Výsledky vyhledávání - "Nur Masirah M. Zain"

Akademický článek

Regulation, risk and safety of Faecal Microbiota Transplant

Autor: Blair Merrick, Liz Allen, Nur Masirah M Zain, Ben Forbes, Debbie L. Shawcross, Simon D. Goldenberg

Publikováno v: Infection Prevention in Practice, Vol 2, Iss 3, Pp 100069- (2020)

Summary: From its origins as a left-field, experimental, and even “maverick” intervention, faecal microbiota transplantation (FMT) is now a well-recognised, accepted, and potentially life-saving therapeutic strategy, for the management of recurre

Externí odkaz: https://doaj.org/article/048c926453364bf5a85e204b597f0f98

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Akademický článek

The airways microbiome of individuals with asthma treated with high and low doses of inhaled corticosteroids.

Autor: Matthew J Martin, Nur Masirah M Zain, Glenn Hearson, Damian W Rivett, Garrit Koller, David J Wooldridge, Graham Rose, Saheer E Gharbia, Ben Forbes, Kenneth D Bruce, Tim W Harrison

Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0244681 (2020)

BackgroundInhaled corticosteroids (ICS) are the mainstay of asthma treatment, but evidence suggests a link between ICS usage and increased rates of respiratory infections. We assessed the composition of the asthmatic airways microbiome in asthma pati

Externí odkaz: https://doaj.org/article/74d6cacfddb444b49372c25f98179133

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Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis

Autor: Nur Masirah M. Zain, Alan J. Knox, Edward F. Nash, Paul Williams, Karmel Webb, Alan R. Smyth, Miguel Cámara, Helen L. Barr, Douglas L Forrester, Nigel Halliday, Andrew W. Fogarty, Joanna L. Whitehouse, Kenneth D. Bruce

Publikováno v: Journal of Cystic Fibrosis. 21:626-629

Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs) that are detectable in the sputum of adults with cystic fibrosis (CF) and who have pulmonary infection with this opportunistic pathogen. This study aimed to det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d77737a03451a1465c036f64acf9ca
https://doi.org/10.1016/j.jcf.2021.08.030

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Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis

Autor: Karmel Webb, Nur Masirah M. Zain, Iain Stewart, Andrew Fogarty, Edward F. Nash, Joanna L. Whitehouse, Alan R. Smyth, Andrew K. Lilley, Alan Knox, Paul Williams, Miguel Cámara, Kenneth Bruce, Helen L. Barr

Although anaerobic bacteria exist in abundance in cystic fibrosis (CF) airways, their role in disease progression is poorly understood. We hypothesized that the presence and relative abundance of the most prevalent, live, anaerobic bacteria in sputum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7223e3f1d0695073b19741fb706957
http://hdl.handle.net/10044/1/98252

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2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis

Autor: Paul Williams, David A. Barrett, Nigel Halliday, Edward F. Nash, Alan J. Knox, Karmel Webb, Nur Masirah M. Zain, Douglas L. Forrester, Alan R. Smyth, Kenneth D. Bruce, Helen L. Barr, Iain A. Stewart, David Honeybourne, Andrew W. Fogarty, Miguel Cámara, Joanna L. Whitehouse

Publikováno v: Journal of Medical Microbiology. 70

Introduction. Pseudomonas aeruginosa produces quorum sensing signalling molecules including 2-alkyl-4-quinolones (AQs), which regulate virulence factor production in the cystic fibrosis (CF) airways. Hypothesis/Gap statement. Culture can lead to cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2eb9b45599d2fcf9c2c94c21cdcb5c0c
https://doi.org/10.1099/jmm.0.001420

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2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent

Autor: Nur Masirah M, Zain, Karmel, Webb, Iain, Stewart, Nigel, Halliday, David A, Barrett, Edward F, Nash, Joanna L, Whitehouse, David, Honeybourne, Alan R, Smyth, Douglas L, Forrester, Alan J, Knox, Paul, Williams, Andrew, Fogarty, Miguel, Cámara, Kenneth D, Bruce, Helen L, Barr

