, H, Klein, A, Han, J, Abnet, C, Freedman, N, Taylor, P, Maris, J, Aben, K, Kiemeney, L, Vermeulen, S, Wiencke, J, Walsh, K, Wrensch, M, Rice, T, Turnbull, C, Litchfield, K, Paternoster, L, Standl, M, Abecasis, G, SanGiovanni, J, Li, Y, Mijatovic, V, Sapkota, Y, Low, S, Zondervan, K, Montgomery, G, Nyholt, D, van Heel, D, Hunt, K, Arking, D, Ashar, F, Sotoodehnia, N, Woo, D, Rosand, J, Comeau, M, Brown, W, Silverman, E, Hokanson, J, Cho, M, Hui, J, Ferreira, M, Thompson, P, Morrison, A, Felix, J, Smith, N, Christiano, A, Petukhova, L, Betz, R, Fan, X, Zhang, X, Zhu, C, Langefeld, C, Thompson, S, Wang, F, Lin, X, Schwartz, D, Fingerlin, T, Rotter, J, Cotch, M, Jensen, R, Munz, M, Dommisch, H, Schaefer, A, Han, F, Ollila, H, Hillary, R, Albagha, O, Ralston, S, Zeng, C, Zheng, W, Shu, X, Reis, A, Uebe, S, Hüffmeier, U, Kawamura, Y, Otowa, T, Sasaki, T, Hibberd, M, Davila, S, Xie, G, Siminovitch, K, Bei, J, Zeng, Y, Försti, A, Chen, B, Landi, S, Franke, A, Fischer, A, Ellinghaus, D, Flores, C, Noth, I, Ma, S, Foo, J, Liu, J, Kim, J, Cox, D, Delattre, O, Mirabeau, O, Skibola, C, Tang, C, Garcia-Barcelo, M, Chang, K, Su, W, Chang, Y, Martin, N, Gordon, S, Wade, T, Lee, C, Kubo, M, Cha, P, Nakamura, Y, Levy, D, Kimura, M, Hwang, S, Hunt, S, Spector, T, Soranzo, N, Manichaikul, A, Barr, R, Kahali, B, Speliotes, E, Yerges-Armstrong, L, Cheng, C, Jonas, J, Wong, T, Fogh, I, Lin, K, Powell, J, Rice, K, Relton, C, Martin, R, Davey Smith, G
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Haycock, P C, Burgess, S, Nounu, A, Zheng, J, Okoli, G N, Bowden, J, Wade, K H, Timpson, N J, Evans, D M, Willeit, P, Aviv, A, Gaunt, T R, Hemani, G, Mangino, M, Ellis, H P, Kurian, K M, Pooley, K A, Eeles, R A, Lee, J E, Fang, S, Chen, W V, Law, M H, Bowdler, L M, Iles, M M, Yang, Q, Worrall, B B, Markus, H S, Hung, R J, Amos, C I, Spurdle, A B, Thompson, D J, O'Mara, T A, Wolpin, B, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N C, Lund, E, Duell, E J, Canzian, F, Severi, G, Overvad, K, Gunter, M J, Tumino, R, Brennan, P, Paternoster, L, Soranzo, N, Relton, C L, Martin, R M, Davey Smith, G 2017, ' Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases : A Mendelian Randomization Study ', JAMA Oncology, vol. 3, no. 5, pp. 636-651 . https://doi.org/10.1001/jamaoncol.2016.5945
Dipòsit Digital de la UB
Universidad de Barcelona
Jama Oncology, 3, 636-651
JAMA Oncol. 3, 636-651 (2017)
Jama Oncology, 3, 5, pp. 636-651
