AAV2/8 Anti-angiogenic Gene Therapy Using Single-Chain Antibodies Inhibits Murine Choroidal Neovascularization.

Autor: Hughes CP; Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK., O'Flynn NMJ; Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK., Gatherer M; Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK., McClements ME; Oxford Eye Hospital and Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Scott JA; Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK., MacLaren RE; Oxford Eye Hospital and Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Goverdhan S; Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK., Glennie MJ; Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Lotery AJ; Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2018 Nov 22; Vol. 13, pp. 86-98. Date of Electronic Publication: 2018 Nov 22 (Print Publication: 2019).