Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nuria Lara-Castillo"'
Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
Autor:
Erica Jackson, Nuria Lara-Castillo, Mohammed P. Akhter, Mark Dallas, JoAnna M. Scott, Thiagarajan Ganesh, Mark L. Johnson
Publikováno v:
Bone Reports, Vol 15, Iss , Pp 101129- (2021)
Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ov
Externí odkaz:
https://doaj.org/article/2a032dfe8d8b4b2d88b9ef33de850cf2
Autor:
Hammad Mumtaz, Mark Dallas, Mark Begonia, Nuria Lara-Castillo, JoAnna M. Scott, Mark L. Johnson, Thiagarajan Ganesh
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100266- (2020)
Aging is known to reduce bone quality and bone strength. We sought to determine how aging affects the biomechanical and architectural properties of various long bones, and if sex influences age related differences/changes. While researchers have exte
Externí odkaz:
https://doaj.org/article/62869c1cbc7244288b4aa9b2c84c0c6f
Autor:
Nuria Lara-Castillo
Publikováno v:
Applied Sciences, Vol 11, Iss 10, p 4439 (2021)
Estrogen plays important roles in bone homeostasis throughout a person’s life, including longitudinal bone growth, bone healing, and adaptation to mechanical forces. Estrogen exerts its action by binding to its multiple receptors in the cell membra
Externí odkaz:
https://doaj.org/article/4223758b13304176b39367d6dc7b8bef
Publikováno v:
Biomedicines, Vol 5, Iss 4, p 62 (2017)
Osteoporosis and sarcopenia are age-related musculoskeletal pathologies that often develop in parallel. Osteoporosis is characterized by a reduced bone mass and an increased fracture risk. Sarcopenia describes muscle wasting with an increasing risk o
Externí odkaz:
https://doaj.org/article/33eb2bbed9bf403c97551989c8805d92
Autor:
Nuria Lara-Castillo, JoAnna M. Scott, Hammad Mumtaz, Thiagarajan Ganesh, Mark L. Johnson, Mark T. Begonia, Mark Dallas
Publikováno v:
Aging (Albany NY)
We examined the changes in mechanical strain response of male and female mouse tibia and ulna, using axial compression tests, to assess age-related changes in tibiae and ulnae by a non-contact strain measurement technique called the digital image cor
Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
Autor:
Mark L. Johnson, Nuria Lara-Castillo, Thiagarajan Ganesh, JoAnna M. Scott, Erica Jackson, Mark Dallas, Mohammed P. Akhter
Publikováno v:
Bone Reports
Bone Reports, Vol 15, Iss, Pp 101129-(2021)
Bone Reports, Vol 15, Iss, Pp 101129-(2021)
Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ov
Autor:
Nuria Lara-Castillo, Mark L. Johnson
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: The purpose of this review is to describe the current state of our thinking regarding bone-muscle interactions beyond the mechanical perspective. RECENT FINDINGS: Recent and prior evidence has begun to dissect many of the molecular
Publikováno v:
Bone
Osteocytes form over ninety percent of the bone cells and are postulated to be mechanosensors responsible for regulating the function of osteoclasts and osteoblasts in bone modeling and remodeling. Physical activity results in mechanical loading on t
Autor:
Mark L. Johnson, Hammad Mumtaz, Mark T. Begonia, JoAnna M. Scott, Nuria Lara-Castillo, Thiagarajan Ganesh, Mark Dallas
Publikováno v:
Bone Reports
Bone Reports, Vol 12, Iss, Pp 100266-(2020)
Bone Reports, Vol 12, Iss, Pp 100266-(2020)
Aging is known to reduce bone quality and bone strength. We sought to determine how aging affects the biomechanical and architectural properties of various long bones, and if sex influences age related differences/changes. While researchers have exte
Autor:
JoAnna M. Scott, Ganesh Thiagarajan, Nuria Lara-Castillo, Mark Dallas, Mark L. Johnson, Mark T. Begonia
Publikováno v:
Journal of Biomechanical Engineering. 140
The determination of the elastic modulus of bone is important in studying the response of bone to loading and is determined using a destructive three-point bending method. Reference point indentation (RPI), with one cycle of indentation, offers a non