Haycock, P C, Burgess, S, Nounu, A, Zheng, J, Okoli, G N, Bowden, J, Wade, K H, Timpson, N J, Evans, D M, Willeit, P, Aviv, A, Gaunt, T R, Hemani, G, Mangino, M, Ellis, H P, Kurian, K M, Pooley, K A, Eeles, R A, Lee, J E, Fang, S, Chen, W V, Law, M H, Bowdler, L M, Iles, M M, Yang, Q, Worrall, B B, Markus, H S, Hung, R J, Amos, C I, Spurdle, A B, Thompson, D J, O'Mara, T A, Wolpin, B M, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N C, Lund, E, Duell, E J, Canzian, F, Severi, G, Overvad, K, Gunter, M J, Tumino, R, Svenson, U, van Rij, A, Baas, A F, Bown, M J, Samani, N J, van t'Hof, F N G & Telomeres Mendelian Randomization Collaboration 2017, ' Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases : A Mendelian Randomization Study ', JAMA Oncology, vol. 3, no. 5, pp. 636-651 . https://doi.org/10.1001/jamaoncol.2016.5945
Haycock, P C, Burgess, S, Nounu, A, Zheng, J, Okoli, G N, Bowden, J, Wade, K H, Timpson, N J, Evans, D M, Willeit, P, Aviv, A, Gaunt, T R, Hemani, G, Mangino, M, Ellis, H P, Kurian, K M, Pooley, K A, Eeles, R A, Lee, J E, Fang, S, Chen, W V, Law, M H, Bowdler, L M, Iles, M M, Yang, Q, Worrall, B B, Markus, H S, Hung, R J, Amos, C I, Spurdle, A B, Thompson, D J, O'Mara, T A, Wolpin, B, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N C, Lund, E, Duell, E J, Canzian, F, Severi, G, Overvad, K, Gunter, M J, Tumino, R, Svenson, U, van Rij, A, Baas, A F, Bown, M J & Albagha, O & Ralston, S H 2017, ' Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases : A Mendelian Randomization Study ', JAMA Oncology, vol. 3, no. 5, pp. 636-651 . https://doi.org/10.1001/jamaoncol.2016.5945
JAMA Oncology, 3(5), 636-651. American Medical Association
instname
Haycock, P C, Burgess, S, Nounu, A, Zheng, J, Okoli, G N, Bowden, J, Wade, K H, Timpson, N J, Evans, D M, Willeit, P, Aviv, A, Gaunt, T R, Hemani, G, Mangino, M, Ellis, H P, Kurian, K M, Pooley, K A, Eeles, R A, Lee, J E, Fang, S, Chen, W V, Law, M H, Bowdler, L M, Iles, M M, Yang, Q, Worrall, B B, Markus, H S, Hung, R J, Amos, C I, Spurdle, A B, Thompson, D J, O'Mara, T A, Wolpin, B, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N C, Lund, E, Duell, E J, Canzian, F, Severi, G, Overvad, K, Gunter, M J, Tumino, R, Brennan, P, Paternoster, L, Soranzo, N, Relton, C L, Martin, R M, Davey Smith, G 2017, ' Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases : A Mendelian Randomization Study ', JAMA Oncology, vol. 3, no. 5, pp. 636-651 . https://doi.org/10.1001/jamaoncol.2016.5945
Dipòsit Digital de la UB
Universidad de Barcelona
Jama Oncology, 3, 636-651
JAMA Oncol. 3, 636-651 (2017)
Jama Oncology, 3, 5, pp. 636-651
Haycock, P C, Burgess, S, Nounu, A, Zheng, J, Okoli, G N, Bowden, J, Wade, K H, Timpson, N J, Evans, D M, Willeit, P, Aviv, A, Gaunt, T R, Hemani, G, Mangino, M, Ellis, H P, Kurian, K M, Pooley, K A, Eeles, R A, Lee, J E, Fang, S, Chen, W V, Law, M H, Bowdler, L M, Iles, M M, Yang, Q, Worrall, B B, Markus, H S, Hung, R J, Amos, C I, Spurdle, A B, Thompson, D J, O'Mara, T A, Wolpin, B M, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N C, Lund, E, Duell, E J, Canzian, F, Severi, G, Overvad, K, Gunter, M J, Tumino, R, Svenson, U, van Rij, A, Baas, A F, Bown, M J, Samani, N J, van t'Hof, F N G & Telomeres Mendelian Randomization Collaboration 2017, ' Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases : A Mendelian Randomization Study ', JAMA Oncology, vol. 3, no. 5, pp. 636-651 . https://doi.org/10.1001/jamaoncol.2016.5945
