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pro vyhledávání: '"Nuwan P. N. Acharige"'
Autor:
Sonali Bahl, Hongbo Ling, Nuwan P. N. Acharige, Irene Santos-Barriopedro, Mary Kay H. Pflum, Edward Seto
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-17 (2021)
Abstract HDAC1 is the prototypical human histone deacetylase (HDAC) enzyme responsible for catalyzing the removal of acetyl group from lysine residues on many substrate proteins. By deacetylating histones and non-histone proteins, HDAC1 has a profoun
Externí odkaz:
https://doaj.org/article/3bc10b248f614d199456b5bb1c309538
Autor:
Nuwan P. N. Acharige, Mary Kay H. Pflum, Hongbo Ling, Edward Seto, Irene Santos-Barriopedro, Sonali Bahl
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 5, Pp 1-17 (2021)
Cell Death and Disease, Vol 12, Iss 5, Pp 1-17 (2021)
HDAC1 is the prototypical human histone deacetylase (HDAC) enzyme responsible for catalyzing the removal of acetyl group from lysine residues on many substrate proteins. By deacetylating histones and non-histone proteins, HDAC1 has a profound effect
Publikováno v:
Chembiochem
Kinases and phosphatases are major players in a variety of cellular events, including cell signaling. Aberrant activity or mutations in kinases and phosphatases can lead to diseases such as cancer, diabetes, and Alzheimer's. Compared to kinases, phos
Publikováno v:
Molecular Omics. 14:121-133
Phosphorylation is a key post-translational modification in cell signaling, which is regulated by the equilibrium activities of kinases and phosphatases. The biological significance of many phosphorylation events remains poorly characterized due to t