NTHL1 is a recessive cancer susceptibility gene.

Autor: Nurmi AK; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Pelttari LM; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Kiiski JI; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Khan S; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Nurmikolu M; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Suvanto M; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Aho N; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland., Tasmuth T; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kalso E; Department of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Schleutker J; Institute of Biomedicine, University of Turku, and FICAN West Cancer Centre, and Department of Genomics, Laboratory Division, Turku University Hospital, Turku, Finland., Kallioniemi A; Tays Cancer Center, Tampere University Hospital, and BioMediTech Institute and Faculty of Medicine and Health Technology, Tampere University, and Fimlab Laboratories, Tampere, Finland., Heikkilä P; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Aittomäki K; Department of Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Blomqvist C; Department of Oncology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Biomedicum Helsinki, P.O. Box 700, 00290, Helsinki, Finland. heli.nevanlinna@hus.fi.

Publikováno v: Scientific reports [Sci Rep] 2023 Nov 30; Vol. 13 (1), pp. 21127. Date of Electronic Publication: 2023 Nov 30.

Effects of single doses of quinapril and atenolol on autonomic nervous function and exercise capacity in healthy volunteers

Autor: Ilkka Pörsti, Vesa Manninen, K. Koskenvuo, Timo Metsä-Ketelä, L. A. Laitinen, Heikki Vapaatalo, Nurmi Ak, Pertti Arvola, Säynävälammi P

Publikováno v: European Journal of Clinical Pharmacology. 38:541-546

The effects of single oral doses of the angiotensin converting enzyme (ACE) inhibitor quinapril (CI-906) 40 mg and the cardioselective beta-adrenoceptor blocker atenolol 100 mg on sympathetic and parasympathetic function and on exercise capacity have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba51aa87c25fd50751ef29b1dcc9093
https://doi.org/10.1007/bf00278578

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Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol

Autor: Nurmi Ak, Pauli Ylitalo, Erkki Seppälä, M.-L. Pyykönen, Timo Pitkäjärvi, Heikki Vapaatalo

Publikováno v: Clinical pharmacology and therapeutics. 38(4)

The interaction of inhibition of prostaglandin (PG) synthesis by indomethacin (75 mg/day) with the antihypertensive effect of atenolol (50 mg b.i.d.) was studied in 11 untreated otherwise healthy men 35 to 45 years old with essential hypertension. At

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35da91abdfb969ea9edcf73755d94578
https://pubmed.ncbi.nlm.nih.gov/3899459

Effects of indomethacin on hormonal and blood pressure responses to captopril in spontaneously hypertensive rats

Autor: Pertti Arvola, Nurmi Ak, Erkki Seppälä, Kari Kuismanen, Vesa Manninen, Heikki Vapaatalo, Säynävälammi P

Publikováno v: Pharmacologytoxicology. 61(3)

The possible role of vasodilatory prostanoids in the antihypertensive action of captopril was investigated in spontaneously hypertensive rats (SHR). Captopril (100 mg/kg/day for 5 days) decreased systolic blood pressure and increased water consumptio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45965a1289c1fd05fe3e164519be089
https://pubmed.ncbi.nlm.nih.gov/3317383