Influence of propofol on isolated neonatal rat carotid body glomus cell response to hypoxia and hypercapnia

Autor: O'Donohoe, PB, Turner, PJ, Huskens, N, Buckler, KJ, Pandit, JJ

Publikováno v: Respiratory Physiology & Neurobiology

Highlights • The intravenous anaesthetic propofol acts directly on carotid body glomus cells to inhibit their response to hypoxia. • Propofol acts via novel mechanisms, as we excluded action via its known target receptors (nicotinic, GABA-ergic,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d3c34d3fbd04429e2754f7cf835bdeea
https://pubmed.ncbi.nlm.nih.gov/30389452

Lack of influence of dexmedetomidine on rat glomus cell response to hypoxia, and on mouse acute hypoxic ventilatory response.

Autor: O'Donohoe PB; Department of Physiology, Anatomy and Genetics, Parks Road, Oxford OX1 3PT, UK.; Nuffield Department of Anaesthetics, Oxford University Hospitals, Oxford OX3 9DU, UK., Turner PJ; Department of Physiology, Anatomy and Genetics, Parks Road, Oxford OX1 3PT, UK., Huskens N; Department of Physiology, Anatomy and Genetics, Parks Road, Oxford OX1 3PT, UK., Buckler KJ; Department of Physiology, Anatomy and Genetics, Parks Road, Oxford OX1 3PT, UK., Pandit JJ; Nuffield Department of Anaesthetics, Oxford University Hospitals, Oxford OX3 9DU, UK.

Publikováno v: Journal of anaesthesiology, clinical pharmacology [J Anaesthesiol Clin Pharmacol] 2021 Oct-Dec; Vol. 37 (4), pp. 509-516. Date of Electronic Publication: 2022 Jan 06.

Influence of propofol on isolated neonatal rat carotid body glomus cell response to hypoxia and hypercapnia.

Autor: O'Donohoe PB; Department of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK; Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Trust, Oxford, OX3 9DU, UK., Turner PJ; Department of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK., Huskens N; Department of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK., Buckler KJ; Department of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK., Pandit JJ; Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Trust, Oxford, OX3 9DU, UK. Electronic address: jaideep.pandit@dpag.ox.ac.uk.

Publikováno v: Respiratory physiology & neurobiology [Respir Physiol Neurobiol] 2019 Feb; Vol. 260, pp. 17-27. Date of Electronic Publication: 2018 Oct 30.

Exploring the clinical utility of blood ketone levels in the emergency department assessment of paediatric patients.

Autor: O'Donohoe PB; College of Medicine, University of Edinburgh, Edinburgh, UK. p_od@yahoo.com, Kessler R, Beattie TF

Publikováno v: Emergency medicine journal : EMJ [Emerg Med J] 2006 Oct; Vol. 23 (10), pp. 783-7.