Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nury L. Yim"'
Autor:
Marcel R.M. van den Brink, Derek Sant'Angelo, Martin G. Sauer, Michel Sadelain, Chen Liu, George F. Murphy, Cecilia Lezcano, Alan M. Hanash, Olaf Penack, Robert R. Jenq, Jennifer J. Tsai, Il-Kang Na, Hae Lee, Natalie V. Singer, Mallory L. West, Lauren F. Young, Uttam K. Rao, Nury L. Yim, Yildirim Dogan, Amanda M. Holland, Arnab Ghosh
Supplementary S1: PLZF expression affects CD4+ driven alloreactivity. Supplementary S2: PLZF-TG T cells undergo allo-activation that is similar to donor B6-WT T cells. Supplementary S3: Fewer deaths from GVHD are seen in BMT recipients of PLZF-TG T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810c8eb6280b2a8a46b785a10ae9e89f
https://doi.org/10.1158/0008-5472.22394780.v1
https://doi.org/10.1158/0008-5472.22394780.v1
Autor:
Madeleine Z. Wong, Vivian Bradaschia-Correa, Shane S. Neibart, Sooyeon Lee, Anne M Josephson, Manasa Kadiyala, Hannah P. Litwa, Karan S. Patel, Nury L. Yim, Kevin Leclerc, Philipp Leucht, Matthew M. Mizrahi, Kenneth A. Egol, Austin J. Ramme, Emma Muinos Lopez
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6995-7004
Aging is associated with impaired tissue regeneration. Stem cell number and function have been identified as potential culprits. We first demonstrate a direct correlation between stem cell number and time to bone fracture union in a human patient coh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9673043d4384814ea637f315563019f9
https://doi.org/10.1073/pnas.1810692116
https://doi.org/10.1073/pnas.1810692116
Publikováno v:
Biomaterials. 196:46-50
Advances in the understanding of the complexities of the Wnt signaling pathway during development and tissue homeostasis have made the Wnt pathway one of the prime candidates for translational applications during tissue regeneration. Wnts are key com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32da8faefa07af60b22ee1ae9f4a5bec
https://doi.org/10.1016/j.biomaterials.2018.03.029
https://doi.org/10.1016/j.biomaterials.2018.03.029
Autor:
Anne M Josephson, Matthew M. Mizrahi, Thomas R. Coughlin, Shane S. Neibart, Sooyeon Lee, Nury L. Yim, Dalibel Bravo, Madeleine Z. Wong, Vivian Bradaschia-Correa, Jason C. Huo, Philipp Leucht
Publikováno v:
Bone. 112:97-106
Introduction Aminocaproic acid is approved as an anti-fibrinolytic for use in joint replacement and spinal fusion surgeries to limit perioperative blood loss. Previous animal studies have demonstrated a pro-osteogenic effect of aminocaproic acid in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e64a7af444630a98b92129b6b23f7f
https://doi.org/10.1016/j.bone.2018.04.016
https://doi.org/10.1016/j.bone.2018.04.016
Autor:
Ruchi Tejwani, Danielle H. Markus, Philipp Leucht, Kevin Leclerc, Madeleine Z. Wong, Lindsey H. Remark, Hannah P. Litwa, Vivian Bradaschia-Correa, Sooyeon Lee, Daniel B Buchalter, Rivka C. Ihejirika, Nury L. Yim, Anne M Josephson
Publikováno v:
J Bone Miner Res
Selective serotonin reuptake inhibitors (SSRIs) are one of the most commonly prescribed antidepressants worldwide and recent data show significant impairment of fracture healing after treatment with the SSRI fluoxetine in mice. Here, we provide evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335b77be978b1dbdd2879a639b9f575f
https://pubmed.ncbi.nlm.nih.gov/31881108
https://pubmed.ncbi.nlm.nih.gov/31881108
Autor:
Salma Youssef, Chen Liu, Marcel R.M. van den Brink, Odette M. Smith, Amanda M. Holland, Alan M. Hanash, Yusuke Shono, Jarrod A Dudakov, Kimon V. Argyropoulos, Fabiana M Kreines, Sophie Lieberman, George F. Murphy, Cecilia Lezcano, Robert R. Jenq, Uttam K. Rao, Il-Kang Na, Jennifer Tsai, Nury L. Yim, Lauren F. Young, Enrico Velardi, Ya-Yuan Fu, Amina Lazrak
