Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nucharee Yokdang"'
Autor:
Catalina Simion, Mingyi Chen, Dennis Chang, Jason Hatakeyama, Jessica H. Wald, William J. Murphy, Manojit Mosur Swamynathan, Joseph Tellez, Kermit L. Carraway, Colleen A Sweeney, Nucharee Yokdang
Publikováno v:
Oncogene, vol 35, iss 22
Oncogene
Oncogene
LRIG1 (leucine-rich repeat and immunoglobulin-like domain containing), a member of the LRIG family of transmembrane leucine-rich repeat-containing proteins, is a negative regulator of receptor tyrosine kinase signaling and a tumor suppressor. LRIG1 e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61eb272705da658a63d06181ee1e92f
https://escholarship.org/uc/item/9v69m814
https://escholarship.org/uc/item/9v69m814
Autor:
Nucharee Yokdang, Iain L. O. Buxton
Publikováno v:
Cancers, Vol 3, Iss 3, Pp 2844-2857 (2011)
Cancers
Cancers
The notion that breast cancers can survive in an individual patient in a dormant state only to grow as metastatic disease in the future, is in our view incontrovertibly established. Convincing too is the evidence that surgery to remove the primary tu
Autor:
J Norvell, M Valencik, Iain L. O. Buxton, H Tian, S H Barsky, Joseph Tellez, Nucharee Yokdang
Publikováno v:
British Journal of Cancer
Background: Human breast carcinoma cells secrete an adenosine 5′-diphosphate transphosphorylase (sNDPK) known to induce endothelial cell tubulogenesis in a P2Y receptor-dependent manner. We examined sNDPK secretion and its effects on human endothel
Publikováno v:
British Journal of Cancer
P2Y purine nucleotide receptors (P2YRs) promote endothelial cell tubulogenesis through breast cancer cell-secreted nucleoside diphosphate kinase (NDPK). We tested the hypothesis that activated P2Y(1) receptors transactivate vascular endothelial growt
Publikováno v:
Integrative Cancer Science and Therapeutics. 2
Nucleoside Diphosphate Kinase (NDPK), described as NM23 a metastasis suppressor, is found in the culture medium of cancer cells lines suggesting that the kinase may have an extracellular role. We propose that extracellular NM23 released from breast c
Publikováno v:
The FASEB Journal. 27
Autor:
Colleen A Sweeney, Mingyi Chen, Joseph Tellez, William J. Murphy, Jason Hatakeyama, Nucharee Yokdang, Jessica H. Wald, Manojit Mosur Swamynathan, Dennis Chang, Catalina Simion, Kermit L. Carraway
Publikováno v:
Cancer Research. 76:LB-021
LRIG1, a member of the LRIG family of transmembrane leucine rich repeat-containing proteins, is a negative regulator of receptor tyrosine kinase signaling and a tumor suppressor. LRIG1 expression is broadly decreased in human cancer and in breast can
Publikováno v:
Cancer letters. 291(2)
Several advances have recently expanded models of tumor growth and promoted the concept of tumor homeostasis, the hypothesis that primary tumors exert an anti-proliferative effect on both themselves and subclinical secondary metastases. Recent trials
Autor:
Colleen A Sweeney, Nucharee Yokdang
Publikováno v:
Cancer Research. 74:588-588
Leucine-rich repeats and immunoglobulin-like domains-1 (Lrig1) is known as a negative regulator of oncogenic receptor tyrosine kinases (ErbB, Met and Ret); and low Lrig1 expression correlates with poor patient prognosis in breast cancer. Lrig1 has be
Autor:
Nucharee Yokdang
Publikováno v:
Cancer Research. 70:LB-366
Cancer cells promote angiogenesis early in tumorigenesis under mutagenic/hypoxic conditions that drive oncogene expression of pro-angiogenic proteins. Clinical data suggest that by the time women are diagnosed with breast cancer, micrometastases are