Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nuria Ruiz-Reig"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Neuronal apoptosis is a mechanism used to clear the cells of oxidative stress or DNA damage and refine the final number of neurons for a functional neuronal circuit. The tumor suppressor protein p53 is a key regulator of the cell cycle and serves as
Externí odkaz:
https://doaj.org/article/7e4a9404916b44d6bfb9421150449e9a
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 375-379 (2024)
Microtubules play a central role in cytoskeletal changes during neuronal development and maintenance. Microtubule dynamics is essential to polarity and shape transitions underlying neural cell division, differentiation, motility, and maturation. Kine
Externí odkaz:
https://doaj.org/article/65944d79260f491ca2290b47906b8117
Autor:
Malalaniaina Rakotobe, Niels Fjerdingstad, Nuria Ruiz-Reig, Thomas Lamonerie, Fabien D'Autréaux
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106392- (2024)
Having experienced stress during sensitive periods of brain development strongly influences how individuals cope with later stress. Some are prone to develop anxiety or depression, while others appear resilient. The as-yet-unknown mechanisms underlyi
Externí odkaz:
https://doaj.org/article/ec026ddf2eb94e10b3dff37d170f9278
Autor:
Georges Chehade, Nady El Hajj, Mohamed Aittaleb, Maisa I. Alkailani, Yosra Bejaoui, Asma Mahdi, Arwa A. H. Aldaalis, Michael Verbiest, Julie Lelotte, Nuria Ruiz-Reig, Irene Durá, Christian Raftopoulos, Nicolas Tajeddine, Fadel Tissir
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundGlioblastoma is one of the most aggressive primary brain tumors, with a poor outcome despite multimodal treatment. Methylation of the MGMT promoter, which predicts the response to temozolomide, is a well-established prognostic marker for gl
Externí odkaz:
https://doaj.org/article/1369f93b831e4ee098f1f9224cf0cca6
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
Malformation of cortical development (MCD) is a family of neurodevelopmental disorders, which usually manifest with intellectual disability and early-life epileptic seizures. Mutations in genes encoding microtubules (MT) and MT-associated proteins ar
Externí odkaz:
https://doaj.org/article/a03b1909262a448b9594064936d18ae7
Autor:
Eva On-Chai Lau, Devid Damiani, Georges Chehade, Nuria Ruiz-Reig, Rana Saade, Yves Jossin, Mohamed Aittaleb, Olivier Schakman, Nicolas Tajeddine, Philippe Gailly, Fadel Tissir
Publikováno v:
eLife, Vol 10 (2021)
Diaphanous (DIAPH) three (DIAPH3) is a member of the formin proteins that have the capacity to nucleate and elongate actin filaments and, therefore, to remodel the cytoskeleton. DIAPH3 is essential for cytokinesis as its dysfunction impairs the contr
Externí odkaz:
https://doaj.org/article/de76d6fb42264b29a8ccdd3a42ddfd9d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Cell polarity refers to the asymmetric distribution of signaling molecules, cellular organelles, and cytoskeleton in a cell. Neural progenitors and neurons are highly polarized cells in which the cell membrane and cytoplasmic components are compartme
Externí odkaz:
https://doaj.org/article/df0990baa61a4222b9087e8e659cbac6
Autor:
Nuria Ruiz-Reig, Michèle Studer
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The generation and differentiation of an appropriate number of neurons, as well as its distribution in different parts of the brain, is crucial for the proper establishment, maintenance and plasticity of neural circuitries. Newborn neurons travel alo
Externí odkaz:
https://doaj.org/article/8a02a99145f946e8a73a80e06c1a1245
Autor:
Nuria Ruiz-Reig, Georges Chehade, Janne Hakanen, Mohamed Aittaleb, Keimpe Wierda, Joris De Wit, Laurent Nguyen, Philippe Gailly, Fadel Tissir
Publikováno v:
Proceedings of the National academy of sciences of the United States of America, Vol. 119, no.46 (2022)
KIF2A is an atypical kinesin that has the capacity to depolymerize microtubules. Patients carrying mutations in KIF2A suffer from progressive microcephaly and mental disabilities. While the role of this protein is well documented in neuronal migratio
Autor:
Malalaniaina Rakotobe, Niels Fjerdingstad, Nuria Ruiz-Reig, Thomas Lamonerie, Fabien D'Autréaux
Having experienced stress during sensitive periods of brain development strongly impacts how individuals cope with later stress. Many become more prone to develop anxiety or depression, but some appear resilient. The as-yet-unknown mechanisms underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fceb54c47d62b27335c22f2342acba6f
https://doi.org/10.21203/rs.3.rs-823079/v4
https://doi.org/10.21203/rs.3.rs-823079/v4