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Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae

Autor: Sean Timothy Francis O'Connor, Jiaqi eLan, Matthew eNorth, Alexandre eLoguinov, Luoping eZhang, Martyn T Smith, April eGu, Chris eVulpe

Publikováno v: O'Connor, Sean Timothy Francis; Lan, Jiaqi; North, Matthew; Loguinov, Alexandre; Zhang, Luoping; Smith, Martyn T; et al.(2013). Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae. Frontiers in Genetics, 3. doi: 10.3389/fgene.2012.00316. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/69s8908n
Frontiers in Genetics
Frontiers in Genetics, Vol 3 (2013)

Benzo[a]pyrene (BaP) is a ubiquitous, potent, and complete carcinogen resulting from incomplete organic combustion. BaP can form DNA adducts but other mechanisms may play a role in toxicity. We used a functional toxicology approach in S. cerevisiae t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8634b47b63b172fba4c88e3a64554b02
http://www.escholarship.org/uc/item/69s8908n