Výsledky vyhledávání - "Nurhainis Ogu Salim"

Akademický článek

Purifying and Characterizing Bacterially Expressed Soluble Lactate Dehydrogenase from Plasmodium knowlesi for the Development of Anti-Malarial Drugs

Autor: Nurhainis Ogu Salim, Fazia Adyani Ahmad Fuad, Farahayu Khairuddin, Wan Mohd Khairulikhsan Wan Seman, Mohd Anuar Jonet

Publikováno v: Molecules, Vol 26, Iss 21, p 6625 (2021)

Plasmodium lactate dehydrogenase (pLH) is one of the enzymes in glycolysis with potential target for chemotherapy. This study aimed to clone, overexpress and characterize soluble recombinant lactate dehydrogenase from Plasmodium knowlesi in a bacteri

Externí odkaz: https://doaj.org/article/358ce8e7ebae4496a21a8555d5ce7602

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Analogues of Oxamate, Pyruvate, and Lactate as Potential Inhibitors of Plasmodium knowlesi Lactate Dehydrogenase Identified Using Virtual Screening and Verified via Inhibition Assays

Autor: Fazia Adyani Ahmad Fuad, Nurhainis Ogu Salim

Publikováno v: Processes; Volume 10; Issue 11; Pages: 2443

Malaria management remains a challenge, due to the resistance of malaria parasites to current antimalarial agents. This resistance consequently delays the global elimination of malaria throughout the world. Hence, the demand is increasing for new and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c774fc4e4c1825e6fb14b6fc764386c2

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Purifying and Characterizing Bacterially Expressed Soluble Lactate Dehydrogenase from Plasmodium knowlesi for the Development of Anti-Malarial Drugs

Autor: Fazia Adyani Ahmad Fuad, Farahayu Khairuddin, Wan Mohd Khairulikhsan Wan Seman, Mohd Anuar Jonet, Nurhainis Ogu Salim

Publikováno v: Molecules
Volume 26
Issue 21
Molecules, Vol 26, Iss 6625, p 6625 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785b1213996767a12fe409bf7bde9cf9
http://europepmc.org/articles/PMC8588329

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Plasmodial enzymes in metabolic pathways as therapeutic targets and contemporary strategies to discover new antimalarial drugs: a review

Autor: Fazia Adyani Ahmad Fuad, Noor Azian Md Yusuf, Nurhainis Ogu Salim

Publikováno v: Asia Pacific Journal of Molecular Biology and Biotechnology. :38-53

Malaria continues to pose imminent threat to the world population, as the mortality rate associated with this disease remains high. Current treatment relies on antimalarial drugs such as Artemisinin Combination Therapy (ACT) are still effective throu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b748b06d53f0e51fa2eb704142759ec5
https://doi.org/10.35118/apjmbb.2019.027.4.05

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Genetic diversity of Plasmodium knowlesi among human and long-tailed macaque populations in Peninsular Malaysia: The utility of microsatellite markers

Autor: NoorAzian Md Yusuf, Mohd Ridzuan Mohd Abd Razak, Nurhainis Ogu Salim, Afiqah Saleh Huddin, Shamilah Hisam

Publikováno v: Infection, Genetics and Evolution. 75:103952

It has been discovered that Plasmodium knowlesi (P. knowlesi) is transmitted from macaque to man. Thus, the aim of the present study was to determine P. knowlesi genetic diversity in both human (n = 147) and long-tailed macaque (n = 26) samples from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390fd5dda3e50212191a9119170aef1c
https://doi.org/10.1016/j.meegid.2019.103952

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