Zobrazeno 1 - 10
of 1 158
pro vyhledávání: '"Nrf2 pathway"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 16, Pp 105-112 (2024)
Purpose: To explore the effects of kiwifruit peel polyphenols (KPP) on the antioxidant capacity of lipopolysaccharide (LPS)-stressed Caco-2 cells. Methods: The viability of Caco-2 cells in different treatment groups was determined by the cell countin
Externí odkaz:
https://doaj.org/article/fc5cfd2ef6444935a71f1276e7272989
Autor:
Takeshi Yasuda, Tomohisa Takagi, Kohei Asaeda, Hikaru Hashimoto, Mariko Kajiwara, Yuka Azuma, Hiroaki Kitae, Yasuko Hirai, Katsura Mizushima, Toshifumi Doi, Ken Inoue, Osamu Dohi, Naohisa Yoshida, Kazuhiko Uchiyama, Takeshi Ishikawa, Hideyuki Konishi, Yuichi Ukawa, Akiko Kohara, Masatake Kudoh, Ryo Inoue, Yuji Naito, Yoshito Itoh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Maintaining the mucus layer is crucial for the innate immune system. Urolithin A (Uro A) is a gut microbiota-derived metabolite; however, its effect on mucin production as a physical barrier remains unclear. This study aimed to elucidate the
Externí odkaz:
https://doaj.org/article/52427b2d7a264fa0b2fe3c9fb621bc4e
Autor:
Xiaobing Lan, Qing Wang, Yue Liu, Qing You, Wei Wei, Chunhao Zhu, Dongmei Hai, Zhenyu Cai, Jianqiang Yu, Jian Zhang, Ning Liu
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103406- (2024)
Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that occurs when blood supply is restored to ischemic brain tissue and is one of the leading causes of adult disability and mortality. Multiple pathological mechanisms are
Externí odkaz:
https://doaj.org/article/8a82f93d358f4334843dcfc85b474cf3
Autor:
Mohammadbagher Nasrabadi, Maryam Nazarian, Majid Darroudi, Somayeh Marouzi, Mohammad Sadra Harifi-Mood, Saeed Samarghandian, Tahereh Farkhondeh
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 148-157 (2024)
Carbamate (CBs) is a class of insecticides which is being known as an important cause of intentional or accidental poisoning. CBs, cause carbamylation of acetylcholinesterase at neuronal synapses and neuromuscular junction. Exposure to CBs through sk
Externí odkaz:
https://doaj.org/article/ae0cea2610f0404da95cb2a3de244843
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background Osteonecrosis of the femoral head caused by glucocorticoids (GIONFH) is a significant issue resulting from prolonged or excessive clinical glucocorticoid use. Astaxanthin, an orange-red carotenoid present in marine organisms, has
Externí odkaz:
https://doaj.org/article/59516528ac9a461cb9f734f060f2963e
Autor:
Xin Jin, Yunyun Mei, Puyu Yang, Runze Huang, Haifeng Zhang, Yibin Wu, Miao Wang, Xigan He, Ziting Jiang, Weiping Zhu, Lu Wang
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-10 (2024)
Abstract Background The integration of transcriptomic, proteomic, druggable genetic and metabolomic association studies facilitated a comprehensive investigation of molecular features and shared pathways for cancers’ development and progression. Me
Externí odkaz:
https://doaj.org/article/b18640fd503c493ab10ca2bbdfd8824c
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116863- (2024)
Cadmium (Cd) is a toxic heavy metal pollutant in the environment. Excessive Cd in water has toxic effects on fish, endangering their healthy growth and ultimately affecting the quality and safety of aquatic products. To evaluate the toxicity of exces
Externí odkaz:
https://doaj.org/article/9fa8d12e4b6b4a1d9df260e29c19e284
Publikováno v:
PeerJ, Vol 12, p e17933 (2024)
LncRNA is a type of transcript with a length exceeding 200 nucleotides, which was once considered junk transcript with no biological function during the transcription process. In recent years, lncRNA has been shown to act as an important regulatory f
Externí odkaz:
https://doaj.org/article/807539d167304e50a520ee747375d8dc
Autor:
Weixia Ji, Qiuyan Huang, Qiqi Ma, Xingxing Song, Xin Zhang, Xun Li, Xiaoye Wang, Sutian Wang, Yanling Wang, Zhengzhong Xiao, Chuanhuo Hu
Publikováno v:
Veterinary Sciences, Vol 11, Iss 11, p 543 (2024)
PTD-FNK, a synthetic anti-apoptotic protein, has been shown to potently alleviate cellular injuries. However, the effects of PTD-FNK on oxidative defense in boar testicular Sertoli cells (SCs) against oxidative injury has not been explored. In this s
Externí odkaz:
https://doaj.org/article/0ed1d7a734474fbea0ceb115a4c264c2
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1224 (2024)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which kidney involvement, so-called lupus nephritis (LN), is common and one of the most severe manifestations. Oxidative stress (OS) may play a role in the pathogenesis of LN throu
Externí odkaz:
https://doaj.org/article/c51f2596704e449dbe309c43f6238d6e