Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Nunzia Matrone"'
Autor:
Pietro Paolo Vitiello, Giulia Martini, Luigi Mele, Emilio Francesco Giunta, Vincenzo De Falco, Davide Ciardiello, Valentina Belli, Claudia Cardone, Nunzia Matrone, Luca Poliero, Virginia Tirino, Stefania Napolitano, Carminia Della Corte, Francesco Selvaggi, Gianpaolo Papaccio, Teresa Troiani, Floriana Morgillo, Vincenzo Desiderio, Fortunato Ciardiello, Erika Martinelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Abstract Background Despite the advancements in new therapies for colorectal cancer (CRC), chemotherapy still constitutes the mainstay of the medical treatment. For this reason, new strategies to increase the efficacy of chemotherapy are desirable. P
Externí odkaz:
https://doaj.org/article/ee6656f7232f43be80a2f6cd65a8083d
Autor:
Valentina Belli, Nunzia Matrone, Stefania Napolitano, Giorgia Migliardi, Francesca Cottino, Andrea Bertotti, Livio Trusolino, Erika Martinelli, Floriana Morgillo, Davide Ciardiello, Vincenzo De Falco, Emilio Francesco Giunta, Umberto Bracale, Fortunato Ciardiello, Teresa Troiani
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Targeting the epidermal growth factor receptor (EGFR) either alone or in combination with chemotherapy is an effective treatment for patients with RAS wild-type metastatic colorectal cancer (mCRC). However, only a small percentage
Externí odkaz:
https://doaj.org/article/2140b1307dbb4f399e9a47c0af881d05
Autor:
Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini, Davide Ciardiello, Valentina Belli, Nunzia Matrone, Giusi Barra, Stefania Napolitano, Carmina Della Corte, Mimmo Turano, Maria Furia, Teresa Troiani, Floriana Morgillo, Ferdinando De Vita, Fortunato Ciardiello, Erika Martinelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Background Previous studies showed that the combination of an anti-Epidermal growth factor (EGFR) and a MEK-inhibitor is able to prevent the onset of resistance to anti-EGFR monoclonal antibodies in KRAS-wild type colorectal cancer (CRC), wh
Externí odkaz:
https://doaj.org/article/3b8d8aeebd9d4986b83b180e5cba35b4
Autor:
Alberto Angrisani, Nunzia Matrone, Valentina Belli, Rosario Vicidomini, Nunzia Di Maio, Mimmo Turano, Filippo Scialò, Paolo Antonio Netti, Antonio Porcellini, Maria Furia
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 557-565 (2018)
The human DKC1 gene encodes dyskerin, an evolutionarily conserved nuclear protein whose overexpression represents a common trait of many types of aggressive sporadic cancers. As a crucial component of the nuclear H/ACA snoRNP complexes, dyskerin is i
Externí odkaz:
https://doaj.org/article/b6b394d1881f435cad3630f3b4141ba9
Autor:
Rosita Russo, Nunzia Matrone, Valentina Belli, Davide Ciardiello, Mariangela Valletta, Sabrina Esposito, Paolo Vincenzo Pedone, Fortunato Ciardiello, Teresa Troiani, Angela Chambery
Publikováno v:
Cancers, Vol 11, Iss 10, p 1430 (2019)
Background: The clinical impact of the monoclonal antibody cetuximab targeting the EGFR in colorectal cancer (CRC) is widely recognized. Nevertheless, the onset of cetuximab resistance is a serious issue that limits the effectiveness of this drug in
Externí odkaz:
https://doaj.org/article/3918a4d74a7f4c75b5ee2aa2a0d19874
Autor:
Erika Martinelli, Fortunato Ciardiello, Maria Sibilia, Giuseppe Signoriello, Daniele Rizzi, Tiziana Pia Latiano, Evaristo Maiello, Virginia Tirino, Anna Maria Rachiglio, Nicola Normanno, Veronica Moreno-Viedma, Mariel C. Paul, Vincenzo Desiderio, Gianpaolo Papaccio, Vincenzo Sforza, Nunzia Matrone, Floriana Morgillo, Carminia Maria Della Corte, Davide Ciardiello, Teresa Troiani, Stefania Napolitano, Valentina Belli, Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini
