Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Nuno G. Oliveira"'
Autor:
Rita B. Soares, Rita Manguinhas, João G. Costa, Nuno Saraiva, Nuno Gil, Rafael Rosell, Sérgio P. Camões, Ines Batinic-Haberle, Ivan Spasojevic, Matilde Castro, Joana P. Miranda, Filipa Amaro, Joana Pinto, Ana S. Fernandes, Paula Guedes de Pinho, Nuno G. Oliveira
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2198 (2022)
The manganese(III) porphyrin MnTnHex-2-PyP5+ (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has been studied in the context of different human disease models, including cancer. Nevertheless
Externí odkaz:
https://doaj.org/article/67a72876692d4ab0aff01917ce527f4b
Autor:
Ana Flórido, Nuno Saraiva, Sara Cerqueira, Nuno Almeida, Maddy Parsons, Ines Batinic-Haberle, Joana P. Miranda, João G. Costa, Guia Carrara, Matilde Castro, Nuno G. Oliveira, Ana S. Fernandes
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 367-378 (2019)
Manganese(III) porphyrins (MnPs) are superoxide dismutase (SOD) mimics with demonstrated beneficial effects in cancer treatment in combination with chemo- and radiotherapy regimens. Despite the ongoing clinical trials, little is known about the effec
Externí odkaz:
https://doaj.org/article/2187bc21422b4a2db5e3ceee7004d36e
Autor:
Ana S. Serras, Joana S. Rodrigues, Madalena Cipriano, Armanda V. Rodrigues, Nuno G. Oliveira, Joana P. Miranda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The poor predictability of human liver toxicity is still causing high attrition rates of drug candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing authorization stages. This is in part caused by animal models th
Externí odkaz:
https://doaj.org/article/5c2ae96c668549b1be074ca02a296405
Autor:
Javier Egea, Isabel Fabregat, Yves M. Frapart, Pietro Ghezzi, Agnes Görlach, Thomas Kietzmann, Kateryna Kubaichuk, Ulla G. Knaus, Manuela G. Lopez, Gloria Olaso-Gonzalez, Andreas Petry, Rainer Schulz, Jose Vina, Paul Winyard, Kahina Abbas, Opeyemi S. Ademowo, Catarina B. Afonso, Ioanna Andreadou, Haike Antelmann, Fernando Antunes, Mutay Aslan, Markus M. Bachschmid, Rui M. Barbosa, Vsevolod Belousov, Carsten Berndt, David Bernlohr, Esther Bertrán, Alberto Bindoli, Serge P. Bottari, Paula M. Brito, Guia Carrara, Ana I. Casas, Afroditi Chatzi, Niki Chondrogianni, Marcus Conrad, Marcus S. Cooke, João G. Costa, Antonio Cuadrado, Pham My-Chan Dang, Barbara De Smet, Bilge Debelec–Butuner, Irundika H.K. Dias, Joe Dan Dunn, Amanda J. Edson, Mariam El Assar, Jamel El-Benna, Péter Ferdinandy, Ana S. Fernandes, Kari E. Fladmark, Ulrich Förstermann, Rashid Giniatullin, Zoltán Giricz, Anikó Görbe, Helen Griffiths, Vaclav Hampl, Alina Hanf, Jan Herget, Pablo Hernansanz-Agustín, Melanie Hillion, Jingjing Huang, Serap Ilikay, Pidder Jansen-Dürr, Vincent Jaquet, Jaap A. Joles, Balaraman Kalyanaraman, Danylo Kaminskyy, Mahsa Karbaschi, Marina Kleanthous, Lars-Oliver Klotz, Bato Korac, Kemal Sami Korkmaz, Rafal Koziel, Damir Kračun, Karl-Heinz Krause, Vladimír Křen, Thomas Krieg, João Laranjinha, Antigone Lazou, Huige Li, Antonio Martínez-Ruiz, Reiko Matsui, Gethin J. McBean, Stuart P. Meredith, Joris Messens, Verónica Miguel, Yuliya Mikhed, Irina Milisav, Lidija Milković, Antonio Miranda-Vizuete, Miloš Mojović, María Monsalve, Pierre-Alexis Mouthuy, John Mulvey, Thomas Münzel, Vladimir Muzykantov, Isabel T.N. Nguyen, Matthias Oelze, Nuno G. Oliveira, Carlos M. Palmeira, Nikoletta Papaevgeniou, Aleksandra Pavićević, Brandán Pedre, Fabienne Peyrot, Marios Phylactides, Gratiela G. Pircalabioru, Andrew R. Pitt, Henrik E. Poulsen, Ignacio Prieto, Maria Pia Rigobello, Natalia Robledinos-Antón, Leocadio Rodríguez-Mañas, Anabela P. Rolo, Francis Rousset, Tatjana Ruskovska, Nuno Saraiva, Shlomo Sasson, Katrin Schröder, Khrystyna Semen, Tamara Seredenina, Anastasia Shakirzyanova, Geoffrey L. Smith, Thierry Soldati, Bebiana C. Sousa, Corinne M. Spickett, Ana Stancic, Marie José Stasia, Holger Steinbrenner, Višnja Stepanić, Sebastian Steven, Kostas Tokatlidis, Erkan Tuncay, Belma Turan, Fulvio Ursini, Jan Vacek, Olga Vajnerova, Kateřina Valentová, Frank Van Breusegem, Lokman Varisli, Elizabeth A. Veal, A. Suha Yalçın, Olha Yelisyeyeva, Neven Žarković, Martina Zatloukalová, Jacek Zielonka, Rhian M. Touyz, Andreas Papapetropoulos, Tilman Grune, Santiago Lamas, Harald H.H.W. Schmidt, Fabio Di Lisa, Andreas Daiber
