Breast cancer-secreted miR-122 reprograms glucose metabolism in pre-metastatic niche to promote metastasis

Autor: Fong, Miranda Y., Zhou, Weiying, Liu, Liang, Alontaga, Aileen Y., Chandra, Manasa, Ashby, Jonathan, Chow, Amy, O’Connor, Sean Francis, Li, Shasha, Chin, Andrew R., Somlo, George, Palomares, Melanie, Li, Zhuo, Tremblay, Jacob R., Tsuyada, Akihiro, Sun, Guoqiang, Reid, Michael A., Wu, Xiwei, Swiderski, Piotr, Ren, Xiubao, Shi, Yanhong, Kong, Mei, Zhong, Wenwan, Chen, Yuan, Wang, Shizhen Emily

Publikováno v: Fong, Miranda Y.; Zhou, Weiying; Liu, Liang; Alontaga, Aileen Y.; Chandra, Manasa; Ashby, Jonathan; et al.(2015). Breast cancer-secreted miR-122 reprograms glucose metabolism in pre-metastatic niche to promote metastasis. Nature cell biology, 17(2), 183-194. UC Office of the President: California Breast Cancer Research Program. Retrieved from: http://www.escholarship.org/uc/item/3sg6m9qp

Reprogrammed glucose metabolism as a result of increased glycolysis and glucose uptake is a hallmark of cancer. Here we show that cancer cells can suppress glucose uptake by non-tumour cells in the pre-metastatic niche, by secreting vesicles that car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::b892df65f80624d7c9d154966b7aabd6
http://www.escholarship.org/uc/item/3sg6m9qp