Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nujoud Al‑Yousef"'
Autor:
Nisreen Al-Moghrabi, Maram Al-Showimi, Nujoud Al-Yousef, Bushra Al-Shahrani, Bedri Karakas, Lamyaa Alghofaili, Hannah Almubarak, Safia Madkhali, Hind Al Humaidan
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmiss
Externí odkaz:
https://doaj.org/article/a57d9ef0f1f549208a545219425bb2de
Autor:
Huda H Al-Khalaf, Dilek Colak, Maher Al-Saif, Albandary Al-Bakheet, Siti-Faujiah Hendrayani, Nujoud Al-Yousef, Namik Kaya, Khalid S Khabar, Abdelilah Aboussekhra
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21111 (2011)
BackgroundThe cyclin-D/CDK4,6/p16(INK4a)/pRB/E2F pathway, a key regulator of the critical G1 to S phase transition of the cell cycle, is universally disrupted in human cancer. However, the precise function of the different members of this pathway and
Externí odkaz:
https://doaj.org/article/d7f9ff83f9be405ab2aa0df2055b4300
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 9021
Constitutional BRCA1-methylation is a cancer risk factor for breast (BC) and ovarian (OC) cancer. MiR-155, regulated by BRCA1, is a multifunctional microRNA that plays a crucial role in the immune system. The present study assessed the modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3722e59130b38c0fc131f70c07325730
Autor:
Maram Al‑Showimi, Nujoud Al‑Yousef, Wejdan Alharbi, Sara Alkhezayem, Osama Almalik, Hamed Alhusaini, Amani Alghamdi, Nisreen Al‑Moghrabi
Publikováno v:
Oncology Letters. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d6c617c38d4336752559050528726c
https://doi.org/10.3892/ol.2022.13396
https://doi.org/10.3892/ol.2022.13396
Autor:
Safia Madkhali, Hannah Almubarak, Lamyaa Alghofaili, Maram Al-Showimi, Hind Al Humaidan, Nujoud Al-Yousef, Bushra Al-Shahrani, Nisreen Al-Moghrabi, Bedri Karakas
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Clinical Epigenetics
Clinical Epigenetics
Background Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmission of BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f81e35a0f648bc68a1faf969e2daa9f
http://link.springer.com/article/10.1186/s13148-018-0529-5
http://link.springer.com/article/10.1186/s13148-018-0529-5
Publikováno v:
Oncology Reports
Restoration of normal DNA promoter methylation and expression states of cancer-related genes may be an option for the prevention as well as the treatment of several types of cancer. Constitutional promoter methylation of BRCA1 DNA repair associated (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e49114bd1c529480cd459757c05e1eb
https://doi.org/10.3892/or.2020.7473
https://doi.org/10.3892/or.2020.7473
Publikováno v:
Journal of Clinical Epigenetics.
Background: Numerous microRNAs have been categorized as tumor suppressors that are often repressed by aberrant DNA methylation. Recently, BRCA1 promoter methylation in White Blood Cells (WBC) has been linked to elevated risk of developing breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17ca127db64c0cc9f8b8b7793b81091
https://doi.org/10.21767/2472-1158.100037
https://doi.org/10.21767/2472-1158.100037
Autor:
Nada Al-Tassan, Abdelilah Aboussekhra, Taher Al-Tweigeri, Abdelmoneim M. Eldali, Sooad K. Al-Daihan, Nujoud Al-Yousef, Abeer Al-Qasem, Mohamed Toulimat, Asma Tulbah
Publikováno v:
Oncology Letters. 2:363-369
Breast cancer remains a worldwide public health concern. The incidence and mortality of breast cancer varies significantly in ethnically and geographically distinct populations. In the Kingdom of Saudi Arabia (KSA) breast cancer has shown an increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26b9cd7798afa74774b3ff2b0583893
https://doi.org/10.3892/ol.2011.236
https://doi.org/10.3892/ol.2011.236
Publikováno v:
Nucleic Acids Research
p16INK4a and p21WAF1, two major cyclin-dependent kinase inhibitors, are the products of two tumor suppressor genes that play important roles in various cellular metabolic pathways. p21WAF1 is up-regulated in response to different DNA damaging agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce3591619aaab7d872b851aad611c1a
https://doi.org/10.1093/nar/gkl1075
https://doi.org/10.1093/nar/gkl1075
Autor:
Ibrahim Al-Jammaz, Abdelilah Aboussekhra, Nujoud Al-Yousef, Ameera Gaafar, Basem Al-Otaibi, Khaled Al-Hussein
Publikováno v:
Journal of ethnopharmacology. 143(3)
Ethnopharmacological relevance While camel urine (CU) is widely used in the Arabian Peninsula to treat various diseases, including cancer, its exact mechanism of action is still not defined. The objective of the present study is to investigate whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aebe439006d60601350cca98254df5f
https://pubmed.ncbi.nlm.nih.gov/22922085
https://pubmed.ncbi.nlm.nih.gov/22922085