Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nur Jury"'
Autor:
Juan F. Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Paul B. Fallen, Shweta S. Puntambekar, Brad T. Casali, Nur Jury-Garfe, Pablo Martinez, Cristian A. Lasagna-Reeves, Gary E. Landreth
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114488- (2024)
Summary: Neuroinflammation is a prominent feature of Alzheimer’s disease (AD). Activated microglia undergo a reprogramming of cellular metabolism necessary to power their cellular activities during disease. Thus, selective targeting of microglial i
Externí odkaz:
https://doaj.org/article/2b24b58f479549e4a27d4bd15796989d
Autor:
Xavier Taylor, Pablo Cisternas, Nur Jury, Pablo Martinez, Xiaoqing Huang, Yanwen You, Javier Redding-Ochoa, Ruben Vidal, Jie Zhang, Juan Troncoso, Cristian A. Lasagna-Reeves
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Injured endothelial cells are shown to induce an A1 phenotype in astrocytes, characterized by a genetic signature associated with extracellular matrix remodeling factors (e.g. decorin and vascular Aß deposits).
Externí odkaz:
https://doaj.org/article/6e4bed3dd6d947798c173b0cc53b89e3
Autor:
Audrey Lee-Gosselin, Nur Jury-Garfe, Yanwen You, Luke Dabin, Disha Soni, Sayan Dutta, Jean-Christophe Rochet, Jungsu Kim, Adrian L. Oblak, Cristian A. Lasagna-Reeves
Publikováno v:
Cells, Vol 12, Iss 12, p 1597 (2023)
The role of TREM2 in Alzheimer’s disease (AD) is not fully understood. Previous studies investigating the effect of TREM2 deletion on tauopathy mouse models without the contribution of b-amyloid have focused only on tau overexpression models. Herei
Externí odkaz:
https://doaj.org/article/f8243020efa242c8bd809996117876e2
Autor:
Lasagna-Reeves, Audrey Lee-Gosselin, Nur Jury-Garfe, Yanwen You, Luke Dabin, Disha Soni, Sayan Dutta, Jean-Christophe Rochet, Jungsu Kim, Adrian L. Oblak, Cristian A.
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1597
The role of TREM2 in Alzheimer’s disease (AD) is not fully understood. Previous studies investigating the effect of TREM2 deletion on tauopathy mouse models without the contribution of b-amyloid have focused only on tau overexpression models. Herei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0c5195162f545648577cd8056cfc5077
Autor:
Pablo Martínez, Henika Patel, Yanwen You, Nur Jury Garfe, Abigail Perkins, Yingjian You, Xiaoqing Huang, Sayan Dutta, Aruna Wijeratne, Javier Redding, Amber L. Mosley, Chris Rochet, Jie Zhang, Juan C Troncoso, Cristian A Lasagna Reeves
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf92e8cd3092288458d81135511208d6
https://doi.org/10.1002/alz.060216
https://doi.org/10.1002/alz.060216
Autor:
Pablo Martinez, Henika Patel, Yanwen You, Nur Jury, Abigail Perkins, Audrey Lee-Gosselin, Xavier Taylor, Yingjian You, Gonzalo Viana Di Prisco, Xiaoqing Huang, Sayan Dutta, Aruna B. Wijeratne, Javier Redding-Ochoa, Syed Salman Shahid, Juan F. Codocedo, Sehong Min, Gary E. Landreth, Amber L. Mosley, Yu-Chien Wu, David L. McKinzie, Jean-Christophe Rochet, Jie Zhang, Brady K. Atwood, Juan Troncoso, Cristian A. Lasagna-Reeves
Publikováno v:
Nature neuroscience. 25(12)
Tau aggregation is a defining histopathological feature of Alzheimer’s disease and other tauopathies. However, the cellular mechanisms involved in tau propagation remain unclear. Here, we performed an unbiased quantitative proteomic study to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ab07adc7639f434e9c31dd767023b0
https://pubmed.ncbi.nlm.nih.gov/36344699
