Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nurjahan Mehzabeen"'
Autor:
Mark Hutchinson, Jeffrey A. Ruffolo, Nantaporn Haskins, Michael Iannotti, Giuliana Vozza, Tony Pham, Nurjahan Mehzabeen, Harini Shandilya, Keith Rickert, Rebecca Croasdale-Wood, Melissa Damschroder, Ying Fu, Andrew Dippel, Jeffrey J. Gray, Gilad Kaplan
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Over the past two decades, therapeutic antibodies have emerged as a rapidly expanding domain within the field of biologics. In silico tools that can streamline the process of antibody discovery and optimization are critical to support a pipeline that
Externí odkaz:
https://doaj.org/article/fd2f8ba9525448dbbf68ca2c03eef55e
Autor:
Wayne Harshbarger, Sai Tian, Newton Wahome, Ankita Balsaraf, Deep Bhattacharya, Desheng Jiang, Ratnesh Pandey, Kunal Tungare, Kristian Friedrich, Nurjahan Mehzabeen, Marco Biancucci, Diana Chinchilla-Olszar, Corey P Mallett, Ying Huang, Zihao Wang, Matthew James Bottomley, Enrico Malito, Sumana Chandramouli
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008943 (2020)
Respiratory syncytial virus (RSV) is a global public health burden for which no licensed vaccine exists. To aid vaccine development via increased understanding of the protective antibody response to RSV prefusion glycoprotein F (PreF), we performed s
Externí odkaz:
https://doaj.org/article/98f5af6f2dbe4087aa5a737f65ccd637
Autor:
Hao Yu, Patricia Dranchak, Zhiru Li, Ryan MacArthur, Matthew S. Munson, Nurjahan Mehzabeen, Nathan J. Baird, Kevin P. Battalie, David Ross, Scott Lovell, Clotilde K. S. Carlow, Hiroaki Suga, James Inglese
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
River blindness, a disease affecting millions throughout the tropics, is caused by parasitic worms. Here, Yuet al. report the discovery and structural characterization of potent macrocyclic peptide inhibitors of iPGM, a nematode-specific phosphoglyce
Externí odkaz:
https://doaj.org/article/39345025d3334fe096b7ce4373349fee
Autor:
David R. Benson, Scott Lovell, Nurjahan Mehzabeen, Nadezhda Galeva, Anne Cooper, Philip Gao, Kevin P. Battaile, Hao Zhu
Publikováno v:
Acta Crystallographica Section D Structural Biology. 75:628-638
Ncb5or (NADH-cytochrome b 5 oxidoreductase), a cytosolic ferric reductase implicated in diabetes and neurological diseases, comprises three distinct domains, cytochrome b 5 (b 5) and cytochrome b 5 reductase (b 5R) domains separated by a CHORD–Sgt1
Autor:
Harry Scott, Wei Huang, Kiran Andra, Sireesha Mamillapalli, Srinivas Gonti, Alexander Day, Kaiming Zhang, Nurjahan Mehzabeen, Kevin P. Battaile, Anjali Raju, Scott Lovell, James G. Bann, Derek J. Taylor
Publikováno v:
Journal of Molecular Biology. 434:167548
The tripartite protein complex produced by anthrax bacteria (Bacillus anthracis) is a member of the AB family of β-barrel pore-forming toxins. The protective antigen (PA) component forms an oligomeric prepore that assembles on the host cell surface
Autor:
Nurjahan Mehzabeen, Matthew J. Bottomley, Sai Tian, Wayne Harshbarger, Diana Chinchilla-Olszar, Sumana Chandramouli, Zihao Wang, Marco Biancucci, Deep S. Bhattacharya, Kristian Friedrich, Ying Huang, Newton Muchugu Wahome, Desheng Jiang, Corey P. Mallett, Enrico Malito, Ratnesh Pandey, Ankita Balsaraf, Kunal Tungare
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 11, p e1008943 (2020)
PLoS Pathogens, Vol 16, Iss 11, p e1008943 (2020)
Respiratory syncytial virus (RSV) is a global public health burden for which no licensed vaccine exists. To aid vaccine development via increased understanding of the protective antibody response to RSV prefusion glycoprotein F (PreF), we performed s
Autor:
Sebastian J. Karuppan, Michal Hammel, David R. Hall, Salvatore L. Stella, Sheila Harroch, Véronique Dubreuil, Nurjahan Mehzabeen, Roman M. Nikolaienko, Samuel Bouyain, Rana Zalmai
Publikováno v:
The Journal of biological chemistry. 291(41)
Protein-tyrosine phosphatase receptor type G (RPTPγ/PTPRG) interacts in vitro with contactin-3–6 (CNTN3–6), a group of glycophosphatidylinositol-anchored cell adhesion molecules involved in the wiring of the nervous system. In addition to PTPRG,
Autor:
AnushkaC. Galasiti Kankanamalage, Yunjeong Kim, Pathum M. Weerawarna, Roxanne Adeline Z. Uy, Vishnu C. Damalanka, SivakoteswaraRao Mandadapu, Kevin R. Alliston, Nurjahan Mehzabeen, Kevin P. Battaile, Scott Lovell, Kyeong-Ok Chang, William C. Groutas
Publikováno v:
Journal of Medicinal Chemistry; Apr2015, Vol. 58 Issue 7, p3144-3155, 12p