Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nuray Gunduz"'
Autor:
Arafath K. Najumudeen, Sigrid K. Fey, Laura M. Millett, Catriona A. Ford, Kathryn Gilroy, Nuray Gunduz, Rachel A. Ridgway, Eve Anderson, Douglas Strathdee, William Clark, Colin Nixon, Jennifer P. Morton, Andrew D. Campbell, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Oncogenic KRAS mutations are well-described functionally and are known to drive tumorigenesis. Recent reports describe a significant prevalence of KRAS allelic imbalances or gene dosage changes in human cancers, including loss of the wild-ty
Externí odkaz:
https://doaj.org/article/cc435f850ded4ca6b07a54a34129b55d
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gunduz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d890b609d092453794d4b110a230e27b
Autor:
Dustin J. Flanagan, Raheleh Amirkhah, David F. Vincent, Nuray Gunduz, Pauline Gentaz, Patrizia Cammareri, Aoife J. McCooey, Amy M. B. McCorry, Natalie C. Fisher, Hayley L. Davis, Rachel A. Ridgway, Jeroen Lohuis, Joshua D. G. Leach, Rene Jackstadt, Kathryn Gilroy, Elisa Mariella, Colin Nixon, William Clark, Ann Hedley, Elke K. Markert, Douglas Strathdee, Laurent Bartholin, Keara L. Redmond, Emma M. Kerr, Daniel B. Longley, Fiona Ginty, Sanghee Cho, Helen G. Coleman, Maurice B. Loughrey, Alberto Bardelli, Timothy S. Maughan, Andrew D. Campbell, Mark Lawler, Simon J. Leedham, Simon T. Barry, Gareth J. Inman, Jacco van Rheenen, Philip D. Dunne, Owen J. Sansom
Publikováno v:
Flanagan, D J, Amirkhah, R, Vincent, D F, Gundaz, N, Gentaz, P, Cammareri, P, McCooey, A J, McCorry, A M B, Fisher, N C, Davis, H L, Ridgway, R A, Lohuis, J, Leach, J D G, Jackstadt, R, Gilroy, K, Mariella, E, Nixon, C, Clark, W, Hedley, A, Markert, E K, Strathdee, D, Bartholin, L, Redmond, K L, Kerr, E M, Longley, D B, Ginty, F, Cho, S, Coleman, H G, Loughrey, M B, Bardelli, A, Maughan, T S, Lawler, M, Leedham, S J, Barry, S T, Inman, G J, van Rheenen, J, Dunne, P D & Sansom, O J 2022, ' Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features ', Nature Communications, vol. 13, 7551 . https://doi.org/10.1038/s41467-022-35134-3
The pro-tumourigenic role of epithelial TGFβ signalling in colorectal cancer (CRC) is controversial. Here, we identify a cohort of born to be bad early-stage (T1) colorectal tumours, with aggressive features and a propensity to disseminate early, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e820d8d7048608ccd24d44e92c76aa2d
https://pure.qub.ac.uk/en/publications/3ebc086f-bb4c-4159-87d0-5a54515e53c9
https://pure.qub.ac.uk/en/publications/3ebc086f-bb4c-4159-87d0-5a54515e53c9
Autor:
Mustafa O. Guler, Ayse B. Tekinay, Sehmus Tohumeken, Nuray Gunduz, Mohammad Aref Khalily, Muhammed Burak Demircan, Turgay Tekinay
Publikováno v:
Biotechnology Journal
The design and development of novel adjuvants, which enhance, accelerate, and prolong the immune responses triggered by antigens, hold great importance for targeting infectious diseases and cancer. Here, we designed a biotinylated peptide amphiphile
Autor:
Mark T. Whary, Shinya Imada, Constantine Mylonas, Gizem Calibasi-Kocal, Yasemin Basbinar, Kunal Rai, Aviv Regev, Ömer H. Yilmaz, Nuray Gunduz, Chia-Wei Cheng, Vincent L. Butty, Richard O. Hynes, Marta Moreno-Serrano, Adam L. Haber, George Eng, Steffen Rickelt, Helen Piwnica-Worms, Khristian E. Bauer-Rowe, Laurie A. Boyer, Vikram Deshpande, Ameena M. Iqbal, Stuart S. Levine, Christopher Terranova, James G. Fox, Mehmet Sefa Ulutas, Maria M. Mihaylova, Surya Tripathi, Mari Mino-Kenudson, Moshe Biton, Liam T. Gaynor
Publikováno v:
PMC
Cell
Cell
Little is known about how metabolites couple tissue-specific stem cell function with physiology. Here we show that, in the mammalian small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), the gene encoding the rate-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0332aa08c2b93c199266d29e9f47ef
https://avesis.deu.edu.tr/publication/details/c0d69504-ac1b-4f87-8145-c29d14ceaa04/oai
https://avesis.deu.edu.tr/publication/details/c0d69504-ac1b-4f87-8145-c29d14ceaa04/oai
Autor:
M. Burak Demircan, Nuray Gunduz, Sehmus Tohumeken, Ayse B. Tekinay, Ahmet Topal, Gokhan Gunay, Turgay Tekinay, Mustafa O. Guler, M. Aref Khalily, Aykutlu Dana
Publikováno v:
Advanced Biosystems
The design and development of vaccines, which can induce cellular immunity, particularly CD8+ T cells hold great importance since these cells play crucial roles against cancers and viral infections. Covalent conjugation of antigen and adjuvant molecu
Publikováno v:
Scientific Reports
Understanding the toxicity of nanomaterials remains largely limited to acute cellular response, i.e., short-term in vitro cell-death based assays, and analyses of tissue- and organ-level accumulation and clearance patterns in animal models, which hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f37b5d3aab7d15368f41ba845187ce
https://hdl.handle.net/11693/37256
https://hdl.handle.net/11693/37256
Publikováno v:
Therapeutic Nanomaterials
Chapter 11 This chapter overviews the attempts in understanding the biocompatibility of nanomaterials and provides an account of how these views changed in light of recent findings, with emphasis on the methodology used in nanotoxicology studies. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3dc066b6c017c39d51e8215c396aa8
https://hdl.handle.net/11693/50933
https://hdl.handle.net/11693/50933
Publikováno v:
Scientific Reports
Extracellular matrix (ECM) is crucial for the coordination and regulation of cell adhesion, recruitment, differentiation and death. Therefore, equilibrium between cell-cell and cell-matrix interactions and matrix-associated signals are important for
Autor:
Handan Kayhan, Aykutlu Dana, Ilghar Orujalipoor, Mustafa O. Guler, Nuray Gunduz, Sehmus Tohumeken, Goksu Cinar, Tuncay Delibasi, Ayse B. Tekinay, Semra Ide, Rashad Mammadov, Melis Goktas, Ahmet Topal
Publikováno v:
Scientific Reports
Europe PubMed Central
Europe PubMed Central
Synthetic vaccines utilize viral signatures to trigger immune responses. Although the immune responses raised against the biochemical signatures of viruses are well characterized, the mechanism of how they affect immune response in the context of phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30aec5f34aca2e7c065d4fd3540ec99
http://hdl.handle.net/11655/15450
http://hdl.handle.net/11655/15450