https://pubmed.ncbi.nlm.nih.gov/36344699
Autor:
Esteban Quezada, Martin Montecino, Claudio Cappelli, Nur Jury, Brigitte van Zundert, Iván Diaz, Robert H. Brown, Nicholas Wightman
Publikováno v:
Clinical Epigenetics
Background An intronic GGGGCC (G4C2) hexanucleotide repeat expansion (HRE) in the C9ORF72 gene is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), referred to as C9ALS/FTD. No cure or effective treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5348aa2add766d146afb25780ce318
https://pubmed.ncbi.nlm.nih.gov/33726839
https://pubmed.ncbi.nlm.nih.gov/33726839
Autor:
Cristian Arredondo, Carolina Cefaliello, Agnieszka Dyrda, Nur Jury, Pablo Martinez, Iván Díaz, Armando Amaro, Helene Tran, Danna Morales, Maria Pertusa, Lorelei Stoica, Elsa Fritz, Daniela Corvalán, Sebastián Abarzúa, Maxs Méndez-Ruette, Paola Fernández, Fabiola Rojas, Meenakshi Sundaram Kumar, Rodrigo Aguilar, Sandra Almeida, Alexandra Weiss, Fernando J. Bustos, Fernando González-Nilo, Carolina Otero, Maria Florencia Tevy, Daryl A. Bosco, Juan C. Sáez, Thilo Kähne, Fen-Biao Gao, James D. Berry, Katharine Nicholson, Miguel Sena-Esteves, Rodolfo Madrid, Diego Varela, Martin Montecino, Robert H. Brown, Brigitte van Zundert
Publikováno v:
Neuron. 110:1656-1670.e12
Non-cell-autonomous mechanisms contribute to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), in which astrocytes release unidentified factors that are toxic to motoneurons (MNs). We report her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0008063d400e3b00a4aa9c2dc5dafab6
https://doi.org/10.1016/j.neuron.2022.02.010
https://doi.org/10.1016/j.neuron.2022.02.010
Autor:
Jorge Toledo, Miguel V. Guerra, Estibaliz Ampuero, Jimmy Stehberg, Lorena Varela-Nallar, Rachael L. Neve, Steffen Härtel, Rodrigo Aguilar, Fahimeh Falahi, Fernando J. Bustos, Berta Henriquez, Marco Fuenzalida, Nur Jury, Ursula Wyneken, Miguel Sena-Esteves, Nibaldo C. Inestrosa, Martin Montecino, Brigitte van Zundert, Juan Ahumada, Paula Cubillos, Jaclyn Lata, Marianne G. Rots
Publikováno v:
Brain
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Brain, 140, 3252-3268. Oxford University Press
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Brain, 140, 3252-3268. Oxford University Press
The Dlg4 gene encodes for post-synaptic density protein 95 (PSD95), a major synaptic protein that clusters glutamate receptors and is critical for plasticity. PSD95 levels are diminished in ageing and neurodegenerative disorders, including Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fcf35288aa530f463ca33aae315838f
https://doi.org/10.1093/brain/awx272
https://doi.org/10.1093/brain/awx272
Autor:
Magdalena Sanhueza, Karen Jaramillo, Maria Florencia Tevy, Julia Kzhyshkowska, Brigitte van Zundert, Muriel D. Mardones, Sebastian Abarzua, Matias Campos, Susanne Ibing, Rachael L. Neve, Fernando J. Bustos, Henny Haensgen, Nur Jury, Estibaliz Ampuero, Lorena Varela-Nallar, Pablo Martinez, Martin Montecino
Publikováno v:
Journal of Cellular Physiology
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
J Cell Physiol
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
J Cell Physiol
Dendrite arbor growth, or dendritogenesis, is choreographed by a diverse set of cues, including the NMDA receptor (NMDAR) subunits NR2A and NR2B. While NR1NR2B receptors are predominantly expressed in immature neurons and promote plasticity, NR1NR2A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba9e33b4716246d90cd958ee70b2aad
https://doi.org/10.1002/jcp.25843
https://doi.org/10.1002/jcp.25843