Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Nuria Tubau-Juni"'
Autor:
Nuria Tubau-Juni, Josep Bassaganya-Riera, Andrew J. Leber, Sameeksha S. Alva, Ryan Baker, Raquel Hontecillas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated diarrhea, and its clinical symptoms can span from asymptomatic colonization to pseudomembranous colitis and even death. The current standard of care for C
Externí odkaz:
https://doaj.org/article/c6144bacee3149aaa47fc7de462e72ae
Autor:
Ryan Baker, Raquel Hontecillas, Nuria Tubau-Juni, Andrew J. Leber, Shiv Kale, Josep Bassaganya-Riera
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract We built a computational model of complex mechanisms at the intersection of immunity and metabolism that regulate CD4+ T cell effector and regulatory functions by using coupled ordinary differential equations. The model provides an improved
Externí odkaz:
https://doaj.org/article/9754d031717c4f2591084d2eeacaf939
Autor:
Nuria Tubau-Juni, Raquel Hontecillas, Andrew Leber, Panita Maturavongsadit, Jyoti Chauhan, Josep Bassaganya-Riera
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Psoriasis (PsO) is a complex immune-mediated disease that afflicts 100 million people. Omilancor is a locally-acting, small molecule that selectively activates the Lanthionine Synthetase C-like 2 (LANCL2) pathway, resulting in immunoregulato
Externí odkaz:
https://doaj.org/article/c1c4b1022cbb4c39b88270c685e5b4e6
Autor:
Bridget Kastelberg, Tariq Ayubi, Nuria Tubau-Juni, Andrew Leber, Raquel Hontecillas, Josep Bassaganya-Riera, Shiv D. Kale
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The Nlr family member X1 (Nlrx1) is an immuno-metabolic hub involved in mediating effective responses to virus, bacteria, fungi, cancer, and auto-immune diseases. We have previously shown that Nlrx1 is a critical regulator of immune signaling and mor
Externí odkaz:
https://doaj.org/article/e39ee8d27ab84fe38efeac95a51892aa
Autor:
Bridget Kastelberg, Nuria Tubau-Juni, Tariq Ayubi, Austin Leung, Andrew Leber, Raquel Hontecillas, Josep Bassaganya-Riera, Shiv D Kale
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008854 (2020)
Aspergillus fumigatus is an opportunistic fungal pathogen of immunocompromised patient populations. Mortality is thought to be context-specific and occurs via both enhanced fungal growth and immunopathogenesis. NLRX1 is a negative regulator of immune
Externí odkaz:
https://doaj.org/article/77f386d51f08479989c5680a9aa91e55
Autor:
Shiv D. Kale, Tariq Ayubi, Dawoon Chung, Nuria Tubau-Juni, Andrew Leber, Ha X. Dang, Saikumar Karyala, Raquel Hontecillas, Christopher B. Lawrence, Robert A. Cramer, Josep Bassaganya-Riera
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-25 (2017)
Abstract Incidences of invasive pulmonary aspergillosis, an infection caused predominantly by Aspergillus fumigatus, have increased due to the growing number of immunocompromised individuals. While A. fumigatus is reliant upon deficiencies in the hos
Externí odkaz:
https://doaj.org/article/3e1eb754a5404bed9918e73fc0cf64c9
Publikováno v:
Frontiers in Nutrition, Vol 5 (2018)
Externí odkaz:
https://doaj.org/article/b2024db72808420980c63105a1887a27
Autor:
Andrew Leber, Raquel Hontecillas, Nuria Tubau-Juni, Victoria Zoccoli-Rodriguez, Vida Abedi, Josep Bassaganya-Riera
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Interactions among the gut microbiome, dysregulated immune responses, and genetic factors contribute to the pathogenesis of inflammatory bowel disease (IBD). Nlrx1−/− mice have exacerbated disease severity, colonic lesions, and increased inflamma
Externí odkaz:
https://doaj.org/article/faa213f48cec4f61abfd81bcdce6f874
Autor:
Elena Zocchi, Raquel Hontecillas, Andrew Leber, Alexandra Einerhand, Adria Carbo, Santina Bruzzone, Nuria Tubau-Juni, Noah Philipson, Victoria Zoccoli-Rodriguez, Laura Sturla, Josep Bassaganya-Riera
Publikováno v:
Frontiers in Nutrition, Vol 4 (2017)
Abscisic acid is naturally present in fruits and vegetables, and it plays an important role in managing glucose homeostasis in humans. According to the latest U.S. dietary survey, about 92% of the population might have a deficient intake of ABA due t
Externí odkaz:
https://doaj.org/article/de033391bab54af1869d63ef71304511
Autor:
Andrew Leber, Josep Bassaganya-Riera, Nuria Tubau-Juni, Victoria Zoccoli-Rodriguez, Monica Viladomiu, Vida Abedi, Pinyi Lu, Raquel Hontecillas
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167440 (2016)
Immune responses to Helicobacter pylori are orchestrated through complex balances of host-bacterial interactions, including inflammatory and regulatory immune responses across scales that can lead to the development of the gastric disease or the prom
Externí odkaz:
https://doaj.org/article/d130a2449e964f899d955596b805fcf9