Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Nuruddeen D Lewis"'
Autor:
Nuruddeen D Lewis, Lori A Patnaude, Josephine Pelletier, Donald J Souza, Susan M Lukas, F James King, Jonathan D Hill, Dimitria E Stefanopoulos, Kelli Ryan, Sudha Desai, Donna Skow, Stefan G Kauschke, Andre Broermann, Daniel Kuzmich, Christian Harcken, Eugene R Hickey, Louise K Modis
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100883 (2014)
GPBAR1 is a G protein-coupled receptor that is activated by certain bile acids and plays an important role in the regulation of bile acid synthesis, lipid metabolism, and energy homeostasis. Recent evidence suggests that GPBAR1 may also have importan
Externí odkaz:
https://doaj.org/article/26efe3ddb1914034965ffa796c1b72fb
Autor:
Nuruddeen D Lewis, Akalushi Muthukumarana, Steven E Fogal, Laura Corradini, Dimitria E Stefanopoulos, Prathima Adusumalli, Josephine Pelletier, Mark Panzenbeck, Karen Berg, Melissa Canfield, Brian N Cook, Hossein Razavi, Daniel Kuzmich, Shawn Anderson, Devan Allard, Paul Harrison, Christine Grimaldi, Donald Souza, Christian Harcken, Ryan M Fryer, Louise K Modis, Maryanne L Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105883 (2014)
Inflammation is associated with immune cells infiltrating into the inflammatory site and pain. CC chemokine receptor 1 (CCR1) mediates trafficking of leukocytes to sites of inflammation. However, the contribution of CCR1 to pain is incompletely under
Externí odkaz:
https://doaj.org/article/81669bfd30b848adb34caf77ca3b6e5b
Autor:
Daniel P Barry, Mohammad Asim, Brooks P Scull, M Blanca Piazuelo, Thibaut de Sablet, Nuruddeen D Lewis, Lori A Coburn, Kshipra Singh, Lesley G Ellies, Alain P Gobert, Rupesh Chaturvedi, Keith T Wilson
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29046 (2011)
Once acquired, Helicobacter pylori infection is lifelong due to an inadequate innate and adaptive immune response. Our previous studies indicate that interactions among the various pathways of arginine metabolism in the host are critical determinants
Externí odkaz:
https://doaj.org/article/09ba87fccc7840d89038169ee39687b0
Autor:
Sriram Sathyanarayanan, Douglas E. Williams, Kyriakos D. Economides, Scott Estes, Leonid Gaidukov, Michael Doherty, Jorge Sanchez-Salazar, Christine McCoy, Andrew Grube, Adam Boutin, Bryan Choi, Su Chul Jang, Kevin Dooley, Ke Xu, Tong Zi, Gauri Mahimkar, Sonya Haupt, Katherine Kirwin, Chang Ling Sia, Nuruddeen D. Lewis
Reagents and antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0cc52ff5f90d222f6c91fd94d9fb5d
https://doi.org/10.1158/1535-7163.22520857.v1
https://doi.org/10.1158/1535-7163.22520857.v1
Autor:
Sriram Sathyanarayanan, Douglas E. Williams, Kyriakos D. Economides, Scott Estes, Leonid Gaidukov, Michael Doherty, Jorge Sanchez-Salazar, Christine McCoy, Andrew Grube, Adam Boutin, Bryan Choi, Su Chul Jang, Kevin Dooley, Ke Xu, Tong Zi, Gauri Mahimkar, Sonya Haupt, Katherine Kirwin, Chang Ling Sia, Nuruddeen D. Lewis
The promise of IL12 as a cancer treatment has yet to be fulfilled with multiple tested approaches being limited by unwanted systemic exposure and unpredictable pharmacology. To address these limitations, we generated exoIL12, a novel, engineered exos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48f064854755ca4ed6549b6b5758945
