Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Nuria Izquierdo-Useros"'
Autor:
Carlos Ávila-Nieto, Júlia Vergara-Alert, Pep Amengual-Rigo, Erola Ainsua-Enrich, Marco Brustolin, María Luisa Rodríguez de la Concepción, Núria Pedreño-Lopez, Jordi Rodon, Victor Urrea, Edwards Pradenas, Silvia Marfil, Ester Ballana, Eva Riveira-Muñoz, Mònica Pérez, Núria Roca, Ferran Tarrés-Freixas, Guillermo Cantero, Anna Pons-Grífols, Carla Rovirosa, Carmen Aguilar-Gurrieri, Raquel Ortiz, Ana Barajas, Benjamin Trinité, Rosalba Lepore, Jordana Muñoz-Basagoiti, Daniel Perez-Zsolt, Nuria Izquierdo-Useros, Alfonso Valencia, Julià Blanco, Victor Guallar, Bonaventura Clotet, Joaquim Segalés, Jorge Carrillo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Safe and effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are crucial to fight against the coronavirus disease 2019 pandemic. Most vaccines are based on a mutated version of the Spike glycoprotein [K986P/V987P
Externí odkaz:
https://doaj.org/article/417894952ca54f88947455ec8d336df7
Autor:
Patricia Resa-Infante, Itziar Erkizia, Xabier Muñiz-Trabudua, Federica Linty, Arthur E.H. Bentlage, Daniel Perez-Zsolt, Jordana Muñoz-Basagoiti, Dàlia Raïch-Regué, Nuria Izquierdo-Useros, Theo Rispens, Gestur Vidarsson, Javier Martinez-Picado
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116726- (2024)
New therapies to treat or prevent viral infections are essential, as recently observed during the COVID-19 pandemic. Here, we propose a therapeutic strategy based on monoclonal antibodies that block the specific interaction between the host receptor
Externí odkaz:
https://doaj.org/article/2cd5e7bdb8cb4fdfa21bfaa53c58bcff
Autor:
Carla Usai, Erola Ainsua-Enrich, Victor Urrea Gales, Edwards Pradenas, Cristina Lorca-Oró, Ferran Tarrés-Freixas, Núria Roca, Mónica Pérez, Carlos Ávila-Nieto, María Luisa Rodríguez de la Concepción, Núria Pedreño-Lopez, Julieta Carabelli, Benjamin Trinité, Ester Ballana, Eva Riveira-Muñoz, Nuria Izquierdo-Useros, Bonaventura Clotet, Julià Blanco, Victor Guallar, Guillermo Cantero, Júlia Vergara-Alert, Jorge Carrillo, Joaquim Segalés
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Age is associated with reduced efficacy of vaccines and linked to higher risk of severe COVID-19. Here we determined the impact of ageing on the efficacy of a SARS-CoV-2 vaccine based on a stabilised Spike glycoprotein (S-29) that had previo
Externí odkaz:
https://doaj.org/article/f305a783ac09456b913d3b908a30b8e8
Autor:
Leire de Campos-Mata, Benjamin Trinité, Andrea Modrego, Sonia Tejedor Vaquero, Edwards Pradenas, Anna Pons-Grífols, Natalia Rodrigo Melero, Diego Carlero, Silvia Marfil, César Santiago, Dàlia Raïch-Regué, María Teresa Bueno-Carrasco, Ferran Tarrés-Freixas, Ferran Abancó, Victor Urrea, Nuria Izquierdo-Useros, Eva Riveira-Muñoz, Ester Ballana, Mónica Pérez, Júlia Vergara-Alert, Joaquim Segalés, Carlo Carolis, Rocío Arranz, Julià Blanco, Giuliana Magri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Here we report the characterization of 17T2, a SARS-CoV-2 pan-neutralizing human monoclonal antibody isolated from a COVID-19 convalescent individual infected during the first pandemic wave. 17T2 is a class 1 VH1-58/κ3-20 antibody, derived
Externí odkaz:
https://doaj.org/article/e88c94774f434c16bec8caaf30b4258f
Autor:
Cristina Agustí, Héctor Martínez-Riveros, Àgueda Hernández-Rodríguez, Cristina Casañ, Yesika Díaz, Lucía Alonso, Elisa Martró, Jordana Muñoz-Basagoiti, Marçal Gallemí, Cinta Folch, Ibrahim Sönmez, Héctor Adell, Marta Villar, Alexia París de León, Sandra Martinez-Puchol, A. C. Pelegrin, Daniel Perez-Zsolt, Dàlia Raïch-Regué, Rubén Mora, Luis Villegas, Bonaventura Clotet, Nuria Izquierdo-Useros, Pere-Joan Cardona, Jordi Casabona
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The recent monkeypox virus (MPXV) outbreak was of global concern and has mainly affected gay, bisexual and other men who have sex with men (GBMSM). Here we assess prevalence of MPXV in high-risk populations of GBMSM, trans women (TW) and non
Externí odkaz:
https://doaj.org/article/bcf56eebf3c241cf8c16c08da6595f07
Safety and immunogenicity of a recombinant protein RBD fusion heterodimer vaccine against SARS-CoV-2
Autor:
Lorna Leal, Judit Pich, Laura Ferrer, Jocelyn Nava, Ruth Martí-Lluch, Ignasi Esteban, Edwards Pradenas, Dàlia Raïch-Regué, Antoni Prenafeta, Karla Escobar, Carmen Pastor, Marc Ribas-Aulinas, Benjamin Trinitè, Jordana Muñoz-Basagoiti, Gemma Domenech, Bonaventura Clotet, Júlia Corominas, Aida Corpes-Comes, Carme Garriga, Antonio Barreiro, Nuria Izquierdo-Useros, Joan Albert Arnaiz, Alex Soriano, José Ríos, Marga Nadal, Montserrat Plana, Julià Blanco, Teresa Prat, Elia Torroella, Rafel Ramos, HIPRA-HH-1 study group
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract In response to COVID-19 pandemic, we have launched a vaccine development program against SARS-CoV-2. Here we report the safety, tolerability, and immunogenicity of a recombinant protein RBD fusion heterodimeric vaccine against SARS-CoV-2 (PH
Externí odkaz:
https://doaj.org/article/0a20f98d912343ffad1efe821c52c851
Autor:
Carlos Ávila-Nieto, Júlia Vergara-Alert, Pep Amengual-Rigo, Erola Ainsua-Enrich, Marco Brustolin, María Luisa Rodríguez de la Concepción, Núria Pedreño-Lopez, Jordi Rodon, Victor Urrea, Edwards Pradenas, Silvia Marfil, Ester Ballana, Eva Riveira-Muñoz, Mònica Pérez, Núria Roca, Ferran Tarrés-Freixas, Julieta Carabelli, Guillermo Cantero, Anna Pons-Grífols, Carla Rovirosa, Carmen Aguilar-Gurrieri, Raquel Ortiz, Ana Barajas, Benjamin Trinité, Rosalba Lepore, Jordana Muñoz-Basagoiti, Daniel Perez-Zsolt, Nuria Izquierdo-Useros, Alfonso Valencia, Julià Blanco, Bonaventura Clotet, Victor Guallar, Joaquim Segalés, Jorge Carrillo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Most COVID-19 vaccines are based on the SARS-CoV-2 Spike glycoprotein (S) or their subunits. However, S shows some structural instability that limits its immunogenicity and production, hampering the development of recombinant S-based vaccines. The in
Externí odkaz:
https://doaj.org/article/8d145e1f4f964517b358c973214ef36f
Autor:
Dalia Raïch-Regué, Raquel Tenorio, Isabel Fernández de Castro, Ferran Tarrés-Freixas, Martin Sachse, Daniel Perez-Zsolt, Jordana Muñoz-Basagoiti, Sara Y. Fernández-Sánchez, Marçal Gallemí, Paula Ortega-González, Alberto Fernández-Oliva, José A. Gabaldón, Estrella Nuñez-Delicado, Josefina Casas, Núria Roca, Guillermo Cantero, Mónica Pérez, Carla Usai, Cristina Lorca-Oró, Júlia-Vergara Alert, Joaquim Segalés, Jorge Carrillo, Julià Blanco, Bonaventura Clotet Sala, José P. Cerón-Carrasco, Nuria Izquierdo-Useros, Cristina Risco
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114997- (2023)
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. Starting from a list of 116 drug candidates, we used
Externí odkaz:
https://doaj.org/article/43071a8c278d405aba6d89d713f1ccbe
Autor:
Enric Gutiérrez-Martínez, Susana Benet Garrabé, Nicolas Mateos, Itziar Erkizia, Jon Ander Nieto-Garai, Maier Lorizate, Kyra JE Borgman, Carlo Manzo, Felix Campelo, Nuria Izquierdo-Useros, Javier Martinez-Picado, Maria F Garcia-Parajo
Publikováno v:
eLife, Vol 12 (2023)
The immunoglobulin-like lectin receptor CD169 (Siglec-1) mediates the capture of HIV-1 by activated dendritic cells (DCs) through binding to sialylated ligands. These interactions result in a more efficient virus capture as compared to resting DCs, a
Externí odkaz:
https://doaj.org/article/5f42cba530f24b06adcd14390473871e
Autor:
Carla Usai, Lola Pailler-García, Cristina Lorca-Oró, Leira Fernández-Bastit, Núria Roca, Marco Brustolin, Jordi Rodon, Mónica Pérez, Guillermo Cantero, Jorge Carrillo, Nuria Izquierdo-Useros, Julià Blanco, Bonaventura Clotet, Sebastián Napp, Joaquim Segalés, Júlia Vergara-Alert
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Rodents are widely used for the development of COVID-19-like animal models, the virological outcome being determined through several laboratory methods reported in the literature. Our objective was to assess the agreement between methods performed on
Externí odkaz:
https://doaj.org/article/6183a2bf82264843b731f345665bd757