Supplementary Table 3: EPHA2 expression in tumor samples with HSCORE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a802b8696d8d52597033a5f36158547e
https://doi.org/10.1158/1535-7163.22505419
https://doi.org/10.1158/1535-7163.22505419
Autor:
Erika Martinelli, Fortunato Ciardiello, Maria Sibilia, Giuseppe Signoriello, Daniele Rizzi, Tiziana Pia Latiano, Evaristo Maiello, Virginia Tirino, Anna Maria Rachiglio, Nicola Normanno, Veronica Moreno-Viedma, Mariel C. Paul, Vincenzo Desiderio, Gianpaolo Papaccio, Vincenzo Sforza, Nunzia Matrone, Floriana Morgillo, Carminia Maria Della Corte, Davide Ciardiello, Teresa Troiani, Stefania Napolitano, Valentina Belli, Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini
The EPHA2 tyrosine kinase receptor is implicated in tumor progression and targeted therapies resistance. We evaluated EPHA2 as a potential resistance marker to the antiepidermal growth factor receptor (EGFR) monoclonal antibody cetuximab in colorecta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3509ddb3be89e10174f92b4e206491f8
https://doi.org/10.1158/1535-7163.c.6538054.v1
https://doi.org/10.1158/1535-7163.c.6538054.v1
Autor:
Erika Martinelli, Fortunato Ciardiello, Maria Sibilia, Giuseppe Signoriello, Daniele Rizzi, Tiziana Pia Latiano, Evaristo Maiello, Virginia Tirino, Anna Maria Rachiglio, Nicola Normanno, Veronica Moreno-Viedma, Mariel C. Paul, Vincenzo Desiderio, Gianpaolo Papaccio, Vincenzo Sforza, Nunzia Matrone, Floriana Morgillo, Carminia Maria Della Corte, Davide Ciardiello, Teresa Troiani, Stefania Napolitano, Valentina Belli, Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini
Supplementary Figure 1. A: Phosphoarray analysis of SW48 and SW48-CR cell lines. B: Silencing of EPHA2 decreases the sensitivity to ALW-II-41-27 in HCT15 and SW48-CR cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1aa7d65ce451b776aca9ce8d725ae9
https://doi.org/10.1158/1535-7163.22505434
https://doi.org/10.1158/1535-7163.22505434
Autor:
Erika Martinelli, Fortunato Ciardiello, Maria Sibilia, Giuseppe Signoriello, Daniele Rizzi, Tiziana Pia Latiano, Evaristo Maiello, Virginia Tirino, Anna Maria Rachiglio, Nicola Normanno, Veronica Moreno-Viedma, Mariel C. Paul, Vincenzo Desiderio, Gianpaolo Papaccio, Vincenzo Sforza, Nunzia Matrone, Floriana Morgillo, Carminia Maria Della Corte, Davide Ciardiello, Teresa Troiani, Stefania Napolitano, Valentina Belli, Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini
Supplementary Figure 2. A-B: Synergistic anti-proliferative effects of the combination of ALW-II-41-27 and cetuximab.C: Effect of Epha2 gene knockdown on cetuximab sensitivity in HCT116 and LOVO cell lines. D: Effects of combination treatment with AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bbec25c0d69783ceddb14d75972c30
https://doi.org/10.1158/1535-7163.22505431
https://doi.org/10.1158/1535-7163.22505431
Autor:
Erika Martinelli, Fortunato Ciardiello, Maria Sibilia, Giuseppe Signoriello, Daniele Rizzi, Tiziana Pia Latiano, Evaristo Maiello, Virginia Tirino, Anna Maria Rachiglio, Nicola Normanno, Veronica Moreno-Viedma, Mariel C. Paul, Vincenzo Desiderio, Gianpaolo Papaccio, Vincenzo Sforza, Nunzia Matrone, Floriana Morgillo, Carminia Maria Della Corte, Davide Ciardiello, Teresa Troiani, Stefania Napolitano, Valentina Belli, Pietro Paolo Vitiello, Claudia Cardone, Giulia Martini
Supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b56df6b0f698844e04b291aa6538b1
https://doi.org/10.1158/1535-7163.22505428.v1
https://doi.org/10.1158/1535-7163.22505428.v1