Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nuria Bonifaci"'
Autor:
Mariann Unhjem Wiik, Mia Negline, Vidar Beisvåg, Matthew Clapham, Elizabeth Holliday, Nuria Dueñas, Joan Brunet, Marta Pineda, Nuria Bonifaci, Stefan Aretz, Hannah Klinkhammer, Isabel Spier, Claudia Perne, Andreas Mayr, Laura Valle, Jan Lubinski, Wenche Sjursen, Rodney J. Scott, Bente A. Talseth-Palmer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Lynch syndrome (LS) is characterised by an increased risk of developing colorectal cancer (CRC) and other extracolonic epithelial cancers. It is caused by pathogenic germline variants in DNA mismatch repair (MMR) genes or the EPCAM gene, lea
Externí odkaz:
https://doaj.org/article/3bbca34d382145c49f58eee7da4ddbdf
Autor:
Laura Devis‐Jauregui, August Vidal, Laura Plata‐Peña, Maria Santacana, Sandra García‐Mulero, Nuria Bonifaci, Eulàlia Noguera‐Delgado, Nuria Ruiz, Marta Gil, Eduard Dorca, Francisco J. Llobet, Laura Coll‐Iglesias, Katja Gassner, Maria Martinez‐Iniesta, Ruth Rodriguez‐Barrueco, Marc Barahona, Lola Marti, Francesc Viñals, Jordi Ponce, Rebeca Sanz‐Pamplona, Josep M. Piulats, Ana Vivancos, Xavier Matias‐Guiu, Alberto Villanueva, David Llobet‐Navas
Publikováno v:
Advanced Science, Vol 10, Iss 1, Pp n/a-n/a (2023)
Abstract Clinical management of endometrial cancer (EC) is handicapped by the limited availability of second line treatments and bona fide molecular biomarkers to predict recurrence. These limitations have hampered the treatment of these patients, wh
Externí odkaz:
https://doaj.org/article/88510e34e7fe4b8697754d4822ed3e67
A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG
Autor:
Ruth Rodríguez‐Barrueco, Jessica Latorre, Laura Devis‐Jáuregui, Aina Lluch, Nuria Bonifaci, Francisco J. Llobet, Mireia Olivan, Laura Coll‐Iglesias, Katja Gassner, Meredith L. Davis, José M. Moreno‐Navarrete, Anna Castells‐Nobau, Laura Plata‐Peña, Miki Dalmau‐Pastor, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, Maria Arnoriaga‐Rodríguez, Wifredo Ricart, José M. Fernández‐Real, José M. Silva, Francisco J. Ortega, David Llobet‐Navas
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Abstract The H19X‐encoded miR‐424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity
Externí odkaz:
https://doaj.org/article/e3f63b7bc662455caa34ba1b1fa999a2
Autor:
Sònia Gatius, Mariona Jove, Cristina Megino-Luque, Manel Albertí-Valls, Andree Yeramian, Nuria Bonifaci, Miquel Piñol, Maria Santacana, Irene Pradas, David Llobet-Navas, Reinald Pamplona, Xavier Matías-Guiu, Núria Eritja
Publikováno v:
Cancers, Vol 14, Iss 12, p 2842 (2022)
Metabolomic profiling analysis has the potential to highlight new molecules and cellular pathways that may serve as potential therapeutic targets for disease treatment. In this study, we used an LC-MS/MS platform to define, for the first time, the sp
Externí odkaz:
https://doaj.org/article/3b14f31e934d44c4813638f86cf175d5
Autor:
Pilar Mur, Nuria Bonifaci, Anna Díez-Villanueva, Elisabet Munté, Maria Henar Alonso, Mireia Obón-Santacana, Gemma Aiza, Matilde Navarro, Virginia Piñol, Joan Brunet, Ian Tomlinson, Gabriel Capellá, Victor Moreno, Laura Valle
Publikováno v:
Cancers, Vol 13, Iss 15, p 3857 (2021)
A large proportion of familial and/or early-onset cancer patients do not carry pathogenic variants in known cancer predisposing genes. We aimed to assess the contribution of previously validated low-risk colorectal cancer (CRC) alleles to familial/ea
Externí odkaz:
https://doaj.org/article/a0e3714dcb0a4b3f9847c442693402bd
Autor:
