Synthesis and in vitro evaluation of new 5-substituted 6-nitroimidazooxazoles as antikinetoplastid agents

Autor: Nadine Azas, Roberto Docampo, Nuria Waddington Negrao, Fanny Mathias, Anita Cohen, Patrice Vanelle, Maxime D. Crozet, Youssef Kabri

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 191, pp.112146. ⟨10.1016/j.ejmech.2020.112146⟩
European Journal of Medicinal Chemistry, 2020, 191, pp.112146. ⟨10.1016/j.ejmech.2020.112146⟩

International audience; In continuation of our pharmacomodulation work on the nitroimidazooxazole series, we report the synthesis of new 5-substituted 6-nitroimidazooxazole derivatives. Our aim was to evaluate how func-tionalization of the 5-position

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32269c6b4ea93d709d56146020dc6e71
https://hal-amu.archives-ouvertes.fr/hal-02504497

Prevention of palatable diet-induced hyperphagia in rats by central injection of a VEGFR kinase inhibitor

Autor: Anastasia M. Bobilev, Ping Shen, Haini N. Cai, Nuria Waddington Negrao, Audrey Branch

Publikováno v: Behavioural Brain Research. 278:506-513

Our previous studies have demonstrated a critical role of a VEGFR-like signaling pathway in hunger-driven overeating of sugar-rich food in Drosophila larvae. In the current study, we investigate whether the VEGFR signaling mechanism plays a similar r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c466f7c0443a7332dafde04e856ddcde
https://doi.org/10.1016/j.bbr.2014.10.004