Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids.

Autor: Kjar A; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Haschert MR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Zepeda JC; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA., Simmons AJ; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Yates A; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA., Chavarria D; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Fernandez M; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Robertson G; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Abdulrahman AM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Kim H; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Marguerite NT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Moen RK; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Drake LE; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Curry CW; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., O'Grady BJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Gama V; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA., Lau KS; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA; Chemical and Physical Biology Program, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Grueter B; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA; Department of Anesthesiology, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA., Brunger JM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Lippmann ES; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: ethan.s.lippmann@vanderbilt.edu.

Publikováno v: Cell reports [Cell Rep] 2024 Oct 17; Vol. 43 (11), pp. 114874. Date of Electronic Publication: 2024 Oct 17.

Growth factor free, peptide-functionalized gelatin hydrogel promotes arteriogenesis and attenuates tissue damage in a murine model of critical limb ischemia.

Autor: Curry CW; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Sturgeon SM; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., O'Grady BJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Yates A; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA., Kjar A; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Paige H; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Mowery LS; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Katdare KA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA., Patel R; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Mlouk K; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA., Stiefbold MR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Vafaie-Partin S; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Kawabata A; Department of Orthopedics, Vanderbilt University Medical Center, Nashville, TN, USA., McKee R; Department of Orthopedics, Vanderbilt University Medical Center, Nashville, TN, USA., Moore-Lotridge S; Department of Orthopedics, Vanderbilt University Medical Center, Nashville, TN, USA., Hawkes A; Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA., Kusunose J; Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA., Gibson-Corley KN; Department of Pathology, Microbiology and Immunology, Division of Comparative Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Schmeckpeper J; Department of Cardiology, Vanderbilt University Medical Center, Nashville, TN, USA., Schoenecker JG; Department of Orthopedics, Vanderbilt University Medical Center, Nashville, TN, USA., Caskey CF; Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA., Lippmann ES; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA. Electronic address: ethan.s.lippmann@vanderbilt.edu.

Publikováno v: Biomaterials [Biomaterials] 2023 Dec; Vol. 303, pp. 122397. Date of Electronic Publication: 2023 Nov 13.

Rapid prototyping of cell culture microdevices using parylene-coated 3D prints.

Autor: O'Grady BJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu., Geuy MD; Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, Nashville, TN, USA., Kim H; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu., Balotin KM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Allchin ER; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu., Florian DC; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Bute NN; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA., Scott TE; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu., Lowen GB; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu., Fricker CM; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA., Fitzgerald ML; Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, USA., Guelcher SA; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu., Wikswo JP; Vanderbilt Institute for Integrative Biosystems Research and Education, Vanderbilt University, Nashville, TN, USA.; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.; Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Bellan LM; Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, USA.; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA., Lippmann ES; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA. brian.ogrady@vanderbilt.edu.; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA.

Publikováno v: Lab on a chip [Lab Chip] 2021 Dec 07; Vol. 21 (24), pp. 4814-4822. Date of Electronic Publication: 2021 Dec 07.

Development of an N-Cadherin Biofunctionalized Hydrogel to Support the Formation of Synaptically Connected Neural Networks.

Autor: O'Grady BJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, Tennessee 37235, United States., Balotin KM; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Bosworth AM; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., McClatchey PM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37235, United States., Weinstein RM; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Gupta M; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Poole KS; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Bellan LM; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Mechanical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States., Lippmann ES; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee 37235, United States.; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.

Publikováno v: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2020 Oct 12; Vol. 6 (10), pp. 5811-5822. Date of Electronic Publication: 2020 Sep 04.

Spatiotemporal Control of Morphogen Delivery to Pattern Stem Cell Differentiation in Three-Dimensional Hydrogels.

Autor: O'Grady BJ; Department of Mechanical Engineering, Vanderbilt University, Nashville, Tennessee.; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, Tennessee., Balikov DA; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee.; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee., Lippmann ES; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee.; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee., Bellan LM; Department of Mechanical Engineering, Vanderbilt University, Nashville, Tennessee.; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, Tennessee.; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee.

Publikováno v: Current protocols in stem cell biology [Curr Protoc Stem Cell Biol] 2019 Dec; Vol. 51 (1), pp. e97.