Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nuria Planell"'
Autor:
Sara Palomino-Echeverria, Estefania Huergo, Asier Ortega-Legarreta, Eva M. Uson Raposo, Ferran Aguilar, Carlos de la Peña-Ramirez, Cristina López-Vicario, Carlo Alessandria, Wim Laleman, Alberto Queiroz Farias, Richard Moreau, Javier Fernandez, Vicente Arroyo, Paolo Caraceni, Vincenzo Lagani, Cristina Sánchez-Garrido, Joan Clària, Jesper Tegner, Jonel Trebicka, Narsis A. Kiani, Nuria Planell, Pierre-Emmanuel Rautou, David Gomez-Cabrero
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Patient heterogeneity poses significant challenges for managing individuals and designing clinical trials, especially in complex diseases. Existing classifications rely on outcome-predicting scores, potentially overlooking crucial
Externí odkaz:
https://doaj.org/article/afc33b047ee34914a86a10e0483c2fdb
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Daniel Mouzo, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Clinical trials have shown that lentiviral-mediated gene therapy can ameliorate bone marrow failure (BMF) in nonconditioned Fanconi anemia (FA) patients resulting from the proliferative advantage of corrected FA hematopoietic stem and progenitor cell
Externí odkaz:
https://doaj.org/article/d53a95898f024aef96171022924acc08
Autor:
Lara Kular, Dennis Klose, Amaya Urdánoz-Casado, Ewoud Ewing, Nuria Planell, David Gomez-Cabrero, Maria Needhamsen, Maja Jagodic
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundMultiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS) characterized by irreversible disability at later progressive stages. A growing body of evidence suggests that disease progressi
Externí odkaz:
https://doaj.org/article/aa9b6d4c84d341598d715e8337737b59
Autor:
Jin Ye, Isabel A. Calvo, Itziar Cenzano, Amaia Vilas, Xabier Martinez-de-Morentin, Miren Lasaga, Diego Alignani, Bruno Paiva, Ana C. Viñado, Patxi San Martin-Uriz, Juan P. Romero, Delia Quilez Agreda, Marta Miñana Barrios, Ignacio Sancho-González, Gabriele Todisco, Luca Malcovati, Nuria Planell, Borja Saez, Jesper N. Tegner, Felipe Prosper, David Gomez-Cabrero
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104225- (2022)
Summary: Understanding the regulation of normal and malignant human hematopoiesis requires comprehensive cell atlas of the hematopoietic stem cell (HSC) regulatory microenvironment. Here, we develop a tailored bioinformatic pipeline to integrate publ
Externí odkaz:
https://doaj.org/article/ccde1bb022e24ec1a1f2e788e69807b2
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Gene-set analysis tools, which make use of curated sets of molecules grouped based on their shared functions, aim to identify which gene-sets are over-represented in the set of features that have been associated with a given trait
Externí odkaz:
https://doaj.org/article/77383f4fa7fd4824b897ff8e8f9b4c4c
Autor:
Nuria Planell, Vincenzo Lagani, Patricia Sebastian-Leon, Frans van der Kloet, Ewoud Ewing, Nestoras Karathanasis, Arantxa Urdangarin, Imanol Arozarena, Maja Jagodic, Ioannis Tsamardinos, Sonia Tarazona, Ana Conesa, Jesper Tegner, David Gomez-Cabrero
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Technologies for profiling samples using different omics platforms have been at the forefront since the human genome project. Large-scale multi-omics data hold the promise of deciphering different regulatory layers. Yet, while there is a myriad of bi
Externí odkaz:
https://doaj.org/article/99f7643058d144149055b509b7075821
Autor:
Marta Larrayoz, Maria J. Garcia-Barchino, Jon Celay, Amaia Etxebeste, Maddalen Jimenez, Cristina Perez, Raquel Ordoñez, Cesar Cobaleda, Cirino Botta, Vicente Fresquet, Sergio Roa, Ibai Goicoechea, Catarina Maia, Miren Lasaga, Marta Chesi, P. Leif Bergsagel, Maria J. Larrayoz, Maria J. Calasanz, Elena Campos-Sanchez, Jorge Martinez-Cano, Carlos Panizo, Paula Rodriguez-Otero, Silvestre Vicent, Giovanna Roncador, Patricia Gonzalez, Satoru Takahashi, Samuel G. Katz, Loren D. Walensky, Shannon M. Ruppert, Elisabeth A. Lasater, Maria Amann, Teresa Lozano, Diana Llopiz, Pablo Sarobe, Juan J. Lasarte, Nuria Planell, David Gomez-Cabrero, Olga Kudryashova, Anna Kurilovich, Maria V. Revuelta, Leandro Cerchietti, Xabier Agirre, Jesus San Miguel, Bruno Paiva, Felipe Prosper, Jose A. Martinez-Climent
The historical lack of preclinical models reflecting the genetic heterogeneity of multiple myeloma (MM) hampers the advance of therapeutic discoveries. To circumvent this limitation, we screened mice engineered to carry eight MM lesions (NF-κB, KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2563a745972cadf6c4af5126546113b9
https://hdl.handle.net/10171/65914
https://hdl.handle.net/10171/65914
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-7 (2020)
BMC Bioinformatics
BMC Bioinformatics
Background Gene-set analysis tools, which make use of curated sets of molecules grouped based on their shared functions, aim to identify which gene-sets are over-represented in the set of features that have been associated with a given trait of inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1583872d24c05f220c2e4c58191551cb
http://link.springer.com/article/10.1186/s12859-020-03784-z
http://link.springer.com/article/10.1186/s12859-020-03784-z
Autor:
Joaquín Cubiella, Mar Rodríguez-Girondo, L De Chiara, Manel Esteller, A. Etxart, Nuria Planell, David Gomez-Cabrero, Sebastian Moran, Francesc Balaguer, Luis Bujanda, Rodrigo Jover, Antoni Castells, María Gallardo-Gómez
BackgroundEarly detection through screening programs has proven to be the most effective strategy to reduce the incidence and mortality of colorectal cancer. The most widely implemented non-invasive screening test is the fecal immunochemical test, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a12a9e2c0aa1e03e6597981a62dc6bb7
https://doi.org/10.1101/2021.11.11.21266182
https://doi.org/10.1101/2021.11.11.21266182
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
SUMMARY PARAGRAPH Fanconi anemia (FA) is a monogenic inherited disease associated with mutations in genes that encode for proteins participating in the FA/BRCA DNA repair pathway. Mutations in FA genes result in chromosomal instability and cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db0bf3349847b11087227da6bf0f549
https://doi.org/10.1101/2021.07.20.21260460
https://doi.org/10.1101/2021.07.20.21260460