Publikováno v: J Med Microbiol

INTRODUCTION: Pseudomonas aeruginosa produces quorum sensing signalling molecules including 2-alkyl-4-quinolones (AQs), which regulate virulence factor production in the cystic fibrosis (CF) airways. HYPOTHESIS/GAP STATEMENT: Culture can lead to cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::decd7f3889485482020ce8ebe63604ba
https://pubmed.ncbi.nlm.nih.gov/34596013

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Antibiotic-in-Cyclodextrin-in-Liposomes: Formulation Development and Interactions with Model Bacterial Membranes

Autor: Luke A. Clifton, Maximilian W. A. Skoda, Nur Masirah M. Zain, Margarita Valero, Cécile A. Dreiss, Richard D. Harvey, Arcadia Woods, Kalliopi-Kelli A. Vandera, Kenneth D. Bruce, Khondaker M. Rahman, Gustavo González-Gaitano, Pietro Picconi

Publikováno v: Vandera, K-K A, Picconi, P, Valero, M, González-Gaitano, G, Woods, A, Zain, N M, Bruce, K, Clifton, L A, Skoda, M W A, Rahman, K M, Harvey, R D & Dreiss, C 2020, ' Antibiotic-in-cyclodextrin-in-liposomes : formulation development and interactions with model bacterial membranes ', Molecular Pharmaceutics, vol. 17, no. 7, pp. 2354-2369 . https://doi.org/10.1021/acs.molpharmaceut.0c00096

Gram-negative bacteria possess numerous defenses against antibiotics, due to the intrinsic permeability barrier of their outer membrane (OM), explaining the recalcitrance of some common and life-threatening infections. We report the formulation of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9388ab5266f95ff64f452ca71e49693
https://pubmed.ncbi.nlm.nih.gov/32352791

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Regulation, risk and safety of Faecal Microbiota Transplant

Autor: Debbie L. Shawcross, Liz Allen, Blair Merrick, Ben Forbes, Simon D. Goldenberg, Nur Masirah M. Zain

Publikováno v: Infection Prevention in Practice, Vol 2, Iss 3, Pp 100069-(2020)
Infection Prevention in Practice

Summary From its origins as a left-field, experimental, and even “maverick” intervention, faecal microbiota transplantation (FMT) is now a well-recognised, accepted, and potentially life-saving therapeutic strategy, for the management of recurren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e95639c9b5b8bc3b5f2057554bf66e
https://pubmed.ncbi.nlm.nih.gov/34316559

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ePS6.04 2-Alkyl-4-quinolone quorum sensing signal molecules are potential biomarkers in cystic fibrosis pseudomonal infection

Autor: Paul Williams, Douglas L Forrester, Nigel Halliday, Nur Masirah M. Zain, Andrew W. Fogarty, Alan J. Knox, Karmel Webb, Jane Dewar, David Honeybourne, Edward F. Nash, Helen L. Barr, David A. Barrett, Kenneth D. Bruce, Alan R. Smyth, Miguel Cámara, Joanna L. Whitehouse

Publikováno v: Journal of Cystic Fibrosis. 19:S53

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fde336d8acea227929d7559c5e0f8d2
https://doi.org/10.1016/s1569-1993(20)30332-5

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A Novel Microbiota Stratification System Predicts Future Exacerbations in Bronchiectasis

Autor: Nur Masirah M. Zain, Alice C.-H. Chen, David J. Serisier, Lucy D. Burr, Michael A. McGuckin, Geraint B. Rogers, Kenneth D. Bruce, Damian W. Rivett

Publikováno v: Annals of the American Thoracic Society. 11:496-503

Although airway microbiota composition correlates with clinical measures in non-cystic fibrosis bronchiectasis, these data are unlikely to provide useful prognostic information at the individual patient level. A system enabling microbiota data to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e746e89f2c6a17c9b5639bb62933e5f8
https://doi.org/10.1513/annalsats.201310-335oc

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