Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nyosha Alikhani"'
The activated RAS/RAF cascade plays a crucial role in lung cancer, but is also known to induce cellular senescence, a major barrier imposed on tumor cells early in tumorigenesis. MYC is a key factor in suppression of RAS/BRAFV600E-induced senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158e5a702d7d5ef9332cf00610bbd5be
https://doi.org/10.1158/0008-5472.c.6505656
https://doi.org/10.1158/0008-5472.c.6505656
PDF file - 6250K, Activation of BRAFV600E and MYC by Ad-Cre and TAM results in development of SPC-expressing lung tumors. Genomic status after Cre-mediated recombination, MycER protein expression, mouse lung to body weight and expression of different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ecdb9cb666936ac2b42c5dbdde936b
https://doi.org/10.1158/0008-5472.22400748
https://doi.org/10.1158/0008-5472.22400748
PDF file - 152K, Analysis of senescence, apoptosis and p19Arf expression in lung tissues of BRAF/MYC mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90bda0488c8193efc820bee1d0a516b
https://doi.org/10.1158/0008-5472.22400745.v1
https://doi.org/10.1158/0008-5472.22400745.v1
PDF file - 1861K, Lung weights of BRAF/MYC mice early in disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ec9753641aa615aec4111a5019c017
https://doi.org/10.1158/0008-5472.22400742.v1
https://doi.org/10.1158/0008-5472.22400742.v1
Autor:
Nyosha Alikhani, Derek LeRoith, Shoshana Yakar, Rosalyn D. Ferguson, Eyal J. Scheinman, Ruslan Novosyadlyy, Emily J. Gallagher
Publikováno v:
Oncogene. 32:961-967
Dyslipidemia has been associated with an increased risk for developing cancer. However, the implicated mechanisms are largely unknown. To explore the role of dyslipidemia in breast cancer growth and metastasis, we used the apolipoprotein E (ApoE) kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9084c65a9b5714d9a16c2d88e52a37c3
https://doi.org/10.1038/onc.2012.113
https://doi.org/10.1038/onc.2012.113
Autor:
John Xi Chen, Catarina Moreira Pinho, Elzbieta Glaser, Lan Guo, Heng Du, Shirley ShiDu Yan, Shiqiang Yan, Nyosha Alikhani
Publikováno v:
Journal of Alzheimer's Disease. 27:75-87
Accumulation of amyloid-β peptide (Aβ), the neurotoxic peptide implicated in the pathogenesis of Alzheimer's disease (AD), has been shown in brain mitochondria of AD patients and of AD transgenic mouse models. The presence of Aβ in mitochondria le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8234319f95f4907c3b8ba57443debd7a
https://doi.org/10.3233/jad-2011-101716
https://doi.org/10.3233/jad-2011-101716
Autor:
Tanja Engmann, Erika Spånning, Nyosha Alikhani, Elzbieta Glaser, Pavel F. Pavlov, F-Nora Vögtle, Chris Meisinger, Thomas Langer, Anna-Karin Berglund
Publikováno v:
J Mol Biol
Mitochondrial presequences and other unstructured peptides are degraded inside mitochondria by presequence proteases (PrePs) identified in Arabidopsis thaliana (AtPreP), humans (hPreP), and yeast (Cym1/Mop112). The presequences of A. thaliana and hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91ffcc626b2ea79cefc8c46bcff9ec6
https://doi.org/10.1016/j.jmb.2011.05.009
https://doi.org/10.1016/j.jmb.2011.05.009
Autor:
Elzbieta Glaser, Nyosha Alikhani
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797(6-7):1076-1080
The novel peptidasome, called presequence protease, PreP, was originally identified and characterized in Arabidopsis thaliana as a mitochondrial matrix and chloroplast stroma localized metalloprotease. PreP has a function as the organellar peptide cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18e204150d38748051dab5df10a42d3
Publikováno v:
Cancer research. 74(16)
The activated RAS/RAF cascade plays a crucial role in lung cancer, but is also known to induce cellular senescence, a major barrier imposed on tumor cells early in tumorigenesis. MYC is a key factor in suppression of RAS/BRAFV600E-induced senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2df3e77e522d147fbdb3751c7ed912f
https://pubmed.ncbi.nlm.nih.gov/24934810
https://pubmed.ncbi.nlm.nih.gov/24934810
Autor:
Aviva Tobin-Hess, Rosalyn D. Ferguson, Nyosha Alikhani, Derek LeRoith, Emily J. Gallagher, Ruslan Novosyadlyy, Dara Hope Cohen, Nadine Haddad, Shoshana Yakar
Publikováno v:
Endocrine-related cancer. 20(3)
The Her2 oncogene is expressed in ∼25% of human breast cancers and is associated with metastatic progression and poor outcome. Epidemiological studies report that breast cancer incidence and mortality rates are higher in women with type 2 diabetes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d451ca8a03f31db68d2498a8ae58723d
https://pubmed.ncbi.nlm.nih.gov/23572162
https://pubmed.ncbi.nlm.nih.gov/23572162