Haycock, P C, Burgess, S, Nounu, A, Zheng, J, Okoli, G N, Bowden, J, Wade, K H, Timpson, N J, Evans, D M, Willeit, P, Aviv, A, Gaunt, T R, Hemani, G, Mangino, M, Ellis, H P, Kurian, K M, Pooley, K A, Eeles, R A, Lee, J E, Fang, S, Chen, W V, Law, M H, Bowdler, L M, Iles, M M, Yang, Q, Worrall, B B, Markus, H S, Hung, R J, Amos, C I, Spurdle, A B, Thompson, D J, O'Mara, T A, Wolpin, B, Amundadottir, L, Stolzenberg-Solomon, R, Trichopoulou, A, Onland-Moret, N C, Lund, E, Duell, E J, Canzian, F, Severi, G, Overvad, K, Gunter, M J, Tumino, R, Svenson, U, van Rij, A, Baas, A F, Bown, M J & Albagha, O & Ralston, S H 2017, ' Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases : A Mendelian Randomization Study ', JAMA Oncology, vol. 3, no. 5, pp. 636-651 . https://doi.org/10.1001/jamaoncol.2016.5945
JAMA Oncology, 3(5), 636-651. American Medical Association
Importance The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation. Objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2000a873a3758f4f5146b904102b8d
https://ora.ox.ac.uk/objects/uuid:fa418653-b9ce-4f1f-bc60-a388ffad4b6b
https://ora.ox.ac.uk/objects/uuid:fa418653-b9ce-4f1f-bc60-a388ffad4b6b
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Akademický článek
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Autor:
Cheng, T.H.T., Thompson, D., Painter, J., O'Mara, T., Gorman, M., Martin, L., Palles, C., Jones, A., Buchanan, D.D., Win, A.K., Hopper, J., Jenkins, M., Lindor, N.M., Newcomb, P.A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Giles, G.G., Pharoah, P., Peto, J., Cox, A., Swerdlow, A., Couch, F., Cunningham, J.M., Goode, E.L., Winham, S.J., Lambrechts, D., Fasching, P., Burwinkel, B., Brenner, H., Brauch, H., Chang-Claude, J., Salvesen, H.B., Kristensen, V., Darabi, H., Li, J., Liu, T., Lindblom, A., Hall, P., Echeverry de Polanco, M., Sans, M., Carracedo, A., Castellvi-Bel, S., Rojas-Martinez, A., Jr, A.S., Teixeira, M.R., Dunning, A.M., Dennis, J., Otton, G., Proietto, T., Holliday, E., Attia, J., Ashton, K., Scott, R.J., McEvoy, M., Dowdy, S.C., Fridley, B.L., Werner, H.M.J., Trovik, J., Njolstad, T.S., Tham, E., Mints, M., Runnebaum, I., Hillemanns, P., Doerk, T., Amant, F., Schrauwen, S., Hein, A., Beckmann, M.W., Ekici, A., Czene, K., Meindl, A., Bolla, M.K., Michailidou, K., Tyrer, J.P., Wang, Q., Ahmed, S., Healey, C.S., Shah, M., Annibali, D., Depreeuw, J., Al-Tassan, N.A., Harris, R., Meyer, B.F., Whiffin, N., Hosking, F.J., Kinnersley, B., Farrington, S.M., Timofeeva, M., Tenesa, A., Campbell, H., Haile, R.W., Hodgson, S., Carvajal-Carmona, L., Cheadle, J.P., Easton, D., Dunlop, M., Houlston, R., Spurdle, A., Tomlinson, I.