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 94-162 (2017)
The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated t
Externí odkaz:
https://doaj.org/article/637c0e34ca5240b4924d5b20463b39fc
Autor:
Rita Manguinhas, Ana S. Fernandes, João G. Costa, Nuno Saraiva, Sérgio P. Camões, Nuno Gil, Rafael Rosell, Matilde Castro, Joana P. Miranda, Nuno G. Oliveira
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 550 (2020)
Elevated expression levels of the apurinic/apyrimidinic endonuclease 1 (APE1) have been correlated with the more aggressive phenotypes and poor prognosis of non-small cell lung cancer (NSCLC). This study aimed to assess the impact of the inhibition o
Externí odkaz:
https://doaj.org/article/46f20bc6e47f419a90aa09ab839afbab
Autor:
Nuno Torres, Sandrina Gonçalves, Ana S. Fernandes, J. Franco Machado, Maria J. Villa de Brito, Nuno G. Oliveira, Matilde Castro, Judite Costa, Maria F. Cabral
Publikováno v:
Molecules, Vol 19, Iss 1, Pp 550-567 (2014)
The purpose of this work was to synthesize and characterize the thiatetraaza macrocycle 1-thia-4,7,10,13-tetraazacyclopentadecane ([15]aneN4S). Its acid-base behaviour was studied by potentiometry at 25 °C and ionic strength 0.10 M in KNO3. The prot
Externí odkaz:
https://doaj.org/article/992cc1b9ab644357a50ed48c31da2fd8
Autor:
João G. Costa, Nuno Saraiva, Ines Batinic-Haberle, Matilde Castro, Nuno G. Oliveira, Ana S. Fernandes
Publikováno v:
Antioxidants, Vol 8, Iss 10, p 490 (2019)
Clear-cell renal carcinoma (ccRCC) is the most common type of renal cancer. The importance of oxidative stress in the context of this disease has been described, although there is only little information concerning the role of superoxide dismutase (S
Externí odkaz:
https://doaj.org/article/dfffa1ff28b040a7834903b3bdd9e947
Autor:
Inês L. Martins, Joana P. Miranda, Nuno G. Oliveira, Ana S. Fernandes, Sandrina Gonçalves, Alexandra M. M. Antunes
Publikováno v:
Molecules, Vol 18, Iss 5, Pp 5251-5264 (2013)
We report the development of a new microwave-based synthetic methodology mediated by Woollins’ reagent that allowed an efficient conversion of caffeine into 6-selenocaffeine. A preliminary evaluation on the modulation of antioxidant activity upon s
Externí odkaz:
https://doaj.org/article/3a0474ceb2c145adb39a74421f51e0f5
Publikováno v:
Psychoactives. 1:64-69
Exposure to psychoactive substances is undoubtedly a serious public health issue that should be carefully analyzed from different perspectives. Regarding the types of toxic effects inflicted by these xenobiotics, it is already known that many of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8162465cc50c7bb73601e7c7efc9de69
https://doi.org/10.3390/psychoactives1020007
https://doi.org/10.3390/psychoactives1020007
Autor:
Rita B, Soares, Rita, Manguinhas, João G, Costa, Nuno, Saraiva, Nuno, Gil, Rafael, Rosell, Sérgio P, Camões, Ines, Batinic-Haberle, Ivan, Spasojevic, Matilde, Castro, Joana P, Miranda, Filipa, Amaro, Joana, Pinto, Ana S, Fernandes, Paula, Guedes de Pinho, Nuno G, Oliveira
Publikováno v:
Antioxidants (Basel, Switzerland). 11(11)
The manganese(III) porphyrin MnTnHex-2-PyP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d167f3b6f2d2e6d09c95545202710515
https://pubmed.ncbi.nlm.nih.gov/36358570
https://pubmed.ncbi.nlm.nih.gov/36358570