Výsledky vyhledávání - "Nuno E. Silva"

A Single Dose of Marine Chlorella vulgaris Increases Plasma Concentrations of Lutein, β-Carotene and Zeaxanthin in Healthy Male Volunteers

Autor: Gonçalo Real, Ana Teresa Serra, Ana Maria Carvalho Partidário, Ana Bárbara Pereira, Agostinho Manuel dos Reis Carrondo Alexandre Alexandre, Torsten Bohn, Sandra D. Silva, Carolina V. Pereira, V.S.S. Gonçalves, Maria Rosário Bronze, Pedro Escudero, Nuno E. Silva, Luis Pleno de Gouveia, Naiara Fernández, Ana Matias

Publikováno v: Antioxidants, Vol 10, Iss 1164, p 1164 (2021)
Antioxidants

The beneficial health effects of Chlorella vulgaris have been associated with the presence of several nutrients and antioxidants, including carotenoids. However, the in vivo bioavailability of Chlorella is still poorly evaluated. In this work, a huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2640901cece79b34edb0679fbb48d72c
https://www.mdpi.com/2076-3921/10/8/1164

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Artificial neural networks applied to quality-by-design: From formulation development to clinical outcome

Autor: Nuno E. Silva, Gabriel Leitao Silva, Marta F. Simões, Rui M. A. Pinto, Ana Catarina Pinto, Sérgio Simões, Marlene Fonseca

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 152

Quality-by-Design (QbD) is a methodology used to build quality into products and is characterized by a well-defined roadmap. In this study, the application of Artificial Neural Networks (ANNs) in the QbD-based development of a test drug product is pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83e3e8a6c27b9aef63e09ddaa0121e5
https://pubmed.ncbi.nlm.nih.gov/32442736

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Physiologically-Based Pharmacokinetic Model on the Oral Drug Absorption in Roux-en-Y Gastric Bypass Bariatric Patients: Amoxicillin Tablet and Suspension

Autor: Andréa Diniz, Maiara Camotti Montanha, Nuno E. Silva, Elza Kimura, Paulo Paixão

Publikováno v: Molecular pharmaceutics. 16(12)

The potential of a physiologically-based pharmacokinetic (PBPK) model to predict oral amoxicillin bioavailability, by considering the physiological changes after "Roux-en-Y gastric bypass" (RYGB) surgery in bariatric patients, was evaluated. A middle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f48e42dd33ad36592d85852eac0e26c
https://pubmed.ncbi.nlm.nih.gov/31721592

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Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients

Autor: Catarina Pinho, João Gonçalves-Pereira, Pedro Póvoa, Nuno E. Silva, André Mateus

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
BMC Pharmacology & Toxicology

Background: Meropenem is a carbapenem antibiotic commonly used in critically ill patients to treat severe infections. The available pharmacokinetic (PK) data has been mostly obtained from healthy volunteers as well as from clinical studies addressing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55767650d9273bca0d41f69718e706b4
https://hdl.handle.net/10362/23248

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Bioequivalence evaluation of three different oral formulations of ciprofloxacin in healthy volunteers

Autor: Nuno E. Silva, Augusto E. P. Filipe, Manuela T. Maya, Nuno J. Goncalves, José A. Morais

Publikováno v: Scopus-Elsevier
CIÊNCIAVITAE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Two bioequivalence studies were performed in twenty four healthy male volunteers with the objective of comparing the bioavailability of three different oral formulations of ciprofloxacin as immediate release tablets 250, 500 and 750 mg (test formulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f7ffd5ef3e882b6853650d2d1a869c
https://hdl.handle.net/10451/21281

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Comparative Bioavailability of two immediate release tablets of enalapril/hydrochlorothiazide in healthy volunteers

Autor: Maria Cruz Caturla, Nuno E. Silva, José A. Morais, Augusto E. P. Filipe, M. Rovira, Manuela T. Maya, Nuno J. Goncalves

Publikováno v: Scopus-Elsevier
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

A bioequivalence study of two oral formulations of 20/12.5 mg tablets of enalaptil/hydrochlorothiazide was carried out in 20 healthy male volunteers according to a single dose, two-sequence, crossover randomized design. One washout period of nine day

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffac9f23dad19771b58ef158ff98c4a5
https://hdl.handle.net/10451/21280

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Relatório final de estágio: Escola EB. 1,2,3 Martim de Freitas Coimbra

Autor: Nunes, Ricardo Miguel de Martins

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Relatório de estágio do mestrado em Ensino da Educação Física nos Ensinos Básico e Secundário, apresentado à Fac. de Ciências do Desporto e Educação Fisica da Univ. de Coimbra Com a elaboração deste relatório final pretendeu-se realizar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::be7b839b8aa26aa02eb04d7c613543a1

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