Zobrazeno 1 - 10
of 10 354
pro vyhledávání: '"Nuclear factor-κB"'
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 16, Pp 340-347 (2024)
Objective: To investigate the effect and mechanism of Hippophae rhamnoides flavone (HRF) on polycystic ovarian syndrome (PCOS) in rats, and to provide new ideas for the prevention and treatment of PCOS. Methods: A PCOS rat model was duplicated by giv
Externí odkaz:
https://doaj.org/article/5f6eaec194a9434398d23e58bee4909a
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 4, Pp 489-495 (2024)
Objective To explore the therapeutic effect and mechanism of pachymic acid(PA) on Helicobacter pylori(Hp)-associated gastritis in rats. Methods A rat model of Hp-associated gastritis was established; all rats were separated into control group(CT grou
Externí odkaz:
https://doaj.org/article/b3c0928b34be40949c40b5bbd28960f9
Autor:
Jie Yuan, Bhanuprakash C. Narasimhachar, Akshay Ravish, Li Yang, Hua Zhang, Qun Wang, Zhi Li, Jun Huang, Bei Wang, Geng Wang, Keshav Kumar Harish, Arunachalam Chinnathambi, Chandramohan Govindasamy, Mahendra Madegowda, Basappa Basappa
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionNuclear factor kappa (NF-κB) plays a key role in cancer cell proliferation; thus, small molecule inhibitors of NF-κB activity can effectively inhibit breast cancer (BC) progression. We have previously reported oxazine and piperazine-lin
Externí odkaz:
https://doaj.org/article/66c2cc0a7bac4368a394f36398fd78cd
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34509- (2024)
Macrophages are important for maintaining tissue homeostasis and defending against pathogens in periodontal tissues. However, these tissues are often vulnerable to damage due to local inflammatory responses within the host tissues. This study aimed t
Externí odkaz:
https://doaj.org/article/55bf5a3571b4495da28a1c7cf259d1bb
Publikováno v:
Endocrine Journal, Vol 71, Iss 4, Pp 417-427 (2024)
Lipopolysaccharide (LPS) and Receptor Activator of Nuclear Factor-κB Ligand (RANKL) are the two important factors causing bone loss, which is an important pathogenesis for osteoporosis. However, the relationship between LPS and RANKL is not yet clea
Externí odkaz:
https://doaj.org/article/17dc99b2950a44d1b47acb7ba13b272d
Publikováno v:
Shipin Kexue, Vol 45, Iss 3, Pp 42-52 (2024)
Objective: To explore the repairing effect and underlying mechanism of fucoxanthin on non-alcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD) in C57BL/6 mice. Methods: Fifty-two C57BL/6 mice were randomly divided into four groups,
Externí odkaz:
https://doaj.org/article/483dcb3574574dd18be30e92188799bd
Autor:
Bo Zhang, Zechao Qu, Hua Hui, Baorong He, Dong Wang, Yong Zhang, Yiwei Zhao, Jingjun Zhang, Liang Yan
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-18 (2024)
Abstract Background Isoorientin (ISO) is a glycosylated flavonoid with antitumor, anti-inflammatory, and antioxidant properties. However, its effects on bone metabolism remain largely unknown. Methods In this study, we aimed to investigate the effect
Externí odkaz:
https://doaj.org/article/23da70e59f1a410cb7637a01a09cfed5
Autor:
Yu-Ze Zhao, Xue-Ning Zhang, Yi Yin, Pei-Lun Xiao, Meng Gao, Lu-Ming Zhang, Shuan-Hu Zhou, Shu-Na Yu, Xiao-Li Wang, Yan-Song Zhao
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 2, Pp 228-238 (2024)
AIM: To observe the effects of N-acetylserotonin (NAS) administration on retinal ischemia-reperfusion (RIR) injury in rats and explore the underlying mechanisms involving the high mobility group box 1 (HMGB1)/receptor for advanced glycation end-produ
Externí odkaz:
https://doaj.org/article/fc39ad5c34ba47bbbf8548d1a79714b2
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 10, Iss 1, Pp 33-39 (2024)
Objective: The objective of this study was to investigate the effects and possible mechanisms of action of ginseng on cerebral vasospasm and early brain injury (EBI) following hemorrhagic stroke. Materials and Methods: Sprague-Dawley (SD) rats (n = 4
Externí odkaz:
https://doaj.org/article/1ea9e48c6aa74896912fbde493895624
Autor:
Xianshe Meng, Shihong Zheng, Zequn Yin, Xuerui Wang, Daigang Yang, Tingfeng Zou, Huaxin Li, Yuanli Chen, Chenzhong Liao, Zhouling Xie, Xiaodong Fan, Jihong Han, Yajun Duan, Xiaoxiao Yang
Publikováno v:
Food Science and Human Wellness, Vol 13, Iss 1, Pp 211-224 (2024)
Psoriasis is a chronic autoimmune disease featured by patches on the skin. It is caused by malfunction of immune cells and keratinocytes with inflammation as one of its key features. Apigenin (API) is a natural flavonoid with anti-inflammatory and im
Externí odkaz:
https://doaj.org/article/6988ac0544fe4466a96a186760f1e7ce