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Formal syntheses of lasubine II and subcosine II have been completed by the synthesis of epi-lasubine II. The synthesis involves diastereoselective allylation of a methoxy isoxazolidine and a tandem hydrogenation process leading stereoselectively to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de7adacaf9f67d5a3802d0f9cdedb67
https://hdl.handle.net/10356/83262
https://hdl.handle.net/10356/83262
Publikováno v:
Tetrahedron. 70:2134-2140
A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hyd