Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Nuclear signaling"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Sexual dimorphism exists in the epidemiology of cardiovascular disease (CVD), which indicates the involvement of sexual hormones in the pathophysiology of CVD. In particular, ample evidence has demonstrated estrogen's protective effect on the cardiov
Externí odkaz:
https://doaj.org/article/22c278a37dce4141811ca12a652540d3
Autor:
Ghannam, ElSayed Eid ElSayed
The overarching goal of this study is to conduct an investigation of regional perspectives on the impact of Israel's nuclear monopoly on nuclear decisions in the Middle East. This Dissertation addresses the question as to why regional actors have tak
Externí odkaz:
http://hdl.handle.net/10919/112755
Autor:
Kazutaka Ueda, Nobuaki Fukuma, Yusuke Adachi, Genri Numata, Hiroyuki Tokiwa, Masayuki Toyoda, Akira Otani, Masaki Hashimoto, Pang-Yen Liu, Eiki Takimoto
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Great progress has been made in the understanding of the pathophysiology of cardiovascular diseases (CVDs), and this has improved the prevention and prognosis of CVDs. However, while sex differences in CVDs have been well documented and studied for d
Externí odkaz:
https://doaj.org/article/b5699724fc734137a6f21c613ef39436
Autor:
Yu Sun, Yifan Lu, Jason Saredy, Xianwei Wang, Charles Drummer IV, Ying Shao, Fatma Saaoud, Keman Xu, Ming Liu, William Y. Yang, Xiaohua Jiang, Hong Wang, Xiaofeng Yang
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101696- (2020)
Reactive oxygen species (ROS) are critical for the progression of cardiovascular diseases, inflammations and tumors. However, the mechanisms of how ROS sense metabolic stress, regulate metabolic pathways and initiate proliferation, inflammation and c
Externí odkaz:
https://doaj.org/article/a5e8118a58074c5c8950df977a5b7fe1
Autor:
Crossin, Kathryn L., Tai, Ming-Hong, Krushel, Leslie A., Mauro, Vincent P., Edelman, Gerald M.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1997 Mar . 94(6), 2687-2692.
Externí odkaz:
https://www.jstor.org/stable/41700
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Mitochondria are cellular organelles that control metabolic homeostasis and ATP generation, but also play an important role in other processes, like cell death decisions and immune signaling. Mitochondria produce a diverse array of metabolites that a
Externí odkaz:
https://doaj.org/article/2c9b3e012d0b4f549084fa49b6c10821
Publikováno v:
Cells, Vol 10, Iss 7, p 1801 (2021)
Many anti-cancer therapeutics lead to the release of danger associated pattern molecules (DAMPs) as the result of killing large numbers of both normal and transformed cells as well as lysis of red blood cells (RBC) (hemolysis). Labile heme originatin
Externí odkaz:
https://doaj.org/article/3e9d74f60e3c47f4ba7fadf1f5fa920d
Autor:
Matthias R. Meyer, Matthias Barton
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • The role of ERα non-nuclear signaling in female heart failure was investigated, using a novel mouse line in which ERα non-nuclear signaling was selectively disrupted by inhibiting the interaction between ERα and
Highlights • The role of ERα non-nuclear signaling in female heart failure was investigated, using a novel mouse line in which ERα non-nuclear signaling was selectively disrupted by inhibiting the interaction between ERα and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b353abdb69e8f5cf341a6505d8e5ce74
http://europepmc.org/articles/PMC7091503
http://europepmc.org/articles/PMC7091503
Autor:
Natasha S. Clayton, Millie Fox, Jose J. Vicenté-Garcia, Courtney M. Schroeder, Trevor D. Littlewood, Jonathon I. Wilde, Kadalmani Krishnan, Murray J.B. Brown, Claire Crafter, Helen R. Mott, Darerca Owen
Activated Cdc42-associated kinase (ACK) is an oncogenic nonreceptor tyrosine kinase associated with poor prognosis in several human cancers. ACK promotes proliferation, in part by contributing to the activation of Akt, the major effector of class 1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41be413a469124b50749c5c7e055601e
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