Nuria Dueñas, Hannah Klinkhammer, Nuria Bonifaci, Isabel Spier, Andreas Mayr, Emadeldin Hassanin, Anna Díez-Villanueva, Victor Moreno, Marta Pineda, Carlo Maj, Gabriel Capellá, Stefan Aretz, Joan Brunet
BackgroundPolygenic risk scores (PRS) have been used to stratify colorectal cancer (CRC) risk in the general population, whereas its role in Lynch syndrome (LS), the most common type of hereditary CRC, is still conflicting. We aimed to assess the abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57bcc5242e82cbf3a4367c34792f91e7
https://doi.org/10.1101/2023.04.20.23288850
https://doi.org/10.1101/2023.04.20.23288850
Autor:
Laura Devis‐Jauregui, August Vidal, Laura Plata‐Peña, Maria Santacana, Sandra García‐Mulero, Nuria Bonifaci, Eulàlia Noguera‐Delgado, Nuria Ruiz, Marta Gil, Eduard Dorca, Francisco J. Llobet, Laura Coll‐Iglesias, Katja Gassner, Maria Martinez‐Iniesta, Ruth Rodriguez‐Barrueco, Marc Barahona, Lola Marti, Francesc Viñals, Jordi Ponce, Rebeca Sanz‐Pamplona, Josep M. Piulats, Ana Vivancos, Xavier Matias‐Guiu, Alberto Villanueva, David Llobet‐Navas
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
Clinical management of endometrial cancer (EC) is handicapped by the limited availability of second line treatments and bona fide molecular biomarkers to predict recurrence. These limitations have hampered the treatment of these patients, whose survi
A microRNA cluster controls fat cell differentiation and adipose tissue expansion by regulating SNCG
Autor:
Ruth Rodríguez‐Barrueco, Jessica Latorre, Laura Devis‐Jáuregui, Aina Lluch, Nuria Bonifaci, Francisco J. Llobet, Mireia Olivan, Laura Coll‐Iglesias, Katja Gassner, Meredith L. Davis, José M. Moreno‐Navarrete, Anna Castells‐Nobau, Laura Plata‐Peña, Miki Dalmau‐Pastor, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, Maria Arnoriaga‐Rodríguez, Wifredo Ricart, José M. Fernández‐Real, José M. Silva, Francisco J. Ortega, David Llobet‐Navas
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
The H19X-encoded miR-424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity, while incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd31ca7603b3f84c28bd2b992ec8e2bb
http://hdl.handle.net/2445/189979
http://hdl.handle.net/2445/189979
Autor:
Isabel C. Lopez‐Mejia, Jordi Pijuan, Raúl Navaridas, Maria Santacana, Sònia Gatius, Ana Velasco, Gerard Castellà, Anaïs Panosa, Elisa Cabiscol, Miquel Pinyol, Laura Coll, Núria Bonifaci, Laura Plata Peña, August Vidal, Alberto Villanueva, Eloi Gari, David Llobet‐Navàs, Lluis Fajas, Xavier Matias‐Guiu, Andrée Yeramian
Publikováno v:
Molecular Oncology, Vol 17, Iss 1, Pp 98-118 (2023)
Uterine serous carcinoma (USC) is an aggressive form of endometrial cancer (EC), characterized by its high propensity for metastases. In fact, while endometrioid endometrial carcinoma (EEC), which accounts for 85% of EC, presents a good prognosis, US
Externí odkaz:
https://doaj.org/article/f663469d36c74406919fb1ffb516ab40
Autor:
Cristina Megino‐Luque, Pol Sisó, Natalia Mota‐Martorell, Raúl Navaridas, Inés de laRosa, Izaskun Urdanibia, Manel Albertí‐Valls, Maria Santacana, Miquel Pinyol, Núria Bonifaci, Anna Macià, David Llobet‐Navas, Sònia Gatius, Xavier Matias‐Guiu, Núria Eritja
Publikováno v:
Molecular Oncology, Vol 16, Iss 11, Pp 2235-2259 (2022)
AT‐rich interactive domain‐containing protein 1A (ARID1A) loss‐of‐function mutation accompanied by a loss of ARID1A protein expression is frequently observed in endometrial carcinomas. However, the molecular mechanisms linking these genetic c
Externí odkaz:
https://doaj.org/article/88829f0c96d5428fb487eeec1a5e9881