https://doi.org/10.1158/1535-7163.c.6542815.v1
https://doi.org/10.1158/1535-7163.c.6542815.v1
Autor:
Sriram Sathyanarayanan, Douglas E. Williams, Kyriakos D. Economides, Scott Estes, Leonid Gaidukov, Michael Doherty, Jorge Sanchez-Salazar, Christine McCoy, Andrew Grube, Adam Boutin, Bryan Choi, Su Chul Jang, Kevin Dooley, Ke Xu, Tong Zi, Gauri Mahimkar, Sonya Haupt, Katherine Kirwin, Chang Ling Sia, Nuruddeen D. Lewis
Mean Cytokine Values in Cynomolgus Plasma After Subcutaneous Dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72abef236439adc462be2e495a07859
https://doi.org/10.1158/1535-7163.22520860.v1
https://doi.org/10.1158/1535-7163.22520860.v1
Autor:
Sriram Sathyanarayanan, Douglas E. Williams, Kyriakos D. Economides, Scott Estes, Leonid Gaidukov, Michael Doherty, Jorge Sanchez-Salazar, Christine McCoy, Andrew Grube, Adam Boutin, Bryan Choi, Su Chul Jang, Kevin Dooley, Ke Xu, Tong Zi, Gauri Mahimkar, Sonya Haupt, Katherine Kirwin, Chang Ling Sia, Nuruddeen D. Lewis
Fold-change Cytokine Values in Cynomolgus Plasma After Subcutaneous Dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565f93cee3c4ea09b46e8867aafda435
https://doi.org/10.1158/1535-7163.22520869.v1
https://doi.org/10.1158/1535-7163.22520869.v1
Autor:
Sriram Sathyanarayanan, Douglas E. Williams, Kyriakos D. Economides, Scott Estes, Leonid Gaidukov, Michael Doherty, Jorge Sanchez-Salazar, Christine McCoy, Andrew Grube, Adam Boutin, Bryan Choi, Su Chul Jang, Kevin Dooley, Ke Xu, Tong Zi, Gauri Mahimkar, Sonya Haupt, Katherine Kirwin, Chang Ling Sia, Nuruddeen D. Lewis
Figures S1 through S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c5b51e812ca6bddaccbe1b538f459a
https://doi.org/10.1158/1535-7163.22520863
https://doi.org/10.1158/1535-7163.22520863
Autor:
Sriram Sathyanarayanan, Douglas E. Williams, Kyriakos D. Economides, Scott Estes, Leonid Gaidukov, Michael Doherty, Jorge Sanchez-Salazar, Christine McCoy, Andrew Grube, Adam Boutin, Bryan Choi, Su Chul Jang, Kevin Dooley, Ke Xu, Tong Zi, Gauri Mahimkar, Sonya Haupt, Katherine Kirwin, Chang Ling Sia, Nuruddeen D. Lewis
20201229pdtedSupplementaryFigures.pdf from Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187f061226a25f50c15b215a72a23107
https://doi.org/10.1158/1535-7163.22520872.v1
https://doi.org/10.1158/1535-7163.22520872.v1
Autor:
Sriram Sathyanarayanan, Dalia Burzyn, Su Chul Jang, Sonya Haupt, Mcconnell Russell E, Scott Estes, Charan Leng, Ke Xu, James E. Thornton, Raymond J. Moniz, Kyriakos D. Economides, Nikki L. Ross, Youniss Madeleine, Rane A. Harrison, Olga Burenkova, Chang Ling Sia, Kevin Dooley, Martin Shelly, Jonathan D. Finn, Jorge Sanchez-Salazar, Kulman John D, Bryan D. Choi, Damian Houde, Christine McCoy, Nuruddeen D. Lewis, Katherine Kirwin, Leonid Gaidukov, Williams Douglas E
Publikováno v:
Mol Ther
Extracellular vesicles (EVs) are an important intercellular communication system facilitating the transfer of macromolecules between cells. Delivery of exogenous cargo tethered to the EV surface or packaged inside the lumen are key strategies for gen