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pro vyhledávání: '"Nucleic acid thermodynamics"'
Akademický článek
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Autor:
Paolo Rissone, Felix Ritort
Publikováno v:
Life, Vol 12, Iss 7, p 1089 (2022)
Force-spectroscopy techniques have led to significant progress in studying the physicochemical properties of biomolecules that are not accessible in bulk assays. The application of piconewton forces with laser optical tweezers to single nucleic acids
Externí odkaz:
https://doaj.org/article/2ff00a53af1943c7ad6a00f8dc2c70b4
Autor:
Katherine A. Willets, David J. Masiello, Abigail P. Crawford, Claire A. West, Gabe DeLong, Phillip A. Reinhardt, Stephan Link
Publikováno v:
The Journal of Physical Chemistry B. 125:12197-12205
Photothermal heating of nanoparticles has applications in nanomedicine, photocatalysis, photoelectrochemistry, and data storage, but accurate measurements of temperature at the nanoparticle surface are lacking. Here we demonstrate progress toward a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f512f563d44e28aa9657e1a5a5224a4
https://doi.org/10.1021/acs.jpcb.1c08348
https://doi.org/10.1021/acs.jpcb.1c08348
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:5337-5345
Genotyping of single nucleotide variants (SNVs) has enabled the assessment of disease-related risk factors and significantly improved the potency of diagnosis and prognosis. Meanwhile, genotyping of SNVs is challenging due to the high sequence simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cb6c774909383b322f6bd778d708c3
https://doi.org/10.1007/s00216-021-03708-7
https://doi.org/10.1007/s00216-021-03708-7
Publikováno v:
Analytical Chemistry. 93:13919-13927
The development of multifunctional nanoplatforms that integrate both diagnostic and therapeutic functions has always been extremely desirable and challenging in the cancer combat. Here, we report an endogenous miRNA-activated DNA nanomachine (EMDN) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3305a8ea79ff57fbc5c0f5df0a92a07
https://doi.org/10.1021/acs.analchem.1c02907
https://doi.org/10.1021/acs.analchem.1c02907
Publikováno v:
Analytical Chemistry. 93:8354-8361
Hybridization chain reaction (HCR) amplification strategy has been extensively explored for the application of electrochemical DNA-based sensors. Despite the enhancement in its sensitivity using the HCR, such sensor platform exhibited significant sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6114dd29f9cd24baa6786d3a81b670a
https://doi.org/10.1021/acs.analchem.1c01436
https://doi.org/10.1021/acs.analchem.1c01436
Autor:
Chunlei Jiao, Sahil Sharma, Lars Barquist, Yanying Yu, Oliver Kurzai, Christoph Schoen, Gaurav Dugar, Natalia L. Peeck, Franziska Wimmer, Cynthia M. Sharma, Thorsten Bischler, Chase L. Beisel
Publikováno v:
Science (New York, N.y.)
Cellular RNAs guide CRISPR-Cas9 The Cas9 nuclease widely used for genome editing is derived from natural bacterial defense systems that protect against invading viruses. Cas9 is directed by RNA guides to cut matching viral DNA. Jiao et al. discovered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0479d0730260a491d7b532522657ec7b
https://doi.org/10.1126/science.abe7106
https://doi.org/10.1126/science.abe7106
Autor:
Yasemin Yildizhan, Ying Xia, Zoë A. E. Waller, Rianne M. Lord, Ceyda Acilan, Baris Sergi, Ipek Bulut
Publikováno v:
ChemMedChem
Chemmedchem
Chemmedchem
To understand the potential in vitro modes of action of bis(β‐diketonato) oxovanadium(IV) complexes, nine compounds of varying functionality have been screened using a range of biological techniques. The antiproliferative activity against a range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74963f2bce68b9feb2b8c12f612412a0
https://doi.org/10.1002/cmdc.202100152
https://doi.org/10.1002/cmdc.202100152
Autor:
Richard A Schäfer, Björn Voß
Publikováno v:
Nucleic Acids Research
RNA–RNA inter- and intramolecular interactions are fundamental for numerous biological processes. While there are reasonable approaches to map RNA secondary structures genome-wide, understanding how different RNAs interact to carry out their regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c78beae3101232dc4d1d452f8b6f3a
https://doi.org/10.1093/nar/gkab340
https://doi.org/10.1093/nar/gkab340
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 991-1000 (2021)
Eleven novel 10-O-aryl-substituted berberrubine and berberine derivatives were synthesized by the Cu2+-catalyzed Chan–Evans–Lam coupling of berberrubine with arylboronic acids and subsequent 9-O-methylation. The reaction is likely introduced by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d20c917d16efc50daed9a16073b8dd
https://doaj.org/article/c6db9fdf6b664e009195e10f24d73ccf
https://doaj.org/article/c6db9fdf6b664e009195e10f24d73ccf