Výsledky vyhledávání - "Nunzia Amatruda"

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment

Autor: Nunzia Amatruda, Raoul A. Droeser, Silvio Däster, Carmela Fimognari, Valentina Mele, Giandomenica Iezzi, Robert Ivanek, Eleonora Turrini, Diego Calabrese, Giulio C. Spagnoli, Manuele G. Muraro, Paul Zajac

Publikováno v: Oncotarget

// Silvio Daster 1, * , Nunzia Amatruda 1, 2, * , Diego Calabrese 2 , Robert Ivanek 2 , Eleonora Turrini 3 , Raoul A. Droeser 1 , Paul Zajac 1, 2 , Carmela Fimognari 3 , Giulio C. Spagnoli 1, 2 , Giandomenica Iezzi 1, 2 , Valentina Mele 1, 2, ** , Ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748820b8a926baece9f490f202ef9559
https://doi.org/10.18632/oncotarget.13857

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Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-ß

Autor: Daniel Oertli, Chiara Bocelli-Tyndall, Francesca Amicarella, Diego Calabrese, Valentina Mele, Dennis Pfaff, Manuele G. Muraro, Thérèse J. Resink, Brynn Kvinlaug, Giandomenica Iezzi, Luigi Terracciano, Michael Heberer, Giulio C. Spagnoli, Ivan Martin, Nunzia Amatruda

Publikováno v: International journal of cancer. Journal international du cancer
International Journal of Cancer. Journal International du Cancer

Mesenchymal stem/stromal cells (MSC) are multipotent precursors endowed with the ability to home to primary and metastatic tumor sites, where they can integrate into the tumor-associated stroma. However, molecular mechanisms and outcome of their inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ec9c5ce9005198c6700048f9c2da3c

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Abstract 2029: Insight of 3D multicellular tumor spheroids for innovative culture models of potential relevance for the screening of anti-CRC compounds

Autor: Silvio Däster, Giandomenica Iezzi, Paul Zajac, Nunzia Amatruda, Giulio C. Spagnoli, Valentina Mele, Manuele G. Muraro, Diego Calabrese

Publikováno v: Cancer Research. 74:2029-2029

OBJECTIVE - Multicellular tumor spheroid is a well-known method for 3D in-vitro culture that better represent in-vivo condition. We exploited this system to culture human established colorectal cell lines to investigate how the presence or absence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1d14b60107401d9f68075d7792a98ac
https://doi.org/10.1158/1538-7445.am2014-2029

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Abstract 3834: Establishment and characterization of 3D multicellular tumor spheroids as preclinical in vitro models of human colorectal cancer

Autor: Silvio Daester, Valentina Mele, Paul Zajac, Nunzia Amatruda, Giandomenica Iezzi, Giulio C. Spagnoli, Diego Calabrese, Manuele G. Muraro

Publikováno v: Cancer Research. 73:3834-3834

Objective: Multicellular tumor spheroid is a well-known method for three-dimensional in-vitro culture that better represent in-vivo condition. We exploited this system to culture human established colorectal cell lines to investigate how the presence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::248bbf5075a03dfe264ca9c8b50fde44
https://doi.org/10.1158/1538-7445.am2013-3834

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Abstract 1476: Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β

Autor: Giandomenica Iezzi, Valentina Mele, Dennis Pfaff, Brynn T. Kvinlaug, Ivan Martin, Nunzia Amatruda, Chiara Bocelli-Tyndall, Luigi Terracciano, Francesca Amicarella, Thérèse J. Resink, Giulio C. Spagnoli, Manuele G. Muraro, Diego Calabrese

Publikováno v: Cancer Research. 73:1476-1476

Mesenchymal stem/stromal cells (MSC) are multipotent precursors endowed with the ability to home to primary and metastatic tumor site. Because of this feature, they are currently being used in preclinical models and in clinical trials as potential ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::778c48796eebbe82f5f01e40486b24dd
https://doi.org/10.1158/1538-7445.am2013-1476

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Abstract 1491: Tumor-associated stromal cells increase malignancy of human colorectal cancers through epithelial-to-mesenchymal transition

Autor: Luigi Terracciano, Markus Zuber, Valentina Mele, Giandomenica Iezzi, Nunzia Amatruda, Manuele G. Muraro, Ivan Martin, Giulio C. Spagnoli, Diego Calabrese, Chiara Bocelli-Tyndall, Francesca Amicarella

Publikováno v: Cancer Research. 72:1491-1491

BACKGROUNDS & AIMS: Exogenously administered mesenchymal stromal cells (MSCs) have been shown to migrate into tumor tissues and contribute to tumor development. Still unclear is however, whether MSCs are actually a component of the stroma associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72b1b93a82c8881e67497ba97cc9f0e8
https://doi.org/10.1158/1538-7445.am2012-1491

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