Zobrazeno 1 - 10 of 33 pro vyhledávání: '"O'Brien Cox A"'
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Akademický článek
Regulation of local GTP availability controls RAC1 activity and cell invasion
Autor: Anna Bianchi-Smiraglia, David W. Wolff, Daniel J. Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M. Wombacher, Ashley L. Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O’Brien Cox, Cristina M. Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J. Sousa, Mikhail E. Kandel, Eugene S. Kandel, Klaus M. Hahn, Mikhail A. Nikiforov
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Changes in intracellular GTP levels are not considered as a regulatory event in RAC1 activation in live cells since total GTP levels are substantially higher than the RAC1 GTP dissociation constant determined in vitro. Here, the authors demonstrate t
Externí odkaz: https://doaj.org/article/8aee079d643942f4a47c971818bffc85
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3
Akademický článek
Early [18]FDG PET/CT scan predicts tumor response in head and neck squamous cell cancer patients treated with erlotinib adjusted per smoking status
Autor: Mercedes Porosnicu, Anderson O’Brien Cox, Joshua D. Waltonen, Paul M. Bunch, Ralph D’Agostino, Thomas W. Lycan, Richard Taylor, Dan W. Williams, Xiaofei Chen, Kirtikar Shukla, Brian E. Kouri, Tiffany Walker, Gregory Kucera, Hafiz S. Patwa, Christopher A. Sullivan, J. Dale Browne, Cristina M. Furdui
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
Translational RelevanceEvaluation of targeted therapies is urgently needed for the majority of patients with metastatic/recurrent head and neck squamous cell carcinoma (HNSCC) who progress after immunochemotherapy. Erlotinib, a targeted inhibitor of
Externí odkaz: https://doaj.org/article/c47f8d45cae64e029522153138412aa9
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4
Akademický článek
Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model
Autor: Hannah M. Atkins, Manish S. Bharadwaj, Anderson O’Brien Cox, Cristina M. Furdui, Susan E. Appt, David L. Caudell
Publikováno v: Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Endometriosis is the growth of uterine lining (endometrium) outside of the uterus. In other chronic inflammatory diseases, mitochondrial dysfunction is suspected of playing a role in disease pathogenesis. However, little is known
Externí odkaz: https://doaj.org/article/4648f2c735814ece9f314f22dc60089d
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6
Amino acid supplementation confers protection to red blood cells prior to Plasmodium falciparum bystander stress
Autor: Heather Colvin Binns, Elmira Alipour, Dinah S. Nahid, John F. Whitesides, Anderson O’Brien Cox, Cristina M. Furdui, Glen S. Marrs, Daniel B. Kim-Shapiro, Regina Joice Cordy
Publikováno v: bioRxiv
Malaria is a highly oxidative parasitic disease in which anemia is the most common clinical symptom. A major contributor to malarial anemia pathogenesis is the destruction of bystander, uninfected red blood cells. Metabolic fluctuations are known to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e6ccc7e880953bf84a27b509652c65
https://europepmc.org/articles/PMC10245693/
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7
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice
Autor: Mary Seramur, Sandy Sink, Anderson O’Brien Cox, Cristina M. Furdui, Chia-Chi Chuang Key
Alpha/beta hydrolase domain-containing protein 4 (ABHD4) catalyzes the deacylation ofN-acyl phosphatidyl-ethanolamine (NAPE) and Lyso-NAPE to produce Glycerophospho-N-acyl ethanolamine (GP-NAE). Through a variety of metabolic enzymes, NAPE, Lyso-NAPE
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13b9999bc524270e1f8c6e2ccab2649a
https://doi.org/10.1101/2022.11.29.518076
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8
An Overview of Online Resources for Medical Spanish Education for Effective Communication with Spanish-Speaking Patients
Autor: Kyle C. Kim, Leticia Rolón, Carmen Pérez-Muñoz, Rocio Chang, Daniel Truesdale, Karol J. Hardin, Alyssia M. Miller De Rutté, Cristina Pérez-Cordón, Pilar Ortega, Glenn A. Martínez, Tiffany M Shin, Anderson O’Brien Cox
Publikováno v: Teaching and Learning in Medicine. 34:481-493
Despite the rapid development of virtual medical Spanish educational materials, online resources lack transparency and a peer-review process. The purpose of this interdisciplinary study was to provide a critical inventory of virtual resources for med
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1030718f29de49d11dd8aabdd2205e
https://doi.org/10.1080/10401334.2021.1959335
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10
Regulation of local GTP availability controls RAC1 activity and cell invasion
Autor: Klaus M. Hahn, Shichen Shen, Jules Berlin Nde Kengne, Rebecca M. Wombacher, Anna Bianchi-Smiraglia, Mikhail A. Nikiforov, Jun Qu, Zhiyong Deng, Daniel J. Marston, Eugene S. Kandel, Zhannan Han, Cristina M. Furdui, Bernard Fongang, Dong Hyun Yun, Mikhail E. Kandel, Edward Hurley, Maria Laura Feltri, Anderson O’Brien Cox, Ashley L. Mussell, Jialin Chen, Thomas Hollis, Sudha Moparthy, David W. Wolff, Rui J Sousa
Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Physiological changes in GTP levels in live cells have never been considered a regulatory step of RAC1 activation because intracellular GTP concentration (determined by chromatography or mass spectrometry) was shown to be substantially higher than th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbb06e57d207fc15afead7eab17e0a9
http://europepmc.org/articles/PMC8526568
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