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Akademický článek

Enhanced aortic stiffness in adolescents with chronic disease is associated with decreased left ventricular global longitudinal strain.

Autor: Verpalen VA; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands.; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, the Netherlands., Ververs FA; Center for Translational Immunology, University Medical Center Utrecht, the Netherlands., Slieker M; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., Nuboer R; Department of Pediatrics, Meander Medical Center Amersfoort, the Netherlands., Swart JF; Department of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., van der Ent CK; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., Fejzic Z; Department of Pediatric Cardiology, Amalia Children's Hospital Radboud University Medical Center Nijmegen, the Netherlands., Westenberg JJM; Department of Radiology, Leiden University Medical Center, the Netherlands., Leiner T; Department of Radiology, Mayo Clinics, United States of America., Grotenhuis HB; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands., Schipper HS; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, the Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, the Netherlands.; Department of Pediatric Cardiology, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, the Netherlands.

Publikováno v: International journal of cardiology. Heart & vasculature [Int J Cardiol Heart Vasc] 2024 Apr 26; Vol. 52, pp. 101385. Date of Electronic Publication: 2024 Apr 26 (Print Publication: 2024).

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Preclinical Aortic Atherosclerosis in Adolescents With Chronic Disease

Autor: Ververs, FA, Eikendal, ALM, Kofink, D, Nuboer, R, Westenberg, JJM, Hovenkamp, GT, Kemps, JJA, Coenen, ICJ, Daems, JJN, Claus, LR, Ju, Y, Wulffraat, NM, van der Ent, CK, Monaco, C, Boes, M, Leiner, T, Grotenhuis, HB, Schipper, HS

Publikováno v: Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease, 11(14). WILEY

Background Adolescents with chronic disease are often exposed to inflammatory, metabolic, and hemodynamic risk factors for early atherosclerosis. Since postmortem studies have shown that atherogenesis starts in the aorta, the CDACD (Cardiovascular Di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4de7e3a1ee1acaf751c04b9e4b842a
https://doi.org/10.1161/jaha.122.024675

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Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study

Autor: Bowman P., Sulen A., Barbetti F., Beltrand J., Svalastoga P., Codner E., Tessmann E. H., Juliusson P. B., Skrivarhaug T., Pearson E. R., Flanagan S. E., Babiker T., Thomas N. J., Shepherd M. H., Ellard S., Klimes I., Szopa M., Polak M., Iafusco D., Hattersley A. T., Njolstad P. R., Aisenberg J., Akkurt I., Abdul-Latif H., Al-Abdullah A., Barak L., Van Den Bergh J., Bertrand A. -M., Bizzarri C., Bonfanti R., Bruel H., Burrows A., Cadario F., Cameron F. J., Carson D., Cartigny M., Cauvin V., Cave H., Chakera A., Chetan R., Chiari G., Couch B., Coutant R., Cummings E., Dankovcikova A., Davis L., Deiss D., Delvecchio M., Faleschini E., Fauret A. -L., Finn R., Ford T., Franco E. D., Gallen B. D., Gasperikova D., Guntamukkala P., Hakeem V., Hasegawa S., Hathout E. H., Heffernan E., Hill D., Ho J., Hoarau M., Holl R., Hoddinott R., Houghton J., Howard N., Hughes N., Hunter I., Hogasen A. K., Kuulasmaa H., Ioacara S., Iotova V., Irgens H., Jaap A., Jones K., Kapellen T., Kaufman E., Klinge A., Klupa T., Krishnaswamy R., Lafferty T., LeGault L., Lambert P., Malecki M. T., Malievsky O., Mathew R., Mathews F., McVie R., Menzel U., Metz C., Meulen J. V. D., Modgil G., Mul D., Muther S., Nuboer R., O'Connell S. M., O'Riordan S., Palko M., Patel K. A., Pesavento R., Piccinno E., Pillai J. K., Pruhova S., Punthakee Z., Rabbone I., Raile K., Rincon M., Rose D., Sanchez J., Sandereson S., Saxena V., Schebek M., Schmidt D., Shehadeh N., Shiels J. P. H., Silva J. M. C. L., Stanik J., Tinklin T., Tjora E., Tumini S., Tuomi T., Uehara A., Velde R. V. D., Vermeulen G., Visser U., Voorhoeve P., Walker J., Weill J., Weisner T., Werner A., Williams T., Woodhead H., oddegard R.

