PD-1 blockade enhances chemotherapy toxicity in oesophageal adenocarcinoma.

Autor: Davern M; Cancer Immunology and Immunotherapy Group, Department of Surgery, Trinity Translational Medicine Institute and Trinity St. James's Cancer Institute, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland., O' Brien RM; Translational Radiobiology and Diagnostics Group, Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Dublin 8, Ireland., McGrath J; Translational Radiobiology and Diagnostics Group, Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Dublin 8, Ireland., Donlon NE; Cancer Immunology and Immunotherapy Group, Department of Surgery, Trinity Translational Medicine Institute and Trinity St. James's Cancer Institute, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland., Melo AM; Cancer Immunology and Immunotherapy Group, Department of Surgery, Trinity Translational Medicine Institute and Trinity St. James's Cancer Institute, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland., Buckley CE; Translational Radiobiology and Diagnostics Group, Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Dublin 8, Ireland., Sheppard AD; Cancer Immunology and Immunotherapy Group, Department of Surgery, Trinity Translational Medicine Institute and Trinity St. James's Cancer Institute, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland., Reynolds JV; Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland., Lynam-Lennon N; Translational Radiobiology and Diagnostics Group, Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Dublin 8, Ireland., Maher SG; Cancer Chemoradiation Group, Department of Surgery, Trinity Translational Medicine Institute, St. James's Hospital, Dublin 8, Ireland., Lysaght J; Cancer Immunology and Immunotherapy Group, Department of Surgery, Trinity Translational Medicine Institute and Trinity St. James's Cancer Institute, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland. jlysaght@tcd.ie.

Publikováno v: Scientific reports [Sci Rep] 2022 Feb 28; Vol. 12 (1), pp. 3259. Date of Electronic Publication: 2022 Feb 28.