CSF1-R inhibition attenuates posttraumatic osteoarthritis and quadriceps atrophy following ligament injury.

Autor: Keeble AR; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, USA., Thomas NT; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Balawender PJ; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA., Brightwell CR; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Gonzalez-Velez S; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, KY, USA., O'Daniel MG; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA., Conley CE; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Stone AV; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Johnson DL; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA., Noehren B; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Jacobs CA; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.; Mass General Brigham Sports Medicine, Harvard Medical School, Boston, MA, USA., Fry CS; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, KY, USA., Owen AM; Center for Muscle Biology, University of Kentucky, Lexington, KY, USA.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, KY, USA.

Publikováno v: The Journal of physiology [J Physiol] 2024 Dec 22. Date of Electronic Publication: 2024 Dec 22.