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Akademický článek
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Akademický článek
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Autor:
McSherry Lisa A, Dombrowski Stephan U, Francis Jill J, Murphy Judith, Martin Cara M, O’Leary John J, Sharp Linda
Publikováno v:
Implementation Science, Vol 7, Iss 1, p 73 (2012)
Abstract Background The relationship between infection with high-risk human papillomavirus (HPV) and cervical cancer is transforming cervical cancer prevention. HPV tests and vaccinations have recently become available. In Ireland, as elsewhere, prim
Externí odkaz:
https://doaj.org/article/ae22d15118d547a19b1e37e7ce082e88
Autor:
Gallagher Michael F, Heffron Cynthia CBB, Laios Alexandros, O'Toole Sharon A, Ffrench Brendan, Smyth Paul C, Flavin Richard J, Elbaruni Salah A, Spillane Cathy D, Martin Cara M, Sheils Orla M, O'Leary John J
Publikováno v:
Journal of Ovarian Research, Vol 5, Iss 1, p 2 (2012)
Abstract Background Malignant ovarian disease is characterised by high rates of mortality due to high rates of recurrent chemoresistant disease. Anecdotal evidence indicates this may be due to chemoresistant properties of cancer stem cells (CSCs). Ho
Externí odkaz:
https://doaj.org/article/25684533327049feab4c31d487d25546
Autor:
Abisambra Jose F, Peters Melinda, Kraft Clara, Jones Jeffrey R, Koren John, Jinwal Umesh K, Johnson Amelia G, Congdon Erin E, Blair Laura J, Marinec Paul, Li Qingyou, O'Leary John C, Duff Karen E, Weeber Edwin J, Gestwicki Jason E, Dickey Chad A
Publikováno v:
Molecular Neurodegeneration, Vol 5, Iss 1, p 45 (2010)
Abstract Background It has traditionally been thought that the pathological accumulation of tau in Alzheimer's disease and other tauopathies facilitates neurodegeneration, which in turn leads to cognitive impairment. However, recent evidence suggests
Externí odkaz:
https://doaj.org/article/a278319ae4704e5a8526dd27afba4ede
Autor:
Gallagher Michael F, Flavin Richard J, Elbaruni Salah A, McInerney Jamie K, Smyth Paul C, Salley Yvonne M, Vencken Sebastian F, O'Toole Sharon A, Laios Alexandros, Lee Mathia YC, Denning Karen, Li Jinghuan, Aherne Sinead T, Lao Kai Q, Martin Cara M, Sheils Orla M, O'Leary John J
Publikováno v:
Journal of Ovarian Research, Vol 2, Iss 1, p 19 (2009)
Abstract Background Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells. This property may be linked to the differentiation properties of stem cell
Externí odkaz:
https://doaj.org/article/94d9c4f9b4a74aa886b21e5182b624fd
Autor:
Li Jing, Denning Karen M, Russell Susan M, Flavin Richard J, Smyth Paul C, Aherne Sinéad T, Guenther Simone M, O'Leary John J, Sheils Orla M
Publikováno v:
Molecular Cancer, Vol 7, Iss 1, p 89 (2008)
Abstract Background Papillary thyroid carcinoma (PTC) frequently presents as multiple tumour-foci within a single thyroid gland or pluriform, with synchronous tumours comprising different histological variants, raising questions regarding its clonali
Externí odkaz:
https://doaj.org/article/980f6cd24a16437ebc92a08021584c0c
Autor:
Pirotta Marco, Aherne Sinead, Flavin Richard, Denning Karen, Cahill Susanne, Smyth Paul, Li Jinghuan, Guenther Simone M, O'Leary John J, Sheils Orla
Publikováno v:
BMC Biotechnology, Vol 8, Iss 1, p 10 (2008)
Abstract Background Archival formalin-fixed paraffin-embedded (FFPE) tissues represent an abundant source of clinical specimens; however their use is limited in applications involving analysis of gene expression due to RNA degradation and modificatio
Externí odkaz:
https://doaj.org/article/9579d75747114fd19206bd752a0aefd4
Autor:
Guenther Simone M, Aherne Sinead, Denning Karen, Cahill Susanne, Flavin Richard, Smyth Paul, Li Jinghuan, O'Leary John J, Sheils Orla
Publikováno v:
BMC Biotechnology, Vol 7, Iss 1, p 36 (2007)
Abstract Background Archival formalin-fixed paraffin-embedded (FFPE) tissues have limited utility in applications involving analysis of gene expression due to mRNA degradation and modification during fixation and processing. This study analyzed 160 m
Externí odkaz:
https://doaj.org/article/a8be3fabb105440ba533771476de5f34
Autor:
Guenther Simone M, Potratz Astrid, Li Jinghuan, Flavin Richard, Denning Karen, Smyth Paul, Cahill Susanne, Henfrey Richard, O'Leary John J, Sheils Orla
Publikováno v:
Molecular Cancer, Vol 6, Iss 1, p 21 (2007)
Abstract Background microRNAs (miRNAs) are a group of non-coding single stranded RNAs measuring approximately 22 nucleotides in length that have been found to control cell growth, differentiation and apoptosis. They negatively regulate target genes a
Externí odkaz:
https://doaj.org/article/13ea57d3122b4aa1ace70f48ad172b77