Nuclear factor erythroid-derived 2-like 2 (Nrf2) is a ubiquitously expressed transcription factor that is well known for its role in regulating the cellular redox pathway. Although there is mounting evidence suggesting a critical role for Nrf2 in hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4c19adabc2348e72c4d8d66a65ac83
https://europepmc.org/articles/PMC6307985/
https://europepmc.org/articles/PMC6307985/
Autor:
George F. Murphy, Lauren F. Young, Michel Sadelain, Yildirim Dogan, Maxim A. Moroz, Enrico Velardi, Chen Liu, Nury L. Yim, Jennifer Tsai, Uttam K. Rao, Odette M. Smith, Robert R. Jenq, Daniel Tannenbaum, Alan M. Hanash, M. Lia Palomba, Vladimir Ponomarev, Cecilia Lezcano, Arnab Ghosh, Olaf Penack, Martin Sauer, Kelly Piersanti, Marcel R.M. van den Brink, Amanda M. Holland, Durva Masih
Publikováno v:
Journal of Clinical Investigation. 123:2654-2662
Current strategies to suppress graft-versus-host disease (GVHD) also compromise graft-versus-tumor (GVT) responses. Furthermore, most experimental strategies to separate GVHD and GVT responses merely spare GVT function without actually enhancing it.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bd5eeb15332349025aada322b0c29e8
https://doi.org/10.1172/jci66301
https://doi.org/10.1172/jci66301
Autor:
Marcel R.M. van den Brink, Arnab Ghosh, Jennifer Tsai, Ronald G. Blasberg, John C. Markley, Alexander D. Klose, Nury L. Yim, Bradley J. Beattie, Elmer Santos, Inna Serganova, Il-Kang Na, Renier J. Brentjens, Amanda M. Holland, Matthias Stephan, Uttam K. Rao, Michel Sadelain
Publikováno v:
Blood. 116:e18-e25
We have developed a dual bioluminescent reporter system allowing noninvasive, concomitant imaging of T-cell trafficking, expansion, and activation of nuclear factor of activated T cells (NFAT) in vivo. NFAT activation plays an important role in T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b12032ad31b768a3c541484d0b2866a
https://doi.org/10.1182/blood-2009-12-259432
https://doi.org/10.1182/blood-2009-12-259432
Autor:
Christine Volk, Christopher G. King, Onder Alpdogan, Gabrielle L. Goldberg, Odette M. Smith, Sydney X. Lu, Miguel-Angel Perales, Robert R. Jenq, Marcel R.M. van den Brink, Nury L. Yim, David Suh, Lucy W. Kappel, Amanda M. Holland, Uttam K. Rao, Adi Diab, Jedd D. Wolchok, Alan N. Houghton, Il-Kang Na, Olaf Penack, Johannes L. Zakrzewski
Publikováno v:
Blood. 113:1574-1580
Keratinocyte growth factor (KGF), which is given exogenously to allogeneic bone marrow transplantation (allo-BMT) recipients, supports thymic epithelial cells and increases thymic output of naive T cells. Here, we demonstrate that this improved T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d575bcf8ca3ea3ba1da0c1e7cf7b0dce
https://doi.org/10.1182/blood-2008-05-155697
https://doi.org/10.1182/blood-2008-05-155697
Autor:
Jennifer Tsai, Michel Sadelain, Marcel R.M. van den Brink, Hae Lee, Amanda M. Holland, Nury L. Yim, George F. Murphy, Chen Liu, Derek B. Sant'Angelo, Cecilia Lezcano, Alan M. Hanash, Uttam K. Rao, Il-Kang Na, Martin Sauer, Lauren F. Young, Mallory L. West, Natalie V. Singer, Robert R. Jenq, Arnab Ghosh, Olaf Penack, Yildirim Dogan
Publikováno v:
Cancer research. 73(15)
Efforts to limit GVHD mediated by alloreactive donor T cells after allogeneic bone marrow transplantation are limited by a concomitant decrease in graft-versus-tumor (GVT) activity and increased possibilities of tumor relapse. Using a novel approach,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4a2b5467c18a8fd9491457e48a9d01
https://pubmed.ncbi.nlm.nih.gov/23733752
https://pubmed.ncbi.nlm.nih.gov/23733752