Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nucleotide Exchange Factor SIL1"'
Autor:
Colin J. Stirling, Amy L. Black, K. Y. Benjamin Yeo, Kelsi Wells, Carl J. Mousley, Robert F. L. Steuart, Kofi L. P. Stevens, Benjamin L. Schulz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(47)
BiP (Kar2 in yeast) is an essential Hsp70 chaperone and master regulator of endoplasmic reticulum (ER) function. BiP's activity is regulated by its intrinsic ATPase activity that can be stimulated by two different nucleotide exchange factors, Sil1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45de2b4874522457d06da8be5f7c31fd
https://pubmed.ncbi.nlm.nih.gov/29109265
https://pubmed.ncbi.nlm.nih.gov/29109265
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Unfavorable redox conditions in the endoplasmic reticulum (ER) can decrease the capacity for protein secretion, altering vital cell functions. While systems to manage reductive stress are well-established, how cells cope with an overly oxidizing ER r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770c25240571494d9624011375d7bb17
https://elifesciences.org/articles/24141
https://elifesciences.org/articles/24141
Autor:
Janet van Eersel, Lars M. Ittner, Tse Yan Becky Chan, Josefine Bertz, Arne Ittner, Patsie Polly
Publikováno v:
Diabetologia. 57:1410-1419
Regulation of insulin secretion along the secretory pathway is incompletely understood. We addressed the expression of SIL1, a nucleotide exchange factor for the endoplasmic reticulum (ER) chaperone glucose-regulated protein 78 kD (GRP78), in pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a188d606e6e010a710c9c29af88e2f43
https://doi.org/10.1007/s00125-014-3230-z
https://doi.org/10.1007/s00125-014-3230-z
Publikováno v:
Science Progress. 103:003685041989104
Breast cancer, as one of the most malignant tumors, poses a serious threat to the lives of females. Nucleotide exchange factor SIL1 is an important regulator of endoplasmic reticulum function that might have a specific role in tumor progression. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47e6dff19fb4f2b92265e9d641cfdc8
https://doi.org/10.1177/0036850419891046
https://doi.org/10.1177/0036850419891046
Akademický článek
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Akademický článek
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Autor:
Perlman S; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California
Publikováno v:
1993.
Autor:
Anttonen AK; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Publikováno v:
1993.