Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nuria Martínez Martín"'
Autor:
Marta Iborra-Pernichi, Jonathan Ruiz García, María Velasco de la Esperanza, Belén S. Estrada, Elena R. Bovolenta, Claudia Cifuentes, Cristina Prieto Carro, Tamara González Martínez, José García-Consuegra, María Fernanda Rey-Stolle, Francisco Javier Rupérez, Milagros Guerra Rodriguez, Rafael J. Argüello, Sara Cogliati, Fernando Martín-Belmonte, Nuria Martínez-Martín
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The B cell response in the germinal centre (GC) reaction requires a unique bioenergetic supply. Although mitochondria are remodelled upon antigen-mediated B cell receptor stimulation, mitochondrial function in B cells is still poorly underst
Externí odkaz:
https://doaj.org/article/d47fc4e2cc244f8d8109bd4b0197ce3c
Autor:
Blanca Soler Palacios, Ricardo Villares, Pilar Lucas, José Miguel Rodríguez-Frade, Ana Cayuela, Jonathan G. Piccirillo, Manuel Lombardía, David Delgado Gestoso, Miguel Fernández-García, Cristina Risco, Coral Barbas, Fernando Corrales, Carlos Oscar S. Sorzano, Nuria Martínez-Martín, José Javier Conesa, Francisco J. Iborra, Mario Mellado
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMacrophages are a heterogeneous population of innate immune cells that support tissue homeostasis through their involvement in tissue development and repair, and pathogen defense. Emerging data reveal that metabolism may control macrophag
Externí odkaz:
https://doaj.org/article/e00655a008f84d658709283a0e506648
Autor:
Ana Martínez-Riaño, Nuria Martínez-Martín, María Jesús Martín-Bermejo, Balbino Alarcón, Elena R. Bovolenta, Paola Bovolenta, Clara L. Oeste, Martin R Turner, Pilar Mendoza
Publikováno v:
EMBO Reports
Successful vaccines rely on activating a functional humoral response that results from promoting a proper germinal center (GC) reaction. Key in this process is the activation of follicular B cells that need to acquire antigens and to present them to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c939e8495ff877665b1089600fd88f
https://doi.org/10.15252/embr.201846016
https://doi.org/10.15252/embr.201846016
Autor:
Clara L. Oeste, Nuria Martínez-Martín, Pilar Delgado, Pilar Mendoza, Elena R. Bovolenta, Balbino Alarcón, Tomohiro Kurosaki, Pablo Hernansanz-Agustín, Xosé R. Bustelo, Manuel D. Díaz-Muñoz, Antonio Martínez-Ruiz, Isabel Fernández-Pisonero, Eugenio Santos, Ester Castellano, Diego Alonso-López, Diana Reyes-Garau
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Upon antigen recognition within peripheral lymphoid organs, B cells interact with T cells and other immune cells to transiently form morphological structures called germinal centers (GCs), which are required for B cell clonal expansion, immunoglobuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cfc400395b57c24659958da85f59ce
http://hdl.handle.net/10261/169371
http://hdl.handle.net/10261/169371
Autor:
Balbino Alarcón, Nuria Martínez-Martín
Publikováno v:
Small GTPases
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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Activating mutations and overexpression of classical Ras subfamily members (K-Ras, N-Ras and H-Ras) have been widely investigated as key events in the development of human cancers. The role in cancer of its closest relatives, the Ras-related (RRas) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379469a3c976b339267af500d5a261b4
https://doi.org/10.4161/sgtp.19138
https://doi.org/10.4161/sgtp.19138
Publikováno v:
Immunology. 133:420-425
The immunological synapse forms as a result of the tight apposition of a T cell with an antigen-presenting cell (APC) and it is the site where the T-cell receptor (TCR) is triggered by its antigen ligand, the peptide-MHC complex present in the APC me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::392f3b9d1291b77eb6c0115e59f878a2
https://doi.org/10.1111/j.1365-2567.2011.03458.x
https://doi.org/10.1111/j.1365-2567.2011.03458.x
Autor:
Enrique Raya Alvarez, Nuria Martínez Martín, Juan de Dios Luna, Manuel Muñoz Torres, Francisca López Rodríguez, Jorge González Calvin, Alicia Conde Valero, Pedro Mezquita Raya, Fernando Escobar Jiménez, Norberto Ortego Centeno
Publikováno v:
Medicina Clínica. 119:85-89
Fundamento En la actualidad, la deficiencia grave de vitamina D es infrecuente en la mayoria de los paises desarrollados. Sin embargo, la prevalencia del deficit subclinico de vitamina D (insuficiencia de vitamina D [IVD]) es mas elevada y puede cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97ed5afa13390138356896514f454293
https://doi.org/10.1016/s0025-7753(02)73327-7
https://doi.org/10.1016/s0025-7753(02)73327-7
Autor:
Miguel Martí-Cabrera, José Manuel Morales, Daniel Monleon, Nadezda Apostolova, Nuria Martínez-Martín, Ana Blas-Garcia
Publikováno v:
International Journal of Molecular Medicine.
AMP-activated protein kinase (AMPK) is a metabolic master switch expressed in a great number of cells and tissues. AMPK is thought to modulate the cellular response to different stresses that increase cellular AMP concentration. The adenosine analog,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a281f041a8312295495762bca32af1
https://doi.org/10.3892/ijmm.2011.802
https://doi.org/10.3892/ijmm.2011.802
Autor:
María Teresa Bobes Bascarán, Julio Bobes, Pilar A. Saiz, Celso Arango, David Fraguas, María Paz García-Portilla, Nuria Martínez-Martín
Publikováno v:
The Journal of nervous and mental disease. 199(9)
This study assessed the relationship between self-perceived clinical and social needs and aggressive behavior in outpatients with schizophrenia. A total of 895 outpatients with schizophrenia were enrolled. The presence of aggressive episodes was asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47335ddd519993b2918e4a22478034f
https://pubmed.ncbi.nlm.nih.gov/21878780
https://pubmed.ncbi.nlm.nih.gov/21878780
Autor:
Xosé R. Bustelo, Pilar Delgado, Andrey S. Shaw, Bonnie Huang, Martin R Turner, John E. Heuser, Balbino Alarcón, Nuria Martínez-Martín, Darrell J. Irvine, Saso Cemerski, Elena Fernández-Arenas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Immunity; Vol 35
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Immunity; Vol 35
The immunological synapse (IS) serves a dual role for sustained T cell receptor (TCR) signaling and for TCR downregulation. TC21 (Rras2) is a RRas subfamily GTPase that constitutively associates with the TCR and is implicated in tonic TCR signaling b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2799af132794e75a13fb25b5f6c5eb43
http://hdl.handle.net/10261/57533
http://hdl.handle.net/10261/57533