Background: KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive potassium channel activation. 90% of patients successfully transfer from insulin to oral sulfonylureas with excellent initial glycaemic control; however,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f16e117352924005dbe878db63ef663a
http://hdl.handle.net/11591/398639

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Monocyte gene expression in childhood obesity is associated with obesity and complexity of atherosclerosis in adults

Autor: Keustermans, G C, Kofink, Daniel, Eikendal, A.L., de Jager, W., Meerding, J., Nuboer, R., Waltenberger, J., Kraaijeveld, A.O., Jukema, J Wouter, Sels, J.W., Garssen, J, Prakken, Berent J., Asselbergs, Folkert W, Kalkhoven, E., Hoefer, Imo E., Pasterkamp, G., Schipper, Henk S, Afd Pharmacology, Pharmacology

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, 7(1). Nature Publishing Group
Scientific Reports
Scientific Reports, 7(1). NLM (Medline)
Scientific reports, 7(ARTN 16826). Nature Publishing Group
Scientific Reports, 7
Scientific Reports, 7:16826. Nature Publishing Group

Childhood obesity coincides with increased numbers of circulating classical CD14++CD16- and intermediate CD14++CD16+ monocytes. Monocytes are key players in the development and exacerbation of atherosclerosis, which prompts the question as to whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28a08d6924a4c5ce00ec61645a13d6a
https://cris.maastrichtuniversity.nl/en/publications/7e0e68e3-6e52-4003-9801-2a314b407472

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Akademický článek

Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells.

Autor: Ververs FA; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Engelen SE; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Nuboer R; Department of Pediatrics, Meander Medical Center Amersfoort, Amersfoort, The Netherlands., Vastert B; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., van der Ent CK; Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Van't Land B; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Center of Excellence Immunology, Danone Nutricia Research, Utrecht, The Netherlands., Garssen J; Center of Excellence Immunology, Danone Nutricia Research, Utrecht, The Netherlands.; Division Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Beta Faculty, Utrecht University, Utrecht, The Netherlands., Monaco C; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Boes M; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Schipper HS; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands. h.s.schipper-3@umcutrecht.nl.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. h.s.schipper-3@umcutrecht.nl.; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. h.s.schipper-3@umcutrecht.nl.

Publikováno v: Scientific reports [Sci Rep] 2021 Oct 11; Vol. 11 (1), pp. 20082. Date of Electronic Publication: 2021 Oct 11.

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Akademický článek

Prevalence and course of mood and anxiety disorders, and correlates of symptom severity in adolescents with type 1 diabetes: Results from diabetes LEAP.

Autor: Nguyen LA; Department of Medical and Clinical Psychology, Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands.; Department of Medical Psychology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Pouwer F; Department of Psychology, University of Southern Denmark, Odense, Denmark.; School of Psychology, Deakin University, Geelong, Victoria, Australia.; STENO Diabetes Center Odense, Odense, Denmark., Winterdijk P; DIABETER, Diabetes Center, Rotterdam, The Netherlands., Hartman E; Department of Medical and Clinical Psychology, Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands., Nuboer R; Department of Pediatrics, Meander Medical Centre, Amersfoort, The Netherlands., Sas T; DIABETER, Diabetes Center, Rotterdam, The Netherlands.; Department of Pediatrics, Albert Schweitzer Hospital, Dordrecht, The Netherlands.; Department of Pediatric Endocrinology, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands., de Kruijff I; Department of Pediatrics, Diabetes Central, St. Antonius Hospital, Nieuwegein, The Netherlands., Bakker-Van Waarde W; DIABETER, Diabetes Center, Rotterdam, The Netherlands., Aanstoot HJ; DIABETER, Diabetes Center, Rotterdam, The Netherlands., Nefs G; Department of Medical and Clinical Psychology, Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands.; Department of Medical Psychology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.; DIABETER, Diabetes Center, Rotterdam, The Netherlands.

Publikováno v: Pediatric diabetes [Pediatr Diabetes] 2021 Jun; Vol. 22 (4), pp. 638-648. Date of Electronic Publication: 2021 Mar 16.

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