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pro vyhledávání: '"Nuria Lopez"'
Akademický článek
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Autor:
Marta Dafne Cabañero-Navalon, Victor Garcia-Bustos, Héctor Balastegui-Martin, Carmen Bracke, Lourdes Mateu, Xavier Solanich, Juan Luis Carrillo-Linares, Angel Robles-Marhuenda, Francesc Puchades, Ana Pelaez Ballesta, Nuria Lopez-Osle, Miguel Ángel Torralba-Cabeza, Ana María Bielsa Masdeu, Jorge Gil Niño, Nuria Tornador Gaya, Guillem Pascual Castellanos, Rosario Sánchez-Martínez, José Manuel Barragán-Casas, Andrés González-García, José Luis Patier de la Peña, Daniel López-Wolf, Antonia Mora Rufete, Alba Canovas Mora, Pedro Moral Moral
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCommon Variable Immunodeficiency (CVID) represents a heterogenic group of primary immunodeficiencies (PID) characterized by impaired antibody production and susceptibility to infections. Non-infectious complications, such as autoimmune dise
Externí odkaz:
https://doaj.org/article/f5f9e7f255ce48fbb5690c874df847b0
Autor:
Christin Krause, Jan H Britsemmer, Miriam Bernecker, Anna Molenaar, Natalie Taege, Nuria Lopez-Alcantara, Cathleen Geißler, Meike Kaehler, Katharina Iben, Anna Judycka, Jonas Wagner, Stefan Wolter, Oliver Mann, Paul Pfluger, Ingolf Cascorbi, Hendrik Lehnert, Kerstin Stemmer, Sonja C Schriever, Henriette Kirchner
Publikováno v:
eLife, Vol 12 (2024)
Background: The development of obesity-associated comorbidities such as type 2 diabetes (T2D) and hepatic steatosis has been linked to selected microRNAs in individual studies; however, an unbiased genome-wide approach to map T2D induced changes in t
Externí odkaz:
https://doaj.org/article/61a65780677c4d41af349194722f905a
Autor:
Sujath Abbas, Oriol Pich, Ginny Devonshire, Shahriar A. Zamani, Annalise Katz-Summercorn, Sarah Killcoyne, Calvin Cheah, Barbara Nutzinger, Nicola Grehan, Nuria Lopez-Bigas, OCCAMS Consortium, Rebecca C. Fitzgerald, Maria Secrier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract A variety of mutational processes drive cancer development, but their dynamics across the entire disease spectrum from pre-cancerous to advanced neoplasia are poorly understood. We explore the mutagenic processes shaping oesophageal adenocar
Externí odkaz:
https://doaj.org/article/80b7ae7055464931a7d92bf9f8491937
Autor:
Riccardo Dore, Laura Watson, Stefanie Hollidge, Christin Krause, Sarah Christine Sentis, Rebecca Oelkrug, Cathleen Geißler, Kornelia Johann, Mehdi Pedaran, Greta Lyons, Nuria Lopez-Alcantara, Julia Resch, Friedhelm Sayk, Karl Alexander Iwen, Andre Franke, Teide Jens Boysen, Jeffrey W. Dalley, Kristina Lorenz, Carla Moran, Kirsten L. Rennie, Anders Arner, Henriette Kirchner, Krishna Chatterjee, Jens Mittag
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Mutations in thyroid hormone receptor α1 (TRα1) cause Resistance to Thyroid Hormone α (RTHα), a disorder characterized by hypothyroidism in TRα1-expressing tissues including the heart. Surprisingly, we report that treatment of RTHα pat
Externí odkaz:
https://doaj.org/article/39463f62342d495e8fd52912473497e2
Autor:
Nuria Lopez-Alcantara, Rebecca Oelkrug, Sarah Christine Sentis, Henriette Kirchner, Jens Mittag
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108064- (2023)
Summary: Agonists for thyroid hormone receptor β (TRβ) show promise in preclinical studies and clinical trials to improve non-alcoholic fatty liver disease. A recent study on human livers, however, revealed reduced TRβ expression in non-alcoholic
Externí odkaz:
https://doaj.org/article/4fe36f533d204854a3e96c804fdc529a
Autor:
Santiago Demajo, Juan Enric Ramis-Zaldivar, Ferran Muiños, Miguel Grau, Abel González-Pérez, Nuria Lopez Bigas
Publikováno v:
HemaSphere, Vol 7, p e91430c6 (2023)
Externí odkaz:
https://doaj.org/article/22cc55b98dfe449691ce1e9774e232a3
Autor:
Marta Palafox, Laia Monserrat, Meritxell Bellet, Guillermo Villacampa, Abel Gonzalez-Perez, Mafalda Oliveira, Fara Brasó-Maristany, Nusaibah Ibrahimi, Srinivasaraghavan Kannan, Leonardo Mina, Maria Teresa Herrera-Abreu, Andreu Òdena, Mònica Sánchez-Guixé, Marta Capelán, Analía Azaro, Alejandra Bruna, Olga Rodríguez, Marta Guzmán, Judit Grueso, Cristina Viaplana, Javier Hernández, Faye Su, Kui Lin, Robert B. Clarke, Carlos Caldas, Joaquín Arribas, Stefan Michiels, Alicia García-Sanz, Nicholas C. Turner, Aleix Prat, Paolo Nuciforo, Rodrigo Dienstmann, Chandra S. Verma, Nuria Lopez-Bigas, Maurizio Scaltriti, Monica Arnedos, Cristina Saura, Violeta Serra
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
CDK4/6 inhibitor resistance is common in breast cancer. Here, the authors show that p16 overexpression may be linked to reduced efficacy of CDK4/6 inhibition, and show that the combination with PI3K inhibitors may increase anti-tumour effects.
Externí odkaz:
https://doaj.org/article/c3a330e420d34dc992aab0ec2b80986a
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Identifying the genetic drivers of clonal haematopoiesis (CH) has been challenging due to their low frequencies and a lack of adequate tools. Here, the authors use a reverse calling to detect blood somatic mutations and the IntOGen pipeline to identi
Externí odkaz:
https://doaj.org/article/7cdd08da9e5f4c1dab238047d9bd0d31
Autor:
Paulston, Christina Bratt
Publikováno v:
Language, 1997 Sep 01. 73(3), 657-658.
Externí odkaz:
https://www.jstor.org/stable/415915