Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Nur Salwani Bakar"'
1
Akademický článek
Association between genetic polymorphisms and other attributing factors with lipid profiles among statin users: a cross-sectional retrospective study
Autor: Amirul Faez Shamsudin, Sarina Sulong, Imran Ahmad, Nur Salwani Bakar
Publikováno v: Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Statins are well known for their efficacy to improve lipid profiles. Their efficacy varies between individuals and can be modified by patient factors such as genetic polymorphisms. This study used a cross-sectional retrospective d
Externí odkaz: https://doaj.org/article/750f52eefc474740acdad5709b20156d
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2
Akademický článek
Association of single nucleotide polymorphism at BMP2 gene with iron deficiency status among anaemic patients in Hospital Universiti Sains Malaysia
Autor: Nur Ain Azman, Zefarina Zulkafli, Nur Salwani Bakar, Mat Ghani Siti Nor Assyuhada, Siti Nur Nabeela A’ifah Mohammad
Publikováno v: Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Iron deficiency contributes for over half of all anaemia cases, especially among women and children. Iron deficiency anaemia remains a serious public health concern worldwide. The aim of this study is to determine the association
Externí odkaz: https://doaj.org/article/473279cad68c4ab4baad438441aab206
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3
Akademický článek
Detection of BCL11A, HMIP, and XmnI polymorphisms among anemic pregnant women in hospital Universiti Sains Malaysia
Autor: Yousef Saeed Mohammad Abu Za'ror, Siti Nor Assyuhada Mat Ghani, Nur Salwani Bakar, Zefarina Zulkafli, Maryam Azlan
Publikováno v: Journal of Applied Hematology, Vol 13, Iss 4, Pp 183-191 (2022)
BACKGROUND: Anemia is one of the most common conditions in women during pregnancy. Fetal hemoglobin (HbF) levels are usually 3.2%) and normal HbA2 level (≤3.2%) to detect mutation at b-globin gene cluster. Allelic discrimination for rs1186868, rs93
Externí odkaz: https://doaj.org/article/cd08dd20e2404236a0630b1ef3356644
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5
Genetic and gender factor affect lipid profiles of patients receiving statin treatment in the east coast region of Peninsular Malaysia
Autor: Amirul Faez Shamsudin, Nur Salwani Bakar
Aim: This study was conducted to evaluate the impact of genetic polymorphisms on lipid profiles of statin users. Methods: This retrospective cross-sectional study involved 229 hyperlipidaemic statin users in east coast region of Peninsular Malaysia.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ed46e7b3b84e3198935ef01793645f2
https://doi.org/10.22541/au.166721405.51189611/v1
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6
Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean
Autor: Nur Salwani Bakar
Publikováno v: Drug metabolism and personalized therapyReferences.
Compared to Europe, data on genetic variation in genes transcribing drug metabolizing enzymes among Asian is limited due to ethnic diversity. Here we compare frequencies for clinically relevant single nucleotide polymorphism (SNP) commonly observed i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9fc1c6c2bb3e6f1388536caf05bf4e
https://pubmed.ncbi.nlm.nih.gov/33735954
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7
Genetic and Clinical Factors Are Associated With Statin-Related Myotoxicity of Moderate Severity: A Case-Control Study
Autor: Ann K. Daly, Dermot Neely, Farhad Kamali, Peter Avery, Colin D.A. Brown, Nur Salwani Bakar
Publikováno v: Clinical Pharmacology & Therapeutics. 104:178-187
We evaluated the contribution of patient-specific clinical and genetic factors to statin-related muscle toxicity (SRM) without a significant creatine kinase elevation (125 cases related to simvastatin or atorvastatin and 481 controls). The associatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6e7929b096d87ea7cfced15970c67a
https://doi.org/10.1002/cpt.887
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8
The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule
Autor: Ellen van Loon, Abigail M. Dalzell, Nur Salwani Bakar, Colin D.A. Brown, Git Chung, Sarah Jenkinson
Publikováno v: Pflügers Archiv - European Journal of Physiology. 464:601-611
Acquiring a mechanistic understanding of the processes underlying the renal clearance of drug molecules in man has been hampered by a lack of robust in vitro models of human proximal tubules. Several human renal epithelial cell lines derived from the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9770d817d2f4afe8b9e7c0bddb2c8ebd
https://doi.org/10.1007/s00424-012-1163-2
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