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Real-world experience with obeticholic acid in patients with primary biliary cholangitis

Autor: Anna Morgando, Mauro Viganò, Ana Lleo, Maurizio Pompili, Elisabetta De Gasperi, Daphne D’Amato, Alessandro Mussetto, Nora Cazzagon, Pietro Invernizzi, Francesca Colapietro, Vincenzo Ronca, Sara Labanca, Ester Vanni, M.R. Cannavò, Francesco Losito, Ernesto Claar, G. Scifo, Giovanni Galati, Umberto Vespasiani-Gentilucci, Silvia Storato, Alessio Gerussi, Grazia Anna Niro, Antonio Izzi, Barbara Omazzi, Antonio De Vincentis, Valentina Feletti, Giuseppe Grassi, Valeria Pace Palitti, Clara Mancuso, Vincenza Calvaruso, Evelise Frazzetto, Roberto Boldizzoni, Marco Marzioni, Floriano Rosina, Andrea Palermo, Antonino Picciotto, Valentina Bellia, Gaetano Bertino, Italian Pbc Registry, Guido Poggi, Rodolfo Sacco, Domenico Alvaro, Luigi Muratori, Maria Vinci, Marie Graciella Pigozzi, Raffaele Cozzolongo, Natalia Terreni, Annarosa Floreani, Maurizio Russello, Marco Distefano, Rinaldo Pellicano, Maria D'Antò, Marco Carbone, Rosanna Venere, R. Fontana, Antonio Picardi, Silvia Casella, S. E. O'Donnell, Federica Malinverno, Stefano Fagiuoli, Laura Cristoferi, Luchino Chessa, Giacomo Mulinacci, Pietro Pozzoni, Antonino Castellaneta, Giulia Marconi, Adriano M. Pellicelli, Francesca Romana Ponziani, Leonardo Baiocchi

Publikováno v: JHEP Reports, Vol 3, Iss 2, Pp 100248-(2021)
JHEP Reports

Background & aims Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to ursodeoxycholic acid. We aimed to evaluate the effectiveness and safety of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fe7d019f05517ffe25526686712b24
http://hdl.handle.net/20.500.11769/503362

Real-world experience with obeticholic acid in patients with primary biliary cholangitis.

