Differentiation of NK1.1+, Ly49+ NK cells from flt3+ multipotent marrow progenitor cells

Autor: Ns, Williams, Klem J, Igor Puzanov, Pv, Sivakumar, Bennett M, Kumar V

Publikováno v: Europe PubMed Central

To delineate factors involved in NK cell development, we established an in vitro system in which lineage marker (Lin)-, c-kit+, Sca2+ bone marrow cells differentiate into lytic NK1.1+ but Ly49- cells upon culture in IL-7, stem cell factor (SCF), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59d1c2ff1a511eafcbe4cfb20260d152
https://pubmed.ncbi.nlm.nih.gov/10453005

Ontogeny and differentiation of murine natural killer cells and their receptors

Autor: Pv, Sivakumar, Igor Puzanov, Ns, Williams, Bennett M, Kumar V

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4d845b22ef5d16e03c21ea093e129ded
https://pubmed.ncbi.nlm.nih.gov/9586356

Diet-induced thermogenesis in patients with gastrointestinal cancer cachexia

Autor: NS Williams, Pmt Weston, Rfgj King, AW Goode

Publikováno v: Clinical science (London, England : 1979). 77(2)

1. Indirect calorimetry has been used to measure resting energy expenditure (REE) and the thermogenic response to a test meal (diet-induced thermogenesis) in groups of weight-stable and weight-losing patients with gastrointestinal adenocarcinoma. Ave

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07aff557256bf85255174d16f3c6212
https://pubmed.ncbi.nlm.nih.gov/2766653

Analogs of the anti-malaria drug mefloquine have broad-spectrum antifungal activity and are efficacious in a model of disseminated Candida auris infection.

Autor: Guin S; Department of Chemistry, School of Science and Engineering, Saint Louis University, Saint Louis, Missouri, USA., Montoya MC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Wang X; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA., Zarnowski R; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Andes DR; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Meyers MJ; Department of Chemistry, School of Science and Engineering, Saint Louis University, Saint Louis, Missouri, USA., Williams NS; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2024 Nov 06; Vol. 68 (11), pp. e0130124. Date of Electronic Publication: 2024 Oct 04.

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency.

Autor: Tesla R; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Center for Translational Neurodegeneration Research, Dallas, TX, USA., Guhl C; Faculty of Chemistry and Earth Sciences, Institute of Organic Chemistry and Macromolecular Chemistry, Friedrich Schiller University Jena, 07743, Jena, Germany., Werthmann GC; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Center for Translational Neurodegeneration Research, Dallas, TX, USA., Dixon D; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Center for Translational Neurodegeneration Research, Dallas, TX, USA., Cenik B; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Center for Translational Neurodegeneration Research, Dallas, TX, USA., Addepalli Y; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Liang J; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Fass DM; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Departments of Neurology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Rosenthal Z; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA., Haggarty SJ; Chemical Neurobiology Laboratory, Center for Genomic Medicine, Departments of Neurology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Williams NS; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Posner BA; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ready JM; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Herz J; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Joachim.Herz@utsouthwestern.edu.; Center for Translational Neurodegeneration Research, Dallas, TX, USA. Joachim.Herz@utsouthwestern.edu.; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX, USA. Joachim.Herz@utsouthwestern.edu.; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Joachim.Herz@utsouthwestern.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jul 20; Vol. 15 (1), pp. 6125. Date of Electronic Publication: 2024 Jul 20.