Publikováno v:
Scientific reports, 5. Nature Publishing Group
Scientific Reports
Cheng, T H, Thompson, D, Painter, J, O'Mara, T, Gorman, M, Martin, L, Palles, C, Jones, A, Buchanan, D D, Ko Win, A, Hopper, J, Jenkins, M, Lindor, N M, Newcomb, P A, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Giles, G G, Pharoah, P, Peto, J, Cox, A, Swerdlow, A, Couch, F, Cunningham, J M, Goode, E L, Winham, S J, Lambrechts, D, Fasching, P, Burwinkel, B, Brenner, H, Brauch, H, Chang-Claude, J, Salvesen, H B, Kristensen, V, Darabi, H, Li, J, Liu, T, Lindblom, A, Hall, P, de Polanco, M E, Sans, M, Carracedo, A, Castellvi-Bel, S, Rojas-Martinez, A, Aguiar Jnr, S, Teixeira, M R, Dunning, A M, Dennis, J, Otton, G, Proietto, T, Holliday, E, Attia, J, Ashton, K, Scott, R J, McEvoy, M, Dowdy, S C, Fridley, B L, Werner, H M, Trovik, J, Njolstad, T S, Tham, E, Mints, M, Runnebaum, I, Hillemanns, P, Dörk, T, Amant, F, Schrauwen, S, Hein, A, Beckmann, M W, Ekici, A, Czene, K, Meindl, A, Bolla, M K, Michailidou, K, Tyrer, J P, Wang, Q, Ahmed, S, Healey, C S, Shah, M, Annibali, D, Depreeuw, J, Al-Tassan, N A, Harris, R, Meyer, B F, Whiffin, N, Hosking, F J, Kinnersley, B, Farrington, S M, Timofeeva, M, Tenesa, A, Campbell, H, Haile, R W, Hodgson, S, Carvajal-Carmona, L, Cheadle, J P, Easton, D, Dunlop, M, Houlston, R, Spurdle, A & Tomlinson, I 2015, ' Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1 ', Scientific Reports, vol. 5, 17369 . https://doi.org/10.1038/srep17369
Scientific Reports
Cheng, T H, Thompson, D, Painter, J, O'Mara, T, Gorman, M, Martin, L, Palles, C, Jones, A, Buchanan, D D, Ko Win, A, Hopper, J, Jenkins, M, Lindor, N M, Newcomb, P A, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Giles, G G, Pharoah, P, Peto, J, Cox, A, Swerdlow, A, Couch, F, Cunningham, J M, Goode, E L, Winham, S J, Lambrechts, D, Fasching, P, Burwinkel, B, Brenner, H, Brauch, H, Chang-Claude, J, Salvesen, H B, Kristensen, V, Darabi, H, Li, J, Liu, T, Lindblom, A, Hall, P, de Polanco, M E, Sans, M, Carracedo, A, Castellvi-Bel, S, Rojas-Martinez, A, Aguiar Jnr, S, Teixeira, M R, Dunning, A M, Dennis, J, Otton, G, Proietto, T, Holliday, E, Attia, J, Ashton, K, Scott, R J, McEvoy, M, Dowdy, S C, Fridley, B L, Werner, H M, Trovik, J, Njolstad, T S, Tham, E, Mints, M, Runnebaum, I, Hillemanns, P, Dörk, T, Amant, F, Schrauwen, S, Hein, A, Beckmann, M W, Ekici, A, Czene, K, Meindl, A, Bolla, M K, Michailidou, K, Tyrer, J P, Wang, Q, Ahmed, S, Healey, C S, Shah, M, Annibali, D, Depreeuw, J, Al-Tassan, N A, Harris, R, Meyer, B F, Whiffin, N, Hosking, F J, Kinnersley, B, Farrington, S M, Timofeeva, M, Tenesa, A, Campbell, H, Haile, R W, Hodgson, S, Carvajal-Carmona, L, Cheadle, J P, Easton, D, Dunlop, M, Houlston, R, Spurdle, A & Tomlinson, I 2015, ' Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1 ', Scientific Reports, vol. 5, 17369 . https://doi.org/10.1038/srep17369
High-risk mutations in several genes predispose to both colorectal cancer (CRC) and endometrial cancer (EC). We therefore hypothesised that some lower-risk genetic variants might also predispose to both CRC and EC. Using CRC and EC genome-wide associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5b75206639aba75ebc46825f9288911c
https://pure.amc.nl/en/publications/metaanalysis-of-genomewide-association-studies-identifies-common-susceptibility-polymorphisms-for-colorectal-and-endometrial-cancer-near-sh2b3-and-tshz1(6d4040ab-1937-4431-9398-05908d4da84c).html
https://pure.amc.nl/en/publications/metaanalysis-of-genomewide-association-studies-identifies-common-susceptibility-polymorphisms-for-colorectal-and-endometrial-cancer-near-sh2b3-and-tshz1(6d4040ab-1937-4431-9398-05908d4da84c).html
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