Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nyeemah Grazier"'
Autor:
Andrew T. Pudzianowski, William A. Schumacher, Christine Huang, Karen S. Hartl, Philip D. Stein, Atsu Apedo, Jing Zhang, S. M. Seiler, Kevin Kish, Yan Shi, Herbert E. Klei, Ming Chang, Nyeemah Grazier, Joseph Yanchunas, Karnail S. Atwal, Doree F. Sitkoff, Eddie C.-K. Liu, Sonia Youssef, Thomas E. Steinbacher, Lorell Discenza
Publikováno v:
Journal of medicinal chemistry. 51(23)
An indole-based P1 moiety was incorporated into a previously established factor Xa inhibitor series. The indole group was designed to hydrogen-bond with the carbonyl of Gly218, while its 3-methyl or 3-chloro substituent was intended to interact with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f48bd1c3c24612b3ae2e2ed3d4cc89
https://pubmed.ncbi.nlm.nih.gov/18998662
https://pubmed.ncbi.nlm.nih.gov/18998662
Autor:
Karnail S. Atwal, Michael Galella, Jack Z. Gougoutas, Philip D. Stein, Sarah C. Traeger, Yan Shi, Jing Zhang, Mary F. Malley, Nyeemah Grazier, Sharon P. Callahan
Publikováno v:
The Journal of organic chemistry. 69(1)
N,N'-Disubstituted ketene aminals are bioisosteres of thioureas and are useful building blocks in many synthetic operations. A convenient one-pot synthesis of N,N'-disubstituted ketene aminals from activated methylene compounds and isothiocyanates is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f711459f147517a66008c8d3852ed4af
https://pubmed.ncbi.nlm.nih.gov/14703396
https://pubmed.ncbi.nlm.nih.gov/14703396
Autor:
Sundeep Dugar, Nyeemah Grazier, Brian J. Gavin, Jack Z. Gougoutas, Mark S. Kirby, Karnail S. Atwal, Kenneth J. Yost, Saleem Ahmad, John D. Dimarco, Lidia M. Doweyko, Bang-Chi Chen, Khehyong Ngu, Charles R. Dorso, Randy Serafino, Shung C. Wu, Alice Y. Chen, Shih-Jung Lan
Publikováno v:
Journal of medicinal chemistry. 44(20)
A novel series of arylcyclopropanecarboxyl guanidines was synthesized and evaluated for activity against the sodium hydrogen exchanger isoform-1 (NHE-1). In biological assays conducted in an AP1 cell line expressing the human NHE-1 isoform, the start
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b859aad05f72c20bac3205c59eda440b
https://pubmed.ncbi.nlm.nih.gov/11563929
https://pubmed.ncbi.nlm.nih.gov/11563929
Autor:
Yan Shi, Jing Shang, Nyeemah Grazier, Stefan, Stein, Philip D., Atwal, Karnail S., Traeger, Sarah C., Callahan, Sharon P., Malley, Mary F., Galella, Michael A., Gougoutas, Jack Z.
Publikováno v:
Journal of Organic Chemistry; 1/9/2004, Vol. 69 Issue 1, p188-191, 4p, 3 Diagrams, 1 Chart