Dupilumab provides favourable long-term safety and efficacy in children aged ≥ 6 to < 12 years with uncontrolled severe atopic dermatitis: results from an open-label phase IIa study and subsequent phase III open-label extension study

Autor: Cork, MJ, Thaçi, D, Eichenfield, LF, Arkwright, PD, Sun, X, Chen, Z, Akinlade, B, Boklage, S, Guillemin, I, Kosloski, MP, Kamal, MA, O'Malley, JT, Patel, N, Graham, NMH, Bansal, A

Publikováno v: The British journal of dermatology, vol 184, iss 5

BackgroundChildren aged ≥ 6 to < 12 years with severe atopic dermatitis (AD) have limited treatment options. In a 16-week, randomized, placebo-controlled, phase III trial in children, dupilumab, a monoclonal antibody inhibiting interleukin (IL)-4/I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::9cac1e87b16984b369aaaadaef2f4cc0
https://escholarship.org/uc/item/6xq251dw

A growing pigmented lesion in a child with a history of bone marrow transplant and irradiation-quiz case.

Autor: Weitz NA, Tlougan BE, O'Malley JT, Lauren CT, Garzon MC

Publikováno v: Archives of Dermatology; Aug2012, Vol. 148 Issue 8, p947-952, 6p

Pathophysiology of Prurigo Nodularis: Neuroimmune Dysregulation and the Role of Type 2 Inflammation.

Autor: Kwatra SG; Department of Dermatology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Maryland Itch Center, University of Maryland School of Medicine, Baltimore, Maryland, USA., Ständer S; Department of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany., Yosipovitch G; Miami Itch Center, Dr. Philip Frost Department of Dermatology & Cutaneous Surgery, University of Miami, Miami, Florida, USA., Kim BS; Mark Lebwohl Center for Neuroinflammation and Sensation, Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Levit NA; Dermatology Physicians of Connecticut, Fairfield, Connecticut, USA., O'Malley JT; Sanofi, Cambridge, Massachusetts, USA. Electronic address: john.o'malley2@sanofi.com.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2024 Aug 29. Date of Electronic Publication: 2024 Aug 29.

Poly(Ethylene Glycols) to Facilitate Celloidin Removal for Immunohistochemical Studies on Archival Human Brain and Temporal Bone Sections.

Autor: Bächinger D; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland; University of Zurich, Zurich, Switzerland., O'Malley JT; Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear, Boston, Massachusetts.; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts., Wolf M; Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland., Bérnhard S; Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland., Liberman MC; Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear, Boston, Massachusetts.; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts., Tibbitt MW; Macromolecular Engineering Laboratory, Institute of Energy and Process Engineering, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland., Eckhard AH; Otopathology Laboratory, Department of Otolaryngology, Massachusetts Eye and Ear, Boston, Massachusetts.; Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts.

Publikováno v: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society [J Histochem Cytochem] 2024 Jul; Vol. 72 (7), pp. 419-433. Date of Electronic Publication: 2024 Jul 25.

Phototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides.

Autor: Yu Z; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Vieyra-Garcia P; Research Unit for Photodermatology, Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria., Benezeder T; Research Unit for Photodermatology, Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria., Crouch JD; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kim IR; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., O'Malley JT; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Devlin PM; Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts, USA., Gehad A; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Zhan Q; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Gudjonsson JE; Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA., Sarkar MK; Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA., Kahlenberg JM; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Gerard N; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Teague JE; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kupper TS; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Center for Cutaneous Oncology, Dana-Farber Cancer Institute/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts, USA., LeBoeuf NR; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Center for Cutaneous Oncology, Dana-Farber Cancer Institute/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts, USA., Larocca C; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Center for Cutaneous Oncology, Dana-Farber Cancer Institute/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts, USA., Tawa M; Center for Cutaneous Oncology, Dana-Farber Cancer Institute/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts, USA., Pomahac B; Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA., Talbot SG; Division of Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Orgill DP; Division of Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Wolf P; Research Unit for Photodermatology, Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria. Electronic address: peter.wolf@medunigraz.at., Clark RA; Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: rclark@bwh.harvard.edu.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2024 Mar; Vol. 144 (3), pp. 621-632.e1. Date of Electronic Publication: 2023 Sep 15.