Autor: D'Amato D; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., De Vincentis A; Internal Medicine and Hepatology, University Campus Bio-Medico of Rome, Rome, Italy., Malinverno F; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Viganò M; Hepatology Unit, San Giuseppe Hospital, Milan, Italy., Alvaro D; Department of Translational and Precision Medicine, University La Sapienza, Rome, Italy., Pompili M; Internal Medicine and Hepatology Unit, Policlinico Gemelli, Sapienza University, Rome, Italy., Picciotto A; Clinic of Gastroenterology, San Martino Hospital, Genoa, Italy., Palitti VP; Hepatology Unit, Santo Spirito Hospital, Pescara, Italy., Russello M; Liver Unit, Arnas Garibaldi, Catania, Italy., Storato S; IRCCS Sacro Cuore Institute Don Calabria, Gastroenterology, Negrar, Italy., Pigozzi MG; Gastroenterology Unit, Spedali Civili Hospital, Brescia, Italy., Calvaruso V; Gastroenterology and Hepatology Unit, University of Palermo, Palermo, Italy., De Gasperi E; Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico - Division of Gastroenterology and Hepatology - CRC 'A.M. and A. Migliavacca' Center for Liver Disease, Milan, Italy., Lleo A; Internal Medicine and Hepatology, Humanitas Clinical and Research Center IRCCS, Humanitas University, Milan, Italy., Castellaneta A; Gastroenterology Unit, Policlinico di Bari Hospital, Bari, Italy., Pellicelli A; Liver Unit, San Camillo Hospital, Rome, Italy., Cazzagon N; Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy., Floreani A; Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology, Padua University Hospital, Padua, Italy., Muratori L; DIMEC Università di Bologna, Policlinico di Sant'Orsola, Via Massarenti 9, 40138, Bologna, Italy., Fagiuoli S; Hepatology and Liver Transplant Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy., Niro GA; Gastroenterology Unit, Fondazione Casa Sollievo Della Sofferenza IRCCS, San Giovanni Rotondo, Foggia, Italy., Feletti V; Gastroenterology Unit, Santa Maria Delle Croci Hospital, Ravenna, Italy., Cozzolongo R; Gastroenterology Unit, National Institute of Gastroenterology 'S de Bellis' Research Hospital, Castellana Grotte, Bari, Italy., Terreni N; Hepatology Unit, Valduce Hospital, Como, Italy., Marzioni M; Clinic of Gastroenterology and Hepatology, Università Politecnica delle Marche, Ancona, Italy., Pellicano R; Gastroenterology Unit, Città della salute e della scienza, Turin, Italy., Pozzoni P; Hepatology Unit, Alessandro Manzoni Hospital, Lecco, Italy., Baiocchi L; Hepatology Unit, University of Rome 'Tor Vergata', Rome, Italy., Chessa L; Liver Unit, University Hospital of Cagliari, Cagliari, Italy., Rosina F; Medical Team Torino, Turin, Italy., Bertino G; Gastroenterology and Hepatology Unit, University Hospital Policlinico Vittorio Emanuele, Catania, Italy., Vinci M; Hepatology Unit, Niguarda Hospital, Milan, Italy., Morgando A; Gastroenterology Unit, Città della salute e della scienza, Turin, Italy., Vanni E; Gastroenterology Unit, Città della salute e della scienza, Turin, Italy., Scifo G; Department of Infectious Diseases, Umberto I Hospital, Syracuse, Italy., Sacco R; Gastroenterology Unit, Ospedali Riuniti, Foggia, Italy., D'Antò M; Hepatology Unit, Santa Maria delle Grazie Hospital, Pozzuoli, Italy., Bellia V; Hepatology Unit, Valtellina e Alto Lario Hospital, Sondrio, Italy., Boldizzoni R; Hepatology Unit, Treviglio Caravaggio Hospital, Treviglio, Italy., Casella S; Hepatology Unit, Spedali Civili Gardone Val Trompia, Brescia, Italy., Omazzi B; Gastroenterology Unit, Guido Salvini Hospital, Rho, Italy., Poggi G; Oncology Unit, Istituto di Cura Città di Pavia, Pavia, Italy., Cristoferi L; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Gerussi A; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Ronca V; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Venere R; Department of Translational and Precision Medicine, University La Sapienza, Rome, Italy., Ponziani F; Internal Medicine and Hepatology Unit, Policlinico Gemelli, Sapienza University, Rome, Italy., Cannavò M; Liver Unit, Arnas Garibaldi, Catania, Italy., Mussetto A; Gastroenterology Unit, Santa Maria Delle Croci Hospital, Ravenna, Italy., Fontana R; Gastroenterology Unit, Fondazione Casa Sollievo Della Sofferenza IRCCS, San Giovanni Rotondo, Foggia, Italy., Losito F; Gastroenterology Unit, National Institute of Gastroenterology 'S de Bellis' Research Hospital, Castellana Grotte, Bari, Italy., Frazzetto E; Gastroenterology and Hepatology Unit, University Hospital Policlinico Vittorio Emanuele, Catania, Italy., Distefano M; Department of Infectious Diseases, Umberto I Hospital, Syracuse, Italy., Colapietro F; Internal Medicine and Hepatology, Humanitas Clinical and Research Center IRCCS, Humanitas University, Milan, Italy., Labanca S; Clinic of Gastroenterology, San Martino Hospital, Genoa, Italy., Marconi G; Clinic of Gastroenterology and Hepatology, Università Politecnica delle Marche, Ancona, Italy., Grassi G; Hepatology Unit, University of Rome 'Tor Vergata', Rome, Italy., Galati G; Internal Medicine and Hepatology, University Campus Bio-Medico of Rome, Rome, Italy., O'Donnell SE; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Mancuso C; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Mulinacci G; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Palermo A; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Claar E; Hepatology Unit, Betania Hospital, Naples, Italy., Izzi A; Department of Infectious Diseases, D. Cotugno Hospital, Naples, Italy., Picardi A; Internal Medicine and Hepatology, University Campus Bio-Medico of Rome, Rome, Italy., Invernizzi P; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Carbone M; Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy., Vespasiani-Gentilucci U; Internal Medicine and Hepatology, University Campus Bio-Medico of Rome, Rome, Italy.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2021 Jan 27; Vol. 3 (2), pp. 100248. Date of Electronic Publication: 2021 Jan 27 (Print Publication: 2021).

Ciprofloxacin prophylaxis is associated with a lower incidence of gram-negative bacteremia in patients undergoing allogeneic hematopoietic cell transplantation.

Autor: Maurer AK; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Li S; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Hunter BD; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., Luk SO; Department of Pharmacy, Massachusetts General Hospital, Boston, MA, USA., O'Donnell SE; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., Dey BR; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., El-Jawahri A; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., Frigault MJ; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., McAfee S; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., O'Donnell PV; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., Spitzer TR; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., Chen YB; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA., DeFilipp Z; Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA, USA. zdefilipp@mgh.harvard.edu.

Publikováno v: Bone marrow transplantation [Bone Marrow Transplant] 2020 Dec; Vol. 55 (12), pp. 2319-2321. Date of Electronic Publication: 2020 May 26.