Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nurgul Moldobaeva"'
Autor:
Sumegha Mitra, Michael S Wade, Xiaoguang Sun, Nurgul Moldobaeva, Carlos Flores, Shwu-Fan Ma, Wei Zhang, Joe G N Garcia, Jeffrey R Jacobson
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100169 (2014)
Growth arrest DNA damage inducible alpha (GADD45a) is a stress-induced gene we have shown to participate in the pathophysiology of ventilator-induced lung injury (VILI) via regulation of mechanical stress-induced Akt ubiquitination and phosphorylatio
Externí odkaz:
https://doaj.org/article/24da043a0c7746dc90cebb737aa101e5
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e105912 (2014)
Microtubules (MT) play a vital role in many cellular functions, but their role in peripheral actin cytoskeletal dynamics which is essential for control of endothelial barrier and monolayer integrity is less understood. We have previously described th
Externí odkaz:
https://doaj.org/article/8033e033c5924daebe24ecd67729a091
Publikováno v:
Cellular Signalling. 28:541-551
Endothelial cell (EC) barrier disruption induced by edemagenic agonists such as thrombin is a result of increased actomyosin contraction and enforcement of focal adhesions (FA) anchoring contracting stress fibers, which leads to cell retraction and f
Autor:
Luka Pocivavsek, Ka Yee C. Lee, Konstantin G. Birukov, Charles T.R. Heffern, Anna A. Birukova, Nurgul Moldobaeva, Valery N. Bochkov
Publikováno v:
Chemistry and Physics of Lipids. :9-19
The lipid membrane not only provides a rich interface with an array of receptor signaling complexes with which a cell communicates, but it also serves as a source of lipid derived bioactive molecules. In pathologic conditions of acute lung injury (AL
Autor:
Anita Kasa, Shwu Fan Ma, Djanybek Adyshev, Joe G.N. Garcia, Kyung Mi Kim, Alexander D. Verin, Steven M. Dudek, Nurgul Moldobaeva
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 305:L240-L255
Endothelial cell (EC) barrier disruption induced by inflammatory agonists such as thrombin leads to potentially lethal physiological dysfunction such as alveolar flooding, hypoxemia, and pulmonary edema. Thrombin stimulates paracellular gap and F-act
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 295:L612-L623
Mechanical ventilation at high tidal volumes compromises the blood-gas barrier and increases lung vascular permeability, which may lead to ventilator-induced lung injury and pulmonary edema. Using pulmonary endothelial cell (ECs) exposed to physiolog
Autor:
Grzegorz Gawlak, Katherine Higginbotham, Yufeng Tian, Nurgul Moldobaeva, Anna A. Birukova, Alok S. Shah
Publikováno v:
Cellular signalling. 26(11)
Previous reports described an important role of hepatocyte growth factor (HGF) in mitigation of pulmonary endothelial barrier dysfunction and cell injury induced by pathologic agonists and mechanical forces. HGF protective effects have been associate
Autor:
Xiaoguang Sun, Nurgul Moldobaeva, Brandon Mapes, Djanybek Adyshev, Joe G.N. Garcia, Venkateswaran Ramamoorthi Elangovan
Increased lung vascular permeability and alveolar edema are cardinal features of inflammatory conditions such as acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). We previously demonstrated that pre–B-cell colony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c901677586d0c65625023f180dfaca9a
https://europepmc.org/articles/PMC3930953/
https://europepmc.org/articles/PMC3930953/
Autor:
Brandon Mapes, Nurgul Moldobaeva, Venkateswaran Ramamoorthi Elangovan, Djanybek Adyshev, Joe G.N. Garcia
Publikováno v:
American journal of respiratory cell and molecular biology. 49(1)
Increased lung vascular permeability, the consequence of endothelial cell (EC) barrier dysfunction, is a cardinal feature of inflammatory conditions such as acute lung injury and sepsis and leads to lethal physiological dysfunction characterized by a
Autor:
Venkateswaran Ramamoorthi Elangovan, Djanybek Adyshev, Joe G.N. Garcia, Nurgul Moldobaeva, Steven M. Dudek
Publikováno v:
C71. MAJOR IMPACT OF MICRO